The primary use of Brimonidine + Brinzolamide is the management of open-angle glaucoma and ocular hypertension. It belongs to the group of medications known as alpha-2 adrenergic agonists and carbonic anhydrase inhibitors.
This combination medicine may also be used for other conditions as determined by a doctor.
Eye redness
Irritation or discomfort in the eye
Blurred vision
Headache
Brimonidine is an alpha-2 adrenergic agonist. It lowers the pressure in the eyes by reducing the amount of fluid produced (called aqueous humour) and increasing its flow out of the eyes.
Brinzolamide is a carbonic anhydrase inhibitor. It acts on special enzymes in the eye known as carbonic anhydrases, which are involved in the production of aqueous humour. Working together, Brimonidine and Brinzolamide effectively control eye pressure to manage conditions such as open-angle glaucoma and ocular hypertension.
Doctor of Medicine
BMS, FMC, MD Resident
Brimonidine + Brinzolamide is available as a sterile ophthalmic suspension, more commonly known as eye drops.
This medicine is generally approved for use in adults and children above the age of 2 years.
Brimonidine + Brinzolamide is contraindicated in individuals with known hypersensitivity to either of the active ingredients or any component of the formulation.
It is also contraindicated in patients with severe renal impairment, hyperchloremic acidosis, and acute angle-closure glaucoma.
Brimonidine + Brinzolamide may interact with other ocular medications such as miotics (like acetylcholine chloride, pilocarpine hydrochloride) , antihypertensives (like atenolol or amlodipine), antidepressants (such as phenelzine, amitriptyline), cardiac medications (such as digoxin or quinidine) and carbonic anhydrase inhibitors (like aspirin or acetazolamide).
In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
If you miss a dose, it should be administered as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do not double up on doses to compensate for a missed one.
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage dry eyes, consider using artificial tear drops (over-the-counter) to keep your eyes lubricated.
For managing a bitter taste in the mouth, rinse your mouth with water immediately after applying the eye drops.
Brimonidine + Brinzolamide may cause blurred vision or dizziness. If you experience these side effects, avoid driving or operating heavy machinery until your vision has cleared.
The safety of Brimonidine + Brinzolamide during pregnancy and lactation is not fully established. Consult your doctor before using this medication if you are pregnant or nursing.
Patients with liver or heart disease should use Brimonidine + Brinzolamide with caution as it may alter the body's ability to metabolise and excrete the medication.
This medicine should also be used with caution in individuals with blood vessel disorders.
Regular eye examinations are essential to monitor the progress of glaucoma or ocular hypertension.
Protect your eyes from dust and direct sunlight by wearing sunglasses when outdoors.
Follow a healthy diet rich in vitamins A and C, as they are essential for eye health.
Frequently asked questions
No, Brimonidine + Brinzolamide is not a steroid. It is a combination medicine that includes brimonidine, an alpha-2 adrenergic agonist, and brinzolamide, a carbonic anhydrase inhibitor.
Brimonidine + Brinzolamide is not associated with effects on sleep. This is used to lower intraocular pressure in conditions like glaucoma and has no known impact on sleep.
Brimonidine + Brinzolamide is not associated with effects on fertility. This is used to treat glaucoma and does not have a known impact on reproductive health.
Yes, it is safe to use this medication daily as prescribed by your doctor for the management of conditions like open-angle glaucoma and ocular hypertension.
The exact time for the onset of action of this combination may vary, but typically patients may see a decrease in intraocular pressure within two hours of administration.
Brimonidine + Brinzolamide should be instilled into the affected eye(s) daily as directed by your doctor.
No natural alternatives have been proven to have the same efficacy as Brimonidine + Brinzolamide in managing open-angle glaucoma and ocular hypertension. It is important to follow your doctor's advice about using this medicine for effective management of your condition.
Brimonidine + Brinzolamide in other salts
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