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Brimonidine + Brinzolamide

Uses of Brimonidine + Brinzolamide

  • The primary use of Brimonidine + Brinzolamide is the management of open-angle glaucoma and ocular hypertension. It belongs to the group of medications known as alpha-2 adrenergic agonists and carbonic anhydrase inhibitors.

  • This combination medicine may also be used for other conditions as determined by a doctor.

Side effects of Brimonidine + Brinzolamide

  • Eye redness

  • Irritation or discomfort in the eye

  • Blurred vision

  • Headache

How Brimonidine + Brinzolamide works

  • Brimonidine is an alpha-2 adrenergic agonist. It lowers the pressure in the eyes by reducing the amount of fluid produced (called aqueous humour) and increasing its flow out of the eyes.

  • Brinzolamide is a carbonic anhydrase inhibitor. It acts on special enzymes in the eye known as carbonic anhydrases, which are involved in the production of aqueous humour. Working together, Brimonidine and Brinzolamide effectively control eye pressure to manage conditions such as open-angle glaucoma and ocular hypertension.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Brimonidine + Brinzolamide is available as a sterile ophthalmic suspension, more commonly known as eye drops.

Age and Dose Restrictions

  • This medicine is generally approved for use in adults and children above the age of 2 years.

Contraindications

  • Brimonidine + Brinzolamide is contraindicated in individuals with known hypersensitivity to either of the active ingredients or any component of the formulation.

  • It is also contraindicated in patients with severe renal impairment, hyperchloremic acidosis, and acute angle-closure glaucoma.

Other Medications to Avoid

  • Brimonidine + Brinzolamide may interact with other ocular medications such as miotics (like acetylcholine chloride, pilocarpine hydrochloride) , antihypertensives (like atenolol or amlodipine), antidepressants (such as phenelzine, amitriptyline), cardiac medications (such as digoxin or quinidine) and carbonic anhydrase inhibitors (like aspirin or acetazolamide).

Overdose and Missed Dose

  • In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

  • If you miss a dose, it should be administered as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do not double up on doses to compensate for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage dry eyes, consider using artificial tear drops (over-the-counter) to keep your eyes lubricated.

  • For managing a bitter taste in the mouth, rinse your mouth with water immediately after applying the eye drops.

Use in Driving and Operating Machinery

  • Brimonidine + Brinzolamide may cause blurred vision or dizziness. If you experience these side effects, avoid driving or operating heavy machinery until your vision has cleared.

Use in Pregnancy and Lactation

  • The safety of Brimonidine + Brinzolamide during pregnancy and lactation is not fully established. Consult your doctor before using this medication if you are pregnant or nursing.

Caution in Other Conditions

  • Patients with liver or heart disease should use Brimonidine + Brinzolamide with caution as it may alter the body's ability to metabolise and excrete the medication.

  • This medicine should also be used with caution in individuals with blood vessel disorders.

Special Dietary and Lifestyle Recommendations

  • Regular eye examinations are essential to monitor the progress of glaucoma or ocular hypertension.

  • Protect your eyes from dust and direct sunlight by wearing sunglasses when outdoors.

  • Follow a healthy diet rich in vitamins A and C, as they are essential for eye health.

Frequently asked questions

No, Brimonidine + Brinzolamide is not a steroid. It is a combination medicine that includes brimonidine, an alpha-2 adrenergic agonist, and brinzolamide, a carbonic anhydrase inhibitor.

Brimonidine + Brinzolamide is not associated with effects on sleep. This is used to lower intraocular pressure in conditions like glaucoma and has no known impact on sleep.

Brimonidine + Brinzolamide is not associated with effects on fertility. This is used to treat glaucoma and does not have a known impact on reproductive health.

Yes, it is safe to use this medication daily as prescribed by your doctor for the management of conditions like open-angle glaucoma and ocular hypertension.

The exact time for the onset of action of this combination may vary, but typically patients may see a decrease in intraocular pressure within two hours of administration.

Brimonidine + Brinzolamide should be instilled into the affected eye(s) daily as directed by your doctor.

No natural alternatives have been proven to have the same efficacy as Brimonidine + Brinzolamide in managing open-angle glaucoma and ocular hypertension. It is important to follow your doctor's advice about using this medicine for effective management of your condition.

Terms & Conditions


Available medicines for BRIMONIDINE + BRINZOLAMIDE
Sentibrim Bz Ophthalmic Suspension 5ml
Sentibrim Bz Ophthalmic Suspension 5ml
Sentiss Pharma
Pack of 5 ML
₹344.40
MRP ₹420.00
18.00% OFF
B2doc Eye Drops 5ml
B2doc Eye Drops 5ml
Lupin Ltd
Pack of 5 ML
₹395.69
MRP ₹482.55
18.00% OFF
Synca Ls Eye Drops 5ml
Synca Ls Eye Drops 5ml
Sun Pharma Laboratories Ltd.
Pack of 5 ML
₹388.68
MRP ₹474.00
18.00% OFF
Brinzolast Eye Drops 5ml
Brinzolast Eye Drops 5ml
Mankind Pharmaceuticals Ltd.
Pack of 5 ML
₹360.80
MRP ₹440.00
18.00% OFF
Brinmide B Eye Drop 5 ML
Brinmide B Eye Drop 5 ML
Neomedix Healthcare India Pvt Ltd
Pack of 5 ML
₹385.40
MRP ₹470.00
18.00% OFF
Brinmide B Eye Drop 10 ML
Brinmide B Eye Drop 10 ML
Neomedix Healthcare India Pvt Ltd
Pack of 10 ML
₹656.00
MRP ₹800.00
18.00% OFF
Maxbrim Pf Bak Free Opthalmin Suspension 5ml
Maxbrim Pf Bak Free Opthalmin Suspension 5ml
Intas Pharmaceuticals Ltd
Pack of 5 ML
₹541.20
MRP ₹660.00
18.00% OFF

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