Brimonidine + Brinzolamide

Dosage Forms Available

• Brimonidine + Brinzolamide is available as a sterile ophthalmic suspension, more commonly known as eye drops.

Age and Dose Restrictions

• This medicine is generally approved for use in adults and children above the age of 2 years.

Contraindications

• Brimonidine + Brinzolamide is contraindicated in individuals with known hypersensitivity to either of the active ingredients or any component of the formulation.

• It is also contraindicated in patients with severe renal impairment, hyperchloremic acidosis, and acute angle-closure glaucoma.

Other Medications to Avoid

• Brimonidine + Brinzolamide may interact with other ocular medications such as miotics (like acetylcholine chloride, pilocarpine hydrochloride) , antihypertensives (like atenolol or amlodipine), antidepressants (such as phenelzine, amitriptyline), cardiac medications (such as digoxin or quinidine) and carbonic anhydrase inhibitors (like aspirin or acetazolamide).

Overdose and Missed Dose

• In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

• If you miss a dose, it should be administered as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose. Do not double up on doses to compensate for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage dry eyes, consider using artificial tear drops (over-the-counter) to keep your eyes lubricated.

• For managing a bitter taste in the mouth, rinse your mouth with water immediately after applying the eye drops.

Use in Driving and Operating Machinery

• Brimonidine + Brinzolamide may cause blurred vision or dizziness. If you experience these side effects, avoid driving or operating heavy machinery until your vision has cleared.

Use in Pregnancy and Lactation

• The safety of Brimonidine + Brinzolamide during pregnancy and lactation is not fully established. Consult your doctor before using this medication if you are pregnant or nursing.

Caution in Other Conditions

• Patients with liver or heart disease should use Brimonidine + Brinzolamide with caution as it may alter the body's ability to metabolise and excrete the medication.

• This medicine should also be used with caution in individuals with blood vessel disorders.

Special Dietary and Lifestyle Recommendations

• Regular eye examinations are essential to monitor the progress of glaucoma or ocular hypertension.

• Protect your eyes from dust and direct sunlight by wearing sunglasses when outdoors.

• Follow a healthy diet rich in vitamins A and C, as they are essential for eye health.