Home/Drugs By Ailments / Calamine + Diphenhydramine + Ethanol

Calamine + Diphenhydramine + Ethanol

Uses of Calamine + Diphenhydramine + Ethanol

  • Calamine + Diphenhydramine + Ethanol is predominantly used for the temporary relief of itching and discomfort associated with minor skin irritations and belongs to a class of medications known as topical antipruritics.

  • Secondary uses include management of symptoms such as skin redness and irritation due to conditions like poison ivy, poison oak, sunburn, insect bites and stings, prickly heat and minor cuts and scrapes.

Side effects of Calamine + Diphenhydramine + Ethanol

  • Temporary burning or stinging sensation at the application site

  • Skin dryness

  • Skin peeling or flaking

  • Mild skin rash

How Calamine + Diphenhydramine + Ethanol works

  • Calamine + Diphenhydramine + Ethanol is a therapeutic combination designed to manage skin irritations.

  • Calamine acts as a mild astringent that dries out tissues and forms a protective barrier on the skin, relieving itching and reducing the spread of irritation.

  • Diphenhydramine is an antihistamine. It competes with histamine for receptor sites within the body, blocking its effects, which reduces itching, redness, and swelling. It also has local anaesthetic properties to numb the affected area and provides a drying effect after penetrating the skin.

  • Ethanol acts as an antiseptic to help prevent infection while cooling and soothing the skin through evaporation. It also enhances the drying effect of calamine and diphenhydramine.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Calamine + Diphenhydramine + Ethanol is available in the form of a topical lotion for external use.

Age and Dose Restrictions

  • This topical medication is suitable for adults and for children aged 2 years and older. For use in children under 2 years, it is advised to consult a doctor.

Contraindications

  • Calamine + Diphenhydramine + Ethanol is contraindicated in individuals with a known hypersensitivity to any of the ingredients.

Other Medications to Avoid

  • Calamine + Diphenhydramine + Ethanol may interact with other topical antihistamines (such as promethazine), astringents (like zinc oxide), and alcohol-based antiseptics.

Overdose and Missed Dose

  • An overdose of Calamine + Diphenhydramine + Ethanol may cause skin dryness, peeling or flaking. If you observe these symptoms, consult a doctor immediately.

  • If you forget to apply this medicine, use it as soon as you remember. But avoid applying extra to make up for the missed dose.

Management of Side Effects

Most side effects of Calamine + Diphenhydramine + Ethanol are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

  • To manage skin dryness or peeling caused by the medicine, moisturise the skin regularly with a hypoallergenic cream or lotion.

  • Avoid scratching the treated area to help reduce irritation.

  • Applying a cold compress on the affected area may help alleviate burning or stinging sensations.

Use in Driving and Operating Machinery

  • Calamine + Diphenhydramine + Ethanol is a topical medication and does not affect your ability to drive or operate heavy machinery.

Use in Pregnancy and Lactation

  • If you are pregnant or breastfeeding, it is recommended to consult your doctor before using Calamine + Diphenhydramine + Ethanol.

Caution in Other Conditions

  • There are no specific medical conditions where caution needs to be taken when using Calamine + Diphenhydramine + Ethanol. However, it is advised not to use this medication on large areas of the body or for prolonged periods without consulting a doctor.

Special Dietary and Lifestyle Recommendations

  • Maintain good hygiene practices to help prevent skin irritation.

  • Wear loose, comfortable clothing made from natural fibres such as cotton to avoid further irritating the skin.

  • Limit exposure to sun and apply a broad-spectrum sunscreen when outdoors to protect the skin from sunburn.

  • Avoid contact with known allergens like poison ivy, poison oak, and poison sumac.

  • Use insect repellent when spending time outdoors to prevent insect bites.

  • Drink plenty of water to stay hydrated and keep your skin healthy.

Frequently asked questions

While Calamine + Diphenhydramine + Ethanol can help to relieve the symptoms of itching and skin irritation, it is advisable to consult your doctor before using this medication for managing eczema. Your doctor will be able to recommend the most appropriate treatment based on your specific condition and needs.

No, you should not apply Calamine + Diphenhydramine + Ethanol on open wounds, sores, or broken skin. It is meant to be used on intact skin only. If you have open wounds or broken skin, consult your doctor for suitable treatment options.

This medication can cause dryness of the skin as a side effect. Therefore, applying a moisturiser after using Calamine + Diphenhydramine + Ethanol may help prevent dryness and keep your skin hydrated. However, you should wait for the medication to dry completely before applying a moisturiser.

Yes, you can use sunscreen along with this medication. However, you should apply Calamine + Diphenhydramine + Ethanol first and let it dry completely before applying sunscreen.

Though rare, some people may be allergic to one or more ingredients in this medication which can cause allergic reactions like hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, seek immediate medical attention.

Yes, you can apply makeup after the application of this medication, but only after it has dried completely. However, keep in mind that the area of skin should be clean and dry before application of the medication.

Calamine, one of the ingredients, can leave a pink residue that may stain clothing. It is therefore advisable to let the medication dry completely before dressing.

Terms & Conditions


Available medicines for CALAMINE + DIPHENHYDRAMINE + ETHANOL
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