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Calcipotriol + Clobetasol Propionate

Uses of Calcipotriol + Clobetasol Propionate

  • Calcipotriol + Clobetasol Propionate is used to manage mild to moderate plaque psoriasis in adults and belongs to the group of corticosteroids and vitamin D analogues.

  • It offers an effective management strategy for psoriasis that has not responded adequately to other topical treatments.

Side effects of Calcipotriol + Clobetasol Propionate

  • Skin irritation

  • Itching

  • Redness

  • Burning at the application site

  • Potential for adrenal suppression and hypercalcaemia with excessive use

How Calcipotriol + Clobetasol Propionate works

  • Calcipotriol + Clobetasol Propionate is a combination medicine used for managing psoriasis.

  • Calcipotriol is a vitamin D analogue that helps in regulating the excessive growth of skin cells, which is a characteristic feature of psoriasis. It slows down the speed at which skin cells multiply, helping to reduce the formation of scaly plaques.

  • Clobetasol Propionate is a very potent corticosteroid. It works by suppressing the immune system responses in the skin that cause inflammation and itching, common symptoms of psoriasis.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Calcipotriol + Clobetasol Propionate is available as a topical medicine that is applied directly on the skin.

  • It comes in several formulations including ointment, cream, gel, and foam.

Age and Dose Restrictions

  • This combination medicine is intended for use by adults who are 18 years of age or older.

  • It is not recommended for children or adolescents below the age of 18.

Contraindications

  • Calcipotriol + Clobetasol Propionate is contraindicated in individuals with known hypersensitivity to any of its components.

  • It should not be applied on skin that has infections, such as viral (e.g., herpes or chickenpox), fungal, or bacterial infections.

  • The medicine is also contraindicated in individuals with skin manifestations of tuberculosis or syphilis, and on open skin wounds or abrasions.

Other Medications to Avoid

  • Calcipotriol + Clobetasol Propionate may interact with other topical corticosteroids (e.g., hydrocortisone), potentially increasing the risk of skin thinning or other local side effects. Additionally, using this combination with topical retinoids (e.g., tretinoin) can enhance irritation or dryness.

Overdose and Missed Dose

  • Overdose of Calcipotriol + Clobetasol Propionate may lead to symptoms such as adrenal suppression from systemic absorption of clobetasol and hypercalcemia from excessive use of calcipotriol. If you observe these symptoms, immediately inform your doctor.

  • If you forget to apply the medication at the scheduled time, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and follow your regular schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects of Calcipotriol + Clobetasol Propionate are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

  • If you experience skin irritation, you can try applying the medicine at a different time of day, preferably when you do not plan to be active which could cause more irritation.

  • If you experience redness or burning at the application site, try applying a smaller amount of the medicine and increase gradually as your body gets used to it.

Use in Driving and Operating Machinery

  • Calcipotriol + Clobetasol Propionate is a topical medicine and does not usually affect your ability to drive or operate machinery.

Use in Pregnancy and Lactation

  • Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or are breastfeeding.

Caution in Other Conditions

  • Calcipotriol + Clobetasol Propionate is applied topically on the skin and is not expected to have significant systemic absorption.

  • However, if you have a history of high calcium levels (hypercalcemia), inform your doctor as the calcipotriol component may affect calcium metabolism.

Special Dietary and Lifestyle Recommendations

  • If you are dealing with psoriasis, it is recommended to maintain a balanced diet rich in fruits, vegetables, lean proteins, and healthy fats.

  • Regular physical activity can help manage psoriasis symptoms by reducing stress and promoting better overall health.

  • Avoid triggers that can worsen the condition such as alcohol, smoking, stress, and excessive exposure to sunlight.

  • Keep your skin moisturized and avoid harsh soaps or cosmetics that can irritate the skin.

Frequently asked questions

Calcipotriol + Clobetasol Propionate is a combination medication that contains calcipotriol, a synthetic form of vitamin D, and clobetasol propionate, a highly potent corticosteroid. It is primarily used to manage psoriasis.

It is a topical medication and is not known to directly affect mood or hormones. However, if you notice any significant changes, it is important to consult with your doctor.

Calcipotriol + Clobetasol Propionate is a topical medication and does not contain any animal-derived ingredients, making it suitable for vegetarians and vegans. However, always check the ingredients list on the packaging and consult your doctor if you have any concerns.

Topical corticosteroids like clobetasol propionate can sometimes cause dependency if used for prolonged periods without medical supervision. However, this is rare and more likely with high-potency steroids used over large areas of the body. Always follow your doctor's advice on the duration and amount of application.

While some natural remedies may help alleviate the symptoms of psoriasis, they cannot replace prescribed treatments like Calcipotriol + Clobetasol Propionate. Always consult your doctor before trying new treatments or discontinuing prescribed medication.

There is no documented evidence suggesting that Calcipotriol + Clobetasol Propionate directly affects appetite or sleep. However, if you observe any unusual changes, contact your doctor.

Calcipotriol + Clobetasol Propionate is not available over the counter; you usually require a doctor's prescription to obtain this medication.

Terms & Conditions


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