Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc is primarily used for the management of internal and external haemorrhoids, and belongs to the group of vasoprotective and anti-inflammatory medications.
The combination can also be useful in relieving pain and discomfort associated with anal fissures, pruritus ani, and other inflammatory anorectal conditions.
Burning sensation at the application site
Mild itching or dryness
Redness or irritation of the skin
Rare cases of allergic reactions like rash or hives
Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc is a multi-therapeutic combination.
Calcium Dobesilate is a vasoprotective agent. It reduces capillary permeability, inhibits platelet aggregation, and enhances blood viscosity. This helps strengthen blood vessels, decrease leakage and swelling, and improve microcirculation in the affected area.
Hydrocortisone Acetate is a corticosteroid. It binds to glucocorticoid receptors and triggers anti-inflammatory responses. It reduces production of inflammatory mediators, inhibits immune cell activity, and constricts dilated blood vessels, thereby alleviating itching, inflammation, and swelling.
Lidocaine / Lignocaine is a local anaesthetic. It blocks voltage-gated sodium channels on nerve cell membranes, preventing the generation and conduction of nerve impulses. This results in a temporary loss of sensation and pain relief in the applied area.
Zinc acts as a mild astringent by precipitating proteins on the skin and mucosa. Topically, it helps soothe irritated tissues, reduce secretions and promote wound healing due to its antiseptic properties. Together, these four components work synergistically to manage symptoms associated with anorectal disorders such as haemorrhoids.
Doctor of Medicine
BMS, FMC, MD Resident
Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc is available in topical formulations as ointments or creams, and as suppositories or gels for rectal use.
The medication is applied directly to the affected area or used internally via rectal insertion depending on the specific formulation.
This medicine is meant for adults and is generally not recommended for use by children unless prescribed by a doctor.
This combination is contraindicated in patients with known hypersensitivity to any of the ingredients.
It is also contraindicated in patients with bacterial, viral, or fungal infections of the anorectal area, and those with tuberculosis or syphilis affecting the anal region.
This combination may interact with other corticosteroids (such as prednisone and dexamethasone), local anesthetics (including bupivacaine and ropivacaine), and medications affecting blood coagulation (like warfarin and heparin).
Overdose with Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc, applied topically, might intensify local side effects such as burning, stinging or redness. In case of accidental ingestion, symptoms like drowsiness or confusion can occur. Immediate medical attention is required in such scenarios.
If a dose is missed, it should be applied as soon as remembered unless it is almost time for the next application; in that case, skip the missed dose. Do not apply extra medication to make up for the missed dose.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If experiencing dryness or irritation at the application site, consider applying the medication at a different time of day.
Maintaining proper hydration may help alleviate minor irritation.
Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc does not generally affect the ability to drive or operate heavy machinery.
Consult a doctor before using Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc during pregnancy or while breastfeeding. The safety of its use in these conditions has not been firmly established.
Individuals with significant inflammation or immune suppression should use this medication cautiously.
Patients experiencing rectal bleeding of unknown cause should consult a doctor before using this medicine.
Increase fibre intake to help manage hemorrhoids; foods like fruits, vegetables, whole grains, and legumes can assist in softening the stool.
Stay hydrated by drinking plenty of water throughout the day; this helps prevent constipation, which can exacerbate hemorrhoidal discomfort.
Regular gentle exercise like walking can help reduce pressure on veins in the rectum and aid bowel function.
Avoid prolonged sitting or standing to decrease pressure on rectal veins.
Utilise proper techniques when lifting heavy objects to avoid straining that can worsen hemorrhoids.
Frequently asked questions
No, this medicine is specifically formulated for anorectal disorders such as hemorrhoids and anal fissures. Using it for other skin conditions may not be beneficial and could potentially cause harm. Always use medications as directed by your doctor.
This combination has several components that work together. Lidocaine numbs the area to relieve pain, hydrocortisone reduces inflammation and itching, calcium dobesilate strengthens vein walls and reduces swelling, and zinc aids in wound healing and infection prevention.
There are some people who should not use this medicine. It is contraindicated in patients with known hypersensitivity to any of its ingredients. It should also be used with caution in certain conditions, and it is recommended to consult a doctor before use.
Yes, mild burning or stinging on application is a common side effect of this medication and should subside after a few moments. If the sensation persists or worsens, discontinue use and consult your doctor.
The medication is typically applied as directed by your doctor.
Yes, Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine/Lignocaine + Zinc can be used during old age, but it’s important to use it under a doctor's supervision to monitor for potential side effects, especially due to the presence of hydrocortisone and lidocaine.
Though rare, allergic reactions such as rash or hives can occur. If you experience any symptoms of an allergic reaction, discontinue use and seek immediate medical attention.
Calcium Dobesilate + Hydrocortisone Acetate + Lidocaine / Lignocaine + Zinc in other salts
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