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Carvedilol + Ivabradine

Uses of Carvedilol + Ivabradine

  • Carvedilol + Ivabradine is primarily used to manage hypertension (high blood pressure). It belongs to the group of alpha and beta blockers and heart rate lowering medicines.

Side effects of Carvedilol + Ivabradine

  • Dizziness or lightheadedness

  • Fatigue

  • Headache

  • Slow heart rate (bradycardia)

  • Diarrhoea

How Carvedilol + Ivabradine works

  • Carvedilol is an alpha and beta blocker. It operates by obstructing the action of specific natural substances in the body, such as epinephrine, on the heart and blood vessels. This effect reduces the heart rate, blood pressure, and pressure on the heart.

  • Ivabradine, on the other hand, functions by reducing the heart rate, thereby lowering the oxygen demands of the heart. It achieves this by selectively inhibiting a special current, referred to as the "funny" current, within the sinus node - the natural pacemaker of the heart.

  • When used together, these two components enhance blood circulation and decrease the workload on the heart.

Certified content

Written By

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Ashmita BorgohainMedical Content Writer & Editor| 12 years

MSc (Applied Genetics)

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Carvedilol + Ivabradine is available as tablet for oral administration.

Age and Dose Restrictions

  • This medicine is intended for use in adults over 18 years of age.

Contraindications

Patients with the following conditions should not take Carvedilol + Ivabradine:

  • Severe liver failure

  • Symptoms of heart failure

  • Blood pressure less than 90/50 mmHg

  • Complete heart block (unless a functioning pacemaker is present)

  • Resting heart rate less than 60 beats per minute prior to treatment

  • Severe Chronic Obstructive Pulmonary Disease (COPD)

  • Cardiogenic shock where the heart is unable to pump enough blood to the rest of the body

  • Or a history of serious hypersensitivity reaction to either component of the medication.

Other Medications to Avoid

  • Carvedilol + Ivabradine may interact with other medications for high blood pressure or heart problems, with antibiotics (e.g., clarithromycin and telithromycin), antifungals (e.g., itraconazole and ketoconazole), antidepressants (e.g., nefazodone), anti-HIV medications (e.g., ritonavir), anti-seizure medications (e.g., phenobarbital and phenytoin), and herbal supplements (e.g., St. John's Wort).

  • Before starting any prescription or over-the-counter medicines, it is crucial to consult your doctor as certain combinations can lead to potentially harmful interactions.

Overdose and Missed Dose

  • Overdose of this medication may result in symptoms such as dizziness, slow heartbeat, breathing difficulties, and fainting. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of Carvedilol + Ivabradine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water may help manage some common side effects such as dry mouth and constipation.

  • If you experience dizziness upon standing, try getting up slowly from a sitting or lying position.

Use in Driving and Operating Machinery

  • Carvedilol + Ivabradine may cause side effects such as dizziness and fatigue which could affect your ability to drive or operate heavy machinery. Therefore, avoid these activities until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • Use of Carvedilol + Ivabradine during pregnancy or breastfeeding should be avoided unless recommended by your doctor. Consult your doctor before using this medicine if you are pregnant or nursing.

Caution in Other Conditions

  • Patients with known allergies to either component medication, asthma or other breathing problems, very low blood pressure (hypotension), severe liver problems, kidney problems, diabetes, thyroid disorders, or certain eye problems like retinitis pigmentosa should exercise caution while taking Carvedilol + Ivabradine.

Special Dietary and Lifestyle Recommendations

  • Maintain a low-sodium diet to better manage high blood pressure.

  • Limit alcohol intake as it can further lower blood pressure and may increase certain side effects of Carvedilol + Ivabradine.

  • Regular physical activity can help control high blood pressure.

  • Try to manage stress through techniques such as relaxation exercises and meditation.

Frequently asked questions

No, Carvedilol + Ivabradine is not a steroid. It is a combination of two active ingredients: Carvedilol, an alpha and beta blocker, and Ivabradine, a heart rate lowering medication.

Carvedilol + Ivabradine can cause dizziness or lightheadedness, which may affect some people's sleep. However, if you experience any sleeping problems while taking this medicine, it is important that you consult your doctor.

There is no specific information available on whether Carvedilol + Ivabradine affects fertility. If you have concerns about this issue, please consult your doctor.

There is no specific diet restriction while taking Carvedilol + Ivabradine. However, it should be taken with meals at approximately the same times each day.

Yes, it is usually safe to take Carvedilol + Ivabradine daily as prescribed by your doctor. However, it should not be used in certain patients such as those with severe liver impairment or blood pressure less than 90/50 mmHg.

The full blood pressure lowering effect of Carvedilol + Ivabradine may be seen within 1 to 2 weeks but it may take up to 4 weeks in some patients.

Carvedilol + Ivabradine should be taken with meals at approximately the same times each day as prescribed by your doctor.

Terms & Conditions


Carvedilol + Ivabradine in other salts

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