Cefixime + Ofloxacin

Dosage Forms Available

• Cefixime + Ofloxacin can be taken orally (tablet and suspension).

Age and Dose Restrictions

• This combination can be used in children and adults.

Contraindications

•  It is contraindicated in patients with a history of hypersensitivity to cefixime or/and ofloxacin.

Medications to Avoid with This Drug

• Avoid taking antacids, sucralfate, stomach acid reducers (cimetidine), immunosuppressants (cyclosporin), NSAIDs, antigout medications (probenecid), bronchodilators (theophylline), anticoagulants (warfarin), and antidiabetic agents (insulin, glyburide/glibenclamide). These medications may alter the safety and effectiveness of Cefixime + Ofloxacin.

Overdose and Missed Dose

• Overdose can cause confusion, dizziness, impairment of consciousness, convulsive seizures, and nausea, which need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
• If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management of Side Effects

• T​​ake this combination with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

• It is unlikely to impair the mental alertness or coordination required while driving.

Use in Pregnancy and Lactation

• Caution is advised during pregnancy and breastfeeding if this combination is prescribed.

Caution in Other Conditions

• Caution is advised in patients with hemolytic anaemia, severe diarrhoea, epilepsy, tendonitis and those with actual defects in glucose-6-phosphate dehydrogenase (G6PD) activity, myasthenia gravis, hypoglycemia, peripheral neuropathy, and kidney and liver impairment.

Special Dietary & Lifestyle Recommendation

• Finish the entire prescribed course, even if symptoms improve before completion, to ensure complete eradication of the infection.
• Limit or avoid alcohol consumption during the course of treatment, as they can potentially interact with the medications and affect their efficacy.
• Consider incorporating probiotics into your diet or as supplements to support gastrointestinal health, as antibiotics may affect the balance of gut bacteria.
• Ofloxacin may increase sensitivity to sunlight, so use sunscreen, wear protective clothing, and avoid excessive sun exposure.