Ceftriaxone + Tazobactam

Dosage Forms Available

• Ceftriaxone + Tazobactam is available as a powder that needs to be reconstituted before being used as an injection.
• This combination medicine is intended for intravenous administration.

Age and Dose Restrictions

• The use of Ceftriaxone + Tazobactam is suitable for both adults and children, subject to dosage adjustments.

Contraindications

• This medicine is contraindicated in patients with a known hypersensitivity to Ceftriaxone, Tazobactam, other cephalosporins, penicillins, or beta-lactamase inhibitors.
• It should also not be used in newborns with hyperbilirubinaemia, due to the risk of kernicterus.

Other Medications to Avoid with This Medicine

• This combination medicine may interact with aminoglycoside antibiotics, (such as amikacin, gentamicin, and tobramycin), anticoagulants, (such as warfarin and heparin), or oral contraceptives, (such as oestradiol and ethinyl oestradiol).

Overdose and Missed Dose

• In case of an overdose of this medicine, it may cause symptoms like severe stomach pain and shortness of breath. If you suspect an overdose, seek immediate medical assistance.
• If you miss a dose of this medicine, get it administered as soon as you can. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dose schedule.

Management of Side Effects

Most side effects are temporary, generally harmless, and resolve once you discontinue this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water may help to manage some of the gastrointestinal side effects like diarrhoea, nausea, and vomiting.
• Getting the medication administered after a meal may also help to reduce gastrointestinal discomfort.

Use in Driving and Operating Machinery

• Ceftriaxone + Tazobactam does not generally affect your ability to drive or operate heavy machinery. However, if you feel dizzy or unwell after administration of the injection, refrain from these activities until you feel better.

Use in Pregnancy and Lactation

• Ceftriaxone + Tazobactam can be used during pregnancy if needed, but only when recommended by your doctor.
• This medicine can pass into human milk in low concentrations. Therefore, it should be used with caution while breastfeeding.

Caution in Other Conditions

• Patients with kidney impairment should exercise caution when using this medicine, as dosage adjustments might be necessary.
• It should also be used carefully in patients with a history of seizures, gallbladder disease, pancreatitis, liver disease, or gastrointestinal diseases such as colitis.

Special Dietary and Lifestyle Recommendation

• Consuming a well-balanced diet rich in fruits and vegetables can boost the immune system and help fight infections.
• Regular hand washing and maintaining proper hygiene can help prevent bacterial infections.
• Smoking and alcohol can decrease the effectiveness of antibiotics; thus, it is advisable to limit their consumption during the treatment period.