Cefuroxime + Linezolid
Uses of Cefuroxime + Linezolid
Cefuroxime + Linezolid is mainly used to manage serious bacterial infections and falls under the category of combination antibiotic medications.
It is also used in the management of respiratory tract infections such as pneumonia, bronchitis, tonsillitis, skin and soft tissue infections like cellulitis, wound infections, abscesses, urinary tract infections (UTIs), and bone and joint infections like septic arthritis and osteomyelitis.
Side effects of Cefuroxime + Linezolid
Nausea
Vomiting
Diarrhoea
Abdominal pain
Rash
How Cefuroxime + Linezolid works
Cefuroxime, a second-generation cephalosporin antibiotic, works by inhibiting cell wall synthesis in bacteria. It specifically targets the enzymes known as penicillin-binding proteins (PBPs) that are vital for bacterial cell wall formation. As a result, the bacteria become structurally unstable, break open and die.
Linezolid, an oxazolidinone antibiotic, blocks the synthesis of proteins in bacteria. It specifically attaches to a part of the bacterial ribosomes, preventing them from making the essential proteins required for their growth and survival.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Cefuroxime + Linezolid can be taken orally (tablet).
Age and Dose Restrictions
Cefuroxime + Linezolid is suitable for use in adults and children above the age of 12 years.
Contraindications
Patients who have shown hypersensitivity or allergic reactions to either Cefuroxime or Linezolid should not use this combination medication. Individuals with a known allergy to other medicines in the cephalosporin or oxazolidinone classes should also avoid using this combination.
Other Medications to Avoid
Cefuroxime + Linezolid may interact with monoamine oxidase inhibitors (such as phenelzine, tranylcypromine), opioids (such as morphine, fentanyl), serotonergic antidepressants (such as fluoxetine, citalopram), and triptans (such as sumatriptan, rizatriptan).
Overdose and Missed Dose
Overdose of Cefuroxime + Linezolid can lead to symptoms such as convulsions, nausea, and vomiting. If an overdose is suspected, immediate medical attention should be sought.
If a dose of Cefuroxime + Linezolid is missed, it should be taken as soon as remembered. However, if it is near the time for the next dose, the missed dose should be skipped.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of fluids can help manage common side effects like nausea and diarrhoea.
Resting and refraining from strenuous activity can help manage dizziness or feeling faint.
Use in Driving and Operating Machinery
Cefuroxime + Linezolid may cause dizziness or confusion. Until you know how this medication affects you, avoid driving or operating heavy machinery.
Use in Pregnancy and Lactation
It is recommended to consult a doctor before using Cefuroxime + Linezolid during pregnancy and lactation.
Caution in Other Conditions
Patients with kidney disease or liver disease should exercise caution when taking Cefuroxime + Linezolid. Regular monitoring of kidney and liver function is advised.
Special Dietary and Lifestyle Recommendations
Regular physical activity can also contribute to general well-being and support the body's natural defence mechanisms.
Adequate rest is important during recovery from any infection.
Frequently asked questions
Does Cefuroxime + Linezolid affect the menstrual cycle?
No, Cefuroxime + Linezolid is not typically associated with affecting the menstrual cycle. However, every individual's body reactions can vary and if you notice any unusual changes in your menstrual cycle after starting this medication, you should consult your doctor immediately.
Is Cefuroxime + Linezolid a steroid medication?
No, Cefuroxime + Linezolid is not a steroid. It is a combination antibiotic medication that contains two active ingredients: Cefuroxime, a second-generation cephalosporin antibiotic, and Linezolid, an oxazolidinone antibiotic.
Can I take Cefuroxime + Linezolid for a viral infection?
No, Cefuroxime + Linezolid is an antibiotic and it is used to manage bacterial infections. Antibiotics do not work against viruses.
Does Cefuroxime + Linezolid cause mood changes?
While any medication can cause side effects that might include mood changes, Cefuroxime + Linezolid is not typically associated with mood changes.
Can Cefuroxime + Linezolid cause weight gain?
Weight gain has not been reported as a common side effect of Cefuroxime + Linezolid. If you notice any significant weight change while taking this medication, it would be best to consult your doctor.
Can I have dairy products while on Cefuroxime + Linezolid medication?
There are no specific dietary restrictions while taking Cefuroxime + Linezolid unless your doctor advises otherwise.
Are there vegetarian or vegan versions of Cefuroxime + Linezolid available?
The active ingredients of the medication are not derived from animal sources. However, you would need to check the individual product details or contact the manufacturer to confirm if the other ingredients in the tablet or capsule are suitable for vegetarians or vegans.
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