Home/Drugs By Ailments / Cetirizine + Phenylephrine

Cetirizine + Phenylephrine

Uses of Cetirizine + Phenylephrine

  • The primary use of Cetirizine + Phenylephrine is to provide relief from symptoms associated with allergic rhinitis, hay fever, and the common cold. This combination medicine belongs to the group of antihistamines and decongestants.

  • The medicine is also used to manage symptoms such as runny nose, sneezing, itchy eyes, watery eyes, nasal congestion, and sinus pressure.

Side effects of Cetirizine + Phenylephrine

  • Drowsiness

  • Dizziness

  • Dry mouth

  • Nausea

  • Trouble sleeping

How Cetirizine + Phenylephrine works

  • Cetirizine is used to relieve the symptoms of hay fever and other allergies.

  • Phenylephrine is used as to relieve nasal discomfort due to colds, hay fever.

  • Cetirizine + Phenylephrine is a combination that comprises an antihistamine and a decongestant.

  • Cetirizine is the antihistamine component. It targets and blocks H1 receptors, structures in our body that respond to histamine, a substance that triggers allergy symptoms. When Cetirizine blocks these receptors, it prevents histamine from creating allergic reactions, thereby relieving symptoms like runny nose, itching, and sneezing.

  • Phenylephrine is the decongestant part of the combination. It acts on alpha-adrenergic receptors, which are found in the walls of blood vessels in the nasal passages. Activation of these receptors by Phenylephrine causes the vessels to constrict or narrow down. These decreases swelling and inflammation in the nasal passages, providing relief from nasal congestion.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Cetirizine + Phenylephrine is available as an oral tablet.

  • It is to be taken by mouth, swallowed whole with a glass of water.

Age and Dose Restrictions

  • This medicine is meant for adults and children above 12 years of age.

  • Children below 12 years should not use this medication without a doctor's consultation.

Contraindications

  • This medicine is contraindicated in individuals who are hypersensitive to any of its components.

  • Patients with high blood pressure, heart disease, diabetes, thyroid disorders, glaucoma, or an enlarged prostate gland should also avoid using this combination.

Other Medications to Avoid

  • Cetirizine + Phenylephrine may interact with MAO inhibitors (like selegiline, linezolid), beta-blockers (such as atenolol, propranolol), alpha-blockers (like prazosin, terazosin), diuretics (like furosemide, hydrochlorothiazide), and antidepressants (like fluoxetine, sertraline).

Overdose and Missed Dose

  • An overdose of Cetirizine + Phenylephrine may cause extreme sleepiness, seizures, irregular heartbeat, and even coma. Immediate medical attention should be sought in case of an overdose.

  • If you miss a dose of this medication, take it as soon as you remember. However, avoid taking the missed dose if it is close to the time for your next dose. Do not double up on doses to compensate for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

  • For dry mouth, try chewing sugarless gum or sucking on sugarless hard candies. Frequent mouth rinses and adequate hydration can also help.

  • Try to rest and relax if you feel drowsy or dizzy.

Use in Driving and Operating Machinery

  • Cetirizine + Phenylephrine may cause drowsiness or dizziness, which could affect your ability to drive or operate heavy machinery. If you feel these effects after taking this medication, avoid such activities.

Use in Pregnancy and Lactation

  • It is advisable to consult your doctor before taking Cetirizine + Phenylephrine during pregnancy or while breastfeeding.

Caution in Other Conditions

  • Patients with conditions like high blood pressure, heart disease, and diabetes should exercise caution when using this medicine.

  • Those with thyroid disorders, glaucoma, or an enlarged prostate gland should also be cautious while using this combination.

Special Dietary and Lifestyle Recommendations

  • Regular hydration can alleviate some side effects like dry mouth associated with Cetirizine + Phenylephrine.

  • Avoid alcohol while taking this medication as it can increase the risk of side effects.

  • Maintain a balanced diet to support overall health while managing symptoms of allergic rhinitis, hay fever, and the common cold.

Frequently asked questions

No, there is no documented evidence that suggests that Cetirizine + Phenylephrine causes weight gain. However, if you notice any unusual changes in your body weight while taking this medication, please consult your doctor.

As with all medicines, Cetirizine + Phenylephrine should be used with caution in the elderly. Older individuals may be more sensitive to the side effects of this medicine, particularly drowsiness and dizziness. It is always best to consult your doctor before starting any new medication.

There is no evidence to suggest that taking Cetirizine + Phenylephrine will affect your mood or emotions. However, if you notice any changes in your mood or emotional state while taking this medicine, please consult your doctor.

Cetirizine + Phenylephrine is not known to interact with caffeine or foods containing caffeine. However, it is always best to consult your doctor if you have any concerns about interactions between your medication and food or drinks.

If you have a thyroid disorder, you should consult your doctor before taking Cetirizine + Phenylephrine. This medication should be used with caution in individuals with thyroid disorders.

The half-life of a medicine is the time it takes for the amount of the medicine in your body to reduce by half. The half-life of Cetirizine is approximately 8.3 hours, and for Phenylephrine it is about 2.5 hours. This means that it may take several days for this medication to be completely eliminated from your body.

While certain natural remedies may provide relief from symptoms of cold or allergies, they may not be as effective as Cetirizine + Phenylephrine. Always consult your doctor before starting any new treatment or medication.

Terms & Conditions


Cetirizine + Phenylephrine in other salts

CETIRIZINELEVOCETIRIZINELEVOCETIRIZINE + MONTELUKASTCETIRIZINE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PARACETAMOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + LEVOCETIRIZINELEVOCETIRIZINE + PSEUDOEPHEDRINECHLORPHENIRAMINE + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINECPM + DEXTROMETHORPHAN + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + MONTELUKASTCETIRIZINE + PSEUDOEPHEDRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBECLOMETHASONE DIPROPIONATE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINECALCIUM DOBESILATE + HYDROCORTISONE + LIDOCAINE / LIGNOCAINE + PHENYLEPHRINE + TROXERUTIN + ZINC OXIDEPHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECARBOXY METHYL CELLULOSE + NAPHAZOLINE + PHENYLEPHRINENAPHAZOLINE + PHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORBUTOL + PHENYLEPHRINE + TROPICAMIDECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE + DEXTROMETHORPHAN + MENTHOL + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESINBROMHEXINE + GUAIFENESIN + PHENYLEPHRINEBROMHEXINE + PHENYLEPHRINE + SALBUTAMOLAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + MENTHOLBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEPHENYLEPHRINE + TROPICAMIDECAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDECHLORPHENIRAMINE MALEATE + MENTHOL + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATECHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE + SODIUM CITRATELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE MALEATE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLPROPANOLAMINEAMBROXOL + LEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHENAMBROXOL + CETIRIZINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PSEUDOEPHEDRINECHLORPHENIRAMINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + GUAIFENESIN + PHENYLEPHRINEAMBROXOL + CETIRIZINE + DEXTROMETHORPHANDEXTROMETHORPHAN + PHENYLEPHRINE + TRIPROLIDINEAMBROXOL + CHLORPHENIRAMINE + GUAIFENESIN + MENTHOL + PHENYLEPHRINELEVOCETIRIZINE + PHENYLEPHRINECETIRIZINE + DEXTROMETHORPHANCETIRIZINE + DEXTROMETHORPHAN + PSEUDOEPHEDRINEAMBROXOL + GUAIFENESIN + LEVOCETIRIZINE + PHENYLEPHRINEBROMHEXINE + DEXTROMETHORPHAN + PHENYLEPHRINECHLORPHENIRAMINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DIETHYLCARBAMAZINECETIRIZINE + DEXTROMETHORPHAN HYDROBROMIDE + PHENYLEPHRINE HYDROCHLORIDECETIRIZINE + DEXTROMETHORPHAN + PHENYLEPHRINE HYDROCHLORIDECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + MENTHOL + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PHENYLEPHRINEACEBROPHYLLINE + LEVOCETIRIZINE + MONTELUKASTCAFFEINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + PSEUDOEPHEDRINECAFFEINE + DIPHENHYDRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECETIRIZINE + PARACETAMOL/ACETAMINOPHENCAFFEINE + CHLORPHENIRAMINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEFEXOFENADINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBROMHEXINE + CPM + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEBROMHEXINE + CHLORPHENIRAMINE MALEATE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINEAMBROXOL + LEVOCETIRIZINE + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CHLORPHENIRAMINE MALEATE + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINE HYDROCHLORIDELEVOCETIRIZINE + NIMESULIDE + PHENYLEPHRINEAMBROXOL + CETIRIZINE + GUAIFENESIN + PARACETAMOL/ACETAMINOPHEN + PHENYLEPHRINECAFFEINE + CETIRIZINE + NIMESULIDE + PHENYLEPHRINELEVOCETIRIZINE + PARACETAMOL/ACETAMINOPHEN
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