Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate

Dosage Forms Available

• Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate is available for ophthalmic use in the form of eye drops and eye ointment.

• The eye drops typically contain an aqueous base, suitable for instillation directly into the eyes. The ointment is based in sterile petrolatum, intended for application to the eyelids or directly to the eye surface.

Age and Dose Restrictions

• This combination is meant for use by adults and children.

Contraindications

• Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate is contraindicated in patients with known hypersensitivity to any of its components.

• It is also contraindicated in cases of untreated fungal, viral, or mycobacterial ocular infections and those with a history of angle-closure glaucoma or known steroid-induced intraocular pressure elevation.

Other Medications to Avoid

• Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate can interact with anticoagulants (such as warfarin), cancer medications (like imatinib), salicylates (like aspirin), antitubercular medications (like isoniazid), immunosuppressants (like cyclosporine), oral contraceptives (oestrogen-progesterone), and NSAIDs (like ibuprofen).

Overdose and Missed Dose

• In case you happen to put a few extra drops of this combination in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

• If you miss a dose of this medicine, apply it as soon as possible, unless it is almost time for your next dose. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage temporary burning or stinging that might occur immediately after application, close your eyes and rest briefly.

Use in Driving and Operating Machinery

• This combination may temporarily blur your vision or cause other visual disturbances, which could affect your ability to drive or operate machinery safely. Avoid these activities if you do not have clear vision after using this combination.

Use in Pregnancy and Lactation

• The safety of Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate during pregnancy and lactation has not been established. It is advised to consult your doctor before using this combination if you are pregnant or breastfeeding.

Caution in Other Conditions

• Patients with severe liver impairment need to exercise caution when using Chloramphenicol + Dexamethasone + Phenylmercuric Nitrate owing to potential toxicity.

Special Dietary and Lifestyle Recommendations

• Ensure adequate hydration to help maintain eye moisture.

• Practice good hygiene, especially around your eyes; wash hands thoroughly before applying eye medication.

• Wear sunglasses when outdoors to protect your eyes from UV rays which can aggravate eye conditions.