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Chloramphenicol + Dexamethasone + Polymyxin B

Uses of Chloramphenicol + Dexamethasone + Polymyxin B

  • Chloramphenicol + Dexamethasone + Polymyxin B is used primarily to manage bacterial eye infections, and it falls under the category of combined antibiotic and corticosteroid medicines.

  • It is also beneficial in the management of superficial infections of the eye and its adnexa such as conjunctivitis, keratitis, keratoconjunctivitis, blepharitis, and blepharoconjunctivitis.

Side effects of Chloramphenicol + Dexamethasone + Polymyxin B

  • Temporary burning or stinging upon instillation

  • Temporary blurred vision

  • Eye irritation or discomfort

  • Itching

  • Redness

How Chloramphenicol + Dexamethasone + Polymyxin B works

  • Chloramphenicol + Dexamethasone + Polymyxin B is a combination medicine for managing bacterial eye infections.

  • Chloramphenicol is a broad-spectrum antibiotic. It works by stopping bacterial protein synthesis, thereby inhibiting the growth and multiplication of bacteria.

  • Dexamethasone is a potent corticosteroid. It reduces inflammation by suppressing pro-inflammatory mediators and blocking white blood cells from reaching the infected area. This helps to reduce symptoms such as redness, swelling, and pain.

  • Polymyxin B is an antibiotic effective against many gram-negative bacteria. It destroys the bacterial cell membrane, causing leakage of cell contents and leading to bacterial cell death.

Certified content

Written By

docImg
Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Chloramphenicol + Dexamethasone + Polymyxin B is available for topical use as eye drops and eye ointment.

Age and Dose Restrictions

  • This medicine is intended for use in adults and children but requires a specific dosage adjustment based on age. Specific age recommendations may vary, so consult your doctor for guidance.

Contraindications

  • Chloramphenicol + Dexamethasone + Polymyxin B is contraindicated in patients with viral or fungal eye infections where corticosteroids could worsen the condition.

  • It is also contraindicated in patients with a known hypersensitivity to any of its components.

Other Medications to Avoid

  • Chloramphenicol + Dexamethasone + Polymyxin B can interact with other eye medications (such as timolol or atropine), which may alter their effects or increase adverse reactions.

Overdose and Missed Dose

  • In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

  • If you miss a dose of this medicine, administer it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Minor side effects like transient burning or stinging can be managed by ensuring correct administration techniques and avoiding touching the dropper tip to any surface to prevent contamination.

  • Temporary blurred vision might occur right after application; it is advisable not to perform activities that require clear vision immediately after application.

Use in Driving and Operating Machinery

  • The use of Chloramphenicol + Dexamethasone + Polymyxin B can cause temporary blurred vision or other visual disturbances which may affect your ability to drive or operate machinery. Avoid these activities until your vision is clear.

Use in Pregnancy and Lactation

  • It is recommended to consult your doctor before using Chloramphenicol + Dexamethasone + Polymyxin B if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients who have existing conditions such as glaucoma, or diabetes mellitus, or those who have recently had eye surgery should be cautious when using Chloramphenicol + Dexamethasone + Polymyxin B due to potential increased risks of adverse effects or complications.

Special Dietary and Lifestyle Recommendations

  • Ensure proper hygiene by washing hands thoroughly before applying eye drops or ointment to avoid contaminating the dropper and infecting the eyes.

  • Patients using Chloramphenicol + Dexamethasone + Polymyxin B should avoid wearing contact lenses during treatment to prevent irritation and risk of infection.

  • Keeping a clean environment, and avoiding dusty or smoky areas can also help manage symptoms better while using this medication for eye conditions.

Frequently asked questions

Yes, one of the components in Chloramphenicol + Dexamethasone + Polymyxin B, namely Dexamethasone, is a corticosteroid. It helps to reduce inflammation in the eye.

There is no direct evidence or report suggesting that Chloramphenicol + Dexamethasone + Polymyxin B can affect sleep.

The research does not suggest that Chloramphenicol + Dexamethasone + Polymyxin B directly affects fertility. However, always consult with your doctor before taking any medication.

There are no specific diet restrictions while taking Chloramphenicol + Dexamethasone + Polymyxin B unless instructed by your doctor.

It is safe to use Chloramphenicol + Dexamethasone + Polymyxin B as prescribed by your doctor. Do not exceed the recommended dose and duration of use.

Symptoms typically improve within a few days of starting treatment with Chloramphenicol + Dexamethasone + Polymyxin B, however, treatment time will vary depending on individual conditions.

Chloramphenicol + Dexamethasone + Polymyxin B can be used at any time as directed by your doctor.

Terms & Conditions


Available medicines for CHLORAMPHENICOL + DEXAMETHASONE + POLYMYXIN B
Ocupol Dx Eye Ointment 5gm
Ocupol Dx Eye Ointment 5gm
Centaur Pharmaceuticals Pvt.ltd
Pack of 5 GM
₹108.31
MRP ₹132.08
18.00% OFF
Deximon Px Eye/ear Drops 5 ML
Deximon Px Eye/ear Drops 5 ML
Entod Pharmaceuticals Ltd
Pack of 5 ML
₹71.75
MRP ₹87.50
18.00% OFF
Ocupol D Eye/ear Drops 5 ML
Ocupol D Eye/ear Drops 5 ML
Centaur Pharmaceuticals Pvt.ltd
Pack of 5 ML
₹11.02
MRP ₹13.44
18.00% OFF
Imix D Eye Ointment 5 GM
Imix D Eye Ointment 5 GM
Medivision Pharm
Pack of 5 GM
₹54.33
MRP ₹66.25
18.00% OFF
Biosone P Eye/ear Drops 5ml
Biosone P Eye/ear Drops 5ml
Nri Vision Care
Pack of 5 ML
₹57.40
MRP ₹70.00
18.00% OFF
Anchlor Dx Eye Ointment 5gm
Anchlor Dx Eye Ointment 5gm
Nri Vision Care
Pack of 5 GM
₹61.50
MRP ₹75.00
18.00% OFF
Dexoren Sp Eye Ointment 5gm
Dexoren Sp Eye Ointment 5gm
Indoco Remedies Ltd
Pack of 5 GM
₹93.48
MRP ₹114.00
18.00% OFF
Polynase D Eye Ointment 5gm
Polynase D Eye Ointment 5gm
Ajanta Pharma Ltd
Pack of 5 GM
₹109.88
MRP ₹134.00
18.00% OFF

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