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Chlordiazepoxide + Trifluoperazine

Uses of Chlordiazepoxide + Trifluoperazine

  • Chlordiazepoxide + Trifluoperazine is used to manage schizophrenia, a condition where people may experience hallucinations, delusions, or confusion. 
  • It combines a benzodiazepine and an antipsychotic to treat these symptoms. This medication can also be used to help with acute alcohol withdrawal and certain anxiety disorders.

Side effects of Chlordiazepoxide + Trifluoperazine

  • Drowsiness

  • Dry mouth

  • Dizziness

  • Constipation

  • Blurred vision

How Chlordiazepoxide + Trifluoperazine works

  • Chlordiazepoxide works by enhancing the activity of a neurotransmitter called GABA in the brain. GABA inhibits excessive neuronal activity, thus the action of Chlordiazepoxide leads to calming effects, reducing anxiety and managing convulsions.

  • Trifluoperazine, on the other hand, acts by blocking the action of dopamine, a chemical that transmits signals in the brain. By antagonising this dopamine activity, especially at D2 receptors, it reduces psychotic symptoms like hallucinations and delusions.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Chlordiazepoxide + Trifluoperazine can be taken orally (tablets).

Age and Dose Restrictions

  • This combination medicine is primarily meant for use in adults aged 18 and above.

Contraindications

  • Chlordiazepoxide + Trifluoperazine is contraindicated in patients with a known hypersensitivity to either chlordiazepoxide or trifluoperazine. It is also contraindicated in individuals with severe liver or kidney impairment, narrow-angle glaucoma, and bone marrow depression.

Other Medications to Avoid

  • Chlordiazepoxide + Trifluoperazine can interact with anticholinergic medicines (such as atropine and scopolamine) and oral anticoagulants (such as warfarin).

Overdose and Missed Dose

  • Overdose of Chlordiazepoxide + Trifluoperazine may lead to sedation, confusion, and slowed reflexes. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of this medication, take it as soon as you remember. If it is close to the time for your next dose, skip the missed one and go back to your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If you experience dry mouth after taking this medicine, try chewing sugar-free gum or sucking on sugar-free hard candies.

  • In case of constipation, incorporate dietary fibre into your meals and ensure adequate hydration.

Use in Driving and Operating Machinery

  • Chlordiazepoxide + Trifluoperazine may cause drowsiness and impaired coordination. You should avoid driving or operating machinery if you experience these effects.

Use in Pregnancy and Lactation

  • This combination medicine is not recommended for use during pregnancy and lactation unless deemed necessary by a doctor.

Caution in Other Conditions

  • Caution should be exercised when using Chlordiazepoxide + Trifluoperazine in patients with cardiovascular disease due to the potential for orthostatic hypotension.

  • It should also be used with caution in elderly patients due to an increased risk of sedation and falls.

Special Dietary and Lifestyle Recommendations

  • Avoiding caffeine and alcohol can help reduce anxiety and promote better sleep.

  • Stress management techniques such as yoga, meditation, or deep breathing exercises may be beneficial.

Frequently asked questions

No, Chlordiazepoxide + Trifluoperazine is not an antibiotic. It is a combination medicine used primarily for managing schizophrenia and related psychotic disorders.

Weight gain can potentially occur. If you notice any significant change in body weight while taking this medicine, please consult your doctor.

Chlordiazepoxide + Trifluoperazine should be used with caution in patients with cardiovascular disease. Always consult your doctor before starting any new medicine.

No, sudden discontinuation of Chlordiazepoxide + Trifluoperazine may lead to withdrawal symptoms. It is recommended that you gradually reduce the dose under the supervision of a doctor.

Chlordiazepoxide, one component of this combination, has the potential for dependence and withdrawal symptoms on abrupt discontinuation. It should be used only as prescribed by your doctor.

Chlordiazepoxide + Trifluoperazine is not classified as a mood stabiliser. It belongs to the group of benzodiazepines and antipsychotics and is primarily used for the management of schizophrenia and related psychotic disorders.

Yes, Chlordiazepoxide + Trifluoperazine may impair mental alertness and physical coordination. Therefore, patients should avoid activities such as driving or operating machinery while taking this medicine.

Terms & Conditions


Available medicines for CHLORDIAZEPOXIDE + TRIFLUOPERAZINE
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Cloxide Plus 1/10 MG Tablet 10
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Equizine 1/10 MG Tablet 10
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