Chlorthalidone + Metoprolol Succinate

Dosage Forms Available

• Chlorthalidone + Metoprolol Succinate is available for oral administration in the form of extended-release tablets.

Age and Dose Restrictions

• This combination medicine is generally prescribed for adult patients. The suitability for children below 18 years should be evaluated by a doctor.

Contraindications

• Chlorthalidone + Metoprolol Succinate is contraindicated in patients with known hypersensitivity to either of its active ingredients.

• It is also contraindicated in patients with cardiogenic shock, severe bradycardia, heart block greater than first-degree, untreated pheochromocytoma, and severe peripheral arterial circulatory disorders.

Other Medications to Avoid

• Chlorthalidone + Metoprolol Succinate may interact with other blood pressure medications (like furosemide and amlodipine), heart rhythm medications (like digoxin, digitoxin), insulin or oral diabetes medications (such as metformin and glipizide), NSAIDs (like ibuprofen or naproxen), antidepressants (like fluoxetine or paroxetine).

Overdose and Missed Dose

• Overdose of this combination may lead to severe hypotension, bradycardia, cardiac insufficiency, and cardiac arrest. In case of an accidental overdose, seek immediate medical attention.

• If you miss a dose of Chlorthalidone + Metoprolol Succinate, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For common side effects like dizziness or lightheadedness, it might be helpful to get up slowly when rising from a seated or lying position.

• Drinking plenty of water can help manage side effects such as constipation and dry mouth.

Use in Driving and Operating Machinery

• Chlorthalidone + Metoprolol Succinate may cause dizziness or tiredness. Therefore, caution is advised when driving or operating machinery.

Use in Pregnancy and Lactation

• It is advised to consult your doctor before using Chlorthalidone + Metoprolol Succinate during pregnancy or while breastfeeding because the potential risks and benefits must be weighed carefully.

Caution in Other Conditions

• Caution should be exercised when using this combination in patients with liver or kidney disease, diabetes, thyroid disorders, breathing problems (such as asthma, chronic bronchitis, emphysema), lupus, gout, circulation problems (such as Raynaud's disease or peripheral vascular disease), or heart problems (slow heartbeat, heart block, heart failure).

Special Dietary and Lifestyle Recommendations

• Maintain a low-salt diet to help control your blood pressure.

• Try to incorporate exercises into your daily routine to help manage high blood pressure.