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Choline + Cyproheptadine

Uses of Choline + Cyproheptadine

  • The primary use of Choline + Cyproheptadine is to stimulate appetite in individuals experiencing poor appetite or eating disorders such as anorexia nervosa. It belongs to a group of medications known as appetite stimulants and bile acid sequestrants.

  • In addition, this medicine is also prescribed for underweight children who are not eating adequately due to inadequate dietary intake, anaemia, liver disease or digestive disorders. It is sometimes used alongside other treatments like anti-tubercular and anti-HIV medications to boost appetite and promote weight gain.

Side effects of Choline + Cyproheptadine

  • Drowsiness

  • Dizziness

  • Dry mouth

  • Nausea

  • Blurred vision

How Choline + Cyproheptadine works

  • Choline is categorised as a bile acid binding agent. It operates by attaching itself to bile acids in your intestine and facilitating their expulsion from your body. This prompts the liver to utilise more cholesterol to produce new bile acids, which helps in enhancing your metabolic processes.

  • Cyproheptadine, on the other hand, is an antihistamine with appetite-stimulating attributes. It performs its function by obstructing the action of a chemical messenger known as serotonin. This occurs in a part of the brain referred to as the hypothalamus which controls appetite levels. By reducing the effects of serotonin, hunger pangs are increased.

Certified content

Written By

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Ashmita BorgohainMedical Content Writer & Editor| 12 years

MSc (Applied Genetics)

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Choline + Cyproheptadine can be taken orally (syrup, drops and tablets).

Age and Dose Restrictions

  • This combination medicine is for adults and children but is not recommended for newborns or premature infants.

Contraindications

  • Choline + Cyproheptadine is contraindicated for patients who have a known allergy to either of its active ingredients.

Other Medications to Avoid

  • Choline + Cyproheptadine may interact with sleeping pills (e.g., lorazepam, clonazepam), narcotics (e.g., codeine, oxycodone), antihistamines (e.g., diphenhydramine, cetirizine) and certain antidepressants and psychiatric medicines (e.g., fluoxetine and sertraline).

Overdose and Missed Dose

  • An overdose of Choline + Cyproheptadine may increase the side effects of drowsiness, dry mouth etc. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage dry mouth, sip water often and chew sugar-free gum to help stimulate saliva flow.

Use in Driving and Operating Machinery

  • This medicine may cause dizziness and drowsiness. It is advised to avoid driving or operating heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • Pregnant and breastfeeding women should consult their doctor before using this medicine.

Caution in Other Conditions

  • Patients with glaucoma, prostate enlargement, seizures, or overactive thyroid should exercise caution when taking this medicine.

  • Special care should also be taken by elderly patients who are more prone to side effects like drowsiness, dizziness and confusion.

Special Dietary and Lifestyle Recommendations

  • It is recommended to include foods rich in choline, such as meat, eggs, fish, dairy products and also potatoes, cruciferous vegetables such as brussels sprouts, broccoli, and cauliflower. It is a good option to consume some types of beans, nuts, seeds, and whole grains.

Frequently asked questions

Yes, one of the purposes of Choline + Cyproheptadine is to stimulate appetite, which may lead to weight gain.

Some foods and supplements may boost appetite or nutrition, but results can differ from those of this combination medicine. Always consult your doctor before trying alternatives or discontinuing prescribed medication.

Choline and Cyproheptadine mainly affect appetite and have minimal impact on mood. Individual responses vary, so consult your doctor if you experience unusual emotional changes.

Choline + Cyproheptadine does not contain animal-derived ingredients, but it may include gelatin or lactose. If you're strict about your vegetarian or vegan diet, consult your doctor about the medication’s contents.

Take Choline + Cyproheptadine only as directed by your doctor for the approved duration of treatment.

Choline + Cyproheptadine has no major food interactions, but follow your doctor's advice and inform them about your dietary habits and any dietary supplements you take.

Metabolism of choline and cyproheptadine varies by individual factors like age and liver function. They are generally processed by the liver and excreted by the kidneys quickly. Consult your doctor for specific details.

Terms & Conditions


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