Ciclopirox
Uses of Ciclopirox
Ciclopirox is primarily used to manage different types of fungal infections present on the skin, hair, and nails. It belongs to the class of antifungal medications.
Apart from its main usage, it is also used for managing conditions like athlete's foot (Tinea pedis), jock itch (Tinea cruris), ringworm of the body (Tinea corporis), cutaneous candidiasis, pityriasis (tinea) versicolor, seborrheic dermatitis of the scalp, and onychomycosis (fungal infection of fingernails and toenails). It can also be used as a part of comprehensive treatment for onychomycosis, which may include the removal of an infected nail.
Side effects of Ciclopirox
Application site reactions (burning, itching, redness, irritation)
Skin rash or irritation
Nail discolouration, shape changes, or irritation
Hair discolouration (with Ciclopirox shampoo)
How Ciclopirox works
Ciclopirox is a synthetic antifungal agent from the hydroxypyridone class.
It functions by chelating, that is, grabbing onto and bonding with trivalent metal ions (like iron Fe3+ and aluminium Al3+). These metal ions are key for certain enzymes in fungal cells, which help break down toxic peroxides. With Ciclopirox in action, these enzymes are inhibited, causing an accumulation of toxic peroxides within the fungal cells. This leads to the death of these fungal cells. Additionally, Ciclopirox appears to interfere with the fungal cell's ability to transport substances across its membrane and maintain its membrane integrity. This adds to its antifungal effectiveness.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Ciclopirox can be applied topically (cream, gel, or solution), scalp shampoo and nail lacquer.
Age and Dose Restrictions
This medicine is meant for adults and children above 10 years of age.
Contraindications
This medicine is contraindicated in individuals with a known hypersensitivity to Ciclopirox or to any of the ingredients in the formulation.
Other Medications to Avoid
Ciclopirox can interact with other antifungal agents (such as fluconazole and ketoconazole) and steroidal creams (such as hydrocortisone and betamethasone).
Overdose and Missed Dose
An overdose of topical Ciclopirox may cause excessive skin irritation. If this occurs, stop using the medication and inform your doctor immediately.
If you forget to apply Ciclopirox, do it as soon as you remember. However, if it is nearly time for your next application, skip the missed dose. Do not apply extra medicine to make up for a missed dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For minor skin irritation or redness at the site of application, consider applying a hypoallergenic moisturiser after applying Ciclopirox.
Drink plenty of water to stay hydrated if you experience dryness in the area where the medicine was applied.
Use in Driving and Operating Machinery
As Ciclopirox is a topical medication, it does not affect your ability to drive or operate heavy machinery.
Use in Pregnancy and Lactation
Consult your doctor before using this medicine if you are pregnant or breastfeeding.
Caution in Other Conditions
Patients with a history of severe skin conditions or allergies should exercise caution when using Ciclopirox.
Special Dietary and Lifestyle Recommendations
Maintain good body hygiene to prevent and control fungal infections. Regular cleaning and drying of the affected area can be beneficial.
Wearing breathable clothing and footwear can reduce the chance of developing fungal infections, especially those affecting the feet.
Avoid sharing personal items like towels, combs, or shoes that can spread fungal spores.
Frequently asked questions
Is Ciclopirox a steroid?
No, Ciclopirox is not a steroid. It is an antifungal medicine used to manage various types of fungal infections in the body.
Will Ciclopirox affect fertility?
Ciclopirox is not directly associated with affecting fertility. However, if you are planning to conceive or are pregnant, you should consult your doctor before using this medicine.
Is it safe to take Ciclopirox daily?
The safety of daily use of Ciclopirox depends on the specific condition being managed and the duration of therapy as prescribed by your doctor.
How much time does Ciclopirox take to work?
Ciclopirox usually starts working soon after application, but the time to see visible improvement depends on the severity and type of fungal infection.
What is the best time to take Ciclopirox?
Ciclopirox can be applied at any time as per the instructions provided by your doctor. However, for nail infections, it is often recommended to apply Ciclopirox at bedtime.
Does Ciclopirox affect the mood?
Ciclopirox is not directly associated with affecting mood. Consult your doctor before taking this medicine.
Are there any natural alternatives to Ciclopirox?
There may be natural remedies that can help manage some fungal infections, but it is always best to consult your doctor for advice specific to your condition before trying any alternatives.
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