Cinitapride + Pantoprazole
Uses of Cinitapride + Pantoprazole
Cinitapride + Pantoprazole is primarily used for managing gastroesophageal reflux disease (GERD) and peptic ulcer disease. It belongs to the group of gastroprokinetic and proton pump inhibitor (PPI) medicines.
Additionally, it is prescribed for healing of erosive esophagitis, maintaining healed erosive esophagitis, treating symptomatic GERD, short-term treatment of active benign gastric ulcers and active duodenal ulcers, eradication of Helicobacter pylori to reduce the risk of duodenal ulcer recurrence in combination with antibiotics, and long-term treatment of pathological hypersecretory conditions such as Zollinger-Ellison syndrome.
Side effects of Cinitapride + Pantoprazole
Headache
Diarrhoea
Nausea
Abdominal pain
Flatulence
How Cinitapride + Pantoprazole works
Cinitapride + Pantoprazole is a gastroprokinetic and proton pump inhibitor combination.
Cinitapride works by activating certain types of serotonin receptors (5-HT1 and 5-HT4) found on stomach and intestine muscles and nerves. This causes the release of a chemical called acetylcholine, which improves the movement of food through the stomach and intestines.
Pantoprazole acts by blocking an enzyme system (H+/K+ ATPase, also known as the proton pump) present on certain cells in the stomach. This stops the final step of acid production, reducing both the amount of acid made by the stomach under normal conditions and when stimulated (for example, by food). The combined action of these two components helps to relieve symptoms of gastroesophageal reflux disease and peptic ulcer disease by both speeding up digestion and reducing acid production in the stomach.
Certified content
Written By
MD Ayurveda
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Cinitapride + Pantoprazole can be taken orally (tablets and capsules).
Age and Dose Restrictions
This medication is suitable for adults and adolescents above the age of 18 years.
Contraindications
Cinitapride + Pantoprazole should not be used in patients who are known to be allergic to either of the components of the combination. It is also contraindicated in patients with severe liver disease.
Other Medications to Avoid
This combination may interact with antiviral medications (such as atazanavir, nelfinavir, and rilpivirine), blood thinning medications (like warfarin) and chemotherapy medicne (like methotrexate).
Overdose and Missed Dose
Overdosing on Cinitapride + Pantoprazole can lead to serious side effects. If you suspect an overdose, seek immediate medical attention.
If you miss a dose of Cinitapride + Pantoprazole, take it as soon as you remember. If it is time for your next dose, skip the missed dose and resume your regular schedule. Do not double your dose to make up for a missed one.
Management of Side Effects
Most side effects of Cinitapride + Pantoprazole are temporary and will resolve once you stop taking the medication. If you experience severe side effects or your symptoms worsen, consult your doctor immediately.
Drinking plenty of fluids can help manage side effects like dry mouth and constipation.
Stick to smaller, more frequent meals to manage gastrointestinal symptoms like nausea or upset stomach.
Use in Driving and Operating Machinery
Cinitapride + Pantoprazole may cause dizziness, sleepiness or blurred vision. If you experience these side effects, avoid driving or operating heavy machinery until you feel better.
Use in Pregnancy and Lactation
Cinitapride + Pantoprazole is not recommended for use during pregnancy and breastfeeding unless prescribed by your doctor. Consult your doctor for advice on whether you should continue to take this medication if you are pregnant or breastfeeding.
Caution in Other Conditions
Patients with liver problems should exercise caution when taking Cinitapride + Pantoprazole. Regular monitoring of liver function is advised in these patients.
Special Dietary and Lifestyle Recommendations
Avoid foods that can trigger heartburn, such as fried, fatty or spicy foods.
Avoid lying down or going to bed immediately after eating. It is recommended to wait at least three hours after eating before lying down or going to bed.
Frequently asked questions
Is Cinitapride + Pantoprazole a steroid?
No, Cinitapride + Pantoprazole is not a steroid. This combination is made up of two active ingredients, Cinitapride, a gastroprokinetic agent, and Pantoprazole, a proton pump inhibitor (PPI). These are used to manage gastroesophageal reflux disease (GERD) and peptic ulcer disease.
Does Cinitapride + Pantoprazole have any effect on sleep?
Cinitapride + Pantoprazole is not commonly known to directly affect sleep. However, Cinitapride, a prokinetic, may cause side effects like drowsiness in some individuals. If you notice changes in your sleep pattern while using these medications, it's advisable to consult your doctor for further guidance.
Will Cinitapride + Pantoprazole affect fertility?
This combination is not generally associated with affecting fertility. However, if you have specific concerns or underlying conditions, it's best to discuss them with your doctor for personalized advice.
Is it safe to take Cinitapride + Pantoprazole daily?
Yes, it is safe to take Cinitapride + Pantoprazole daily as per the prescription provided by your doctor. It is important not to self-medicate and follow the dosage instructions given by your doctor closely.
How much time does Cinitapride + Pantoprazole take to work?
The time taken for Cinitapride + Pantoprazole to show its effects can vary from person to person as it depends on various factors such as the severity of the disease, individual patient response, and other health conditions. Please consult your doctor for specific information related to your treatment.
What is the best time to take Cinitapride + Pantoprazole?
Cinitapride + Pantoprazole is usually prescribed to be taken 30-60 minutes before a meal, typically breakfast. However, the timing can vary based on your specific medical condition and your doctor's advice.
Can Cinitapride + Pantoprazole cause weight gain?
No, weight gain is not a common side effect of Cinitapride + Pantoprazole. However, if you notice unusual weight gain, consult your doctor.
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