Cisapride + Simethicone

Dosage Forms Available

• Cisapride + Simethicone is available in oral tablet and oral suspension forms.

Age and Dose Restrictions

• Cisapride + Simethicone is recommended for use primarily by adults. It is not recommended for children.

Contraindications

• This combination is contraindicated in individuals with complete mechanical gastrointestinal obstruction.

• It is also contraindicated in people with severe respiratory disorders.

• Individuals with known hypersensitivity to any of the components should avoid using it.

Other Medications to Avoid

• This combination may interact with antibiotics (such as erythromycin and clarithromycin), antifungals (like ketoconazole and itraconazole), antiarrhythmics (such as quinidine and sotalol), antidepressants (like citalopram, tricyclics), anti-psychotics (like thioridazine, ziprasidone), antihistamines (such as astemizole, terfenadine), and HIV protease inhibitors (like ritonavir).

Overdose and Missed Dose

• Symptoms of overdose might include severe nausea, vomiting, diarrhoea, abdominal cramps, drowsiness, fainting, and disturbed heart rhythm. If an overdose is suspected, seeking emergency medical care is crucial.

• If a dose is missed, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed one. Do not take a double dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For mild nausea or headaches, consider taking the combination with food or adjusting the timing of doses.

• Increasing fluid intake may help alleviate mild constipation associated with this combination.

Use in Driving and Operating Machinery

• Cisapride + Simethicone can cause dizziness or drowsiness in some individuals. It is advisable to avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

• The safety of Cisapride + Simethicone during pregnancy and lactation has not been fully established. It should only be used if the potential benefits justify the potential risk to the foetus or infant. Always consult your doctor before using this combination during pregnancy or while breastfeeding.

Caution in Other Conditions

• Caution is advised when using Cisapride + Simethicone in patients with a history of heart disease or abnormal heart rhythms.

• Patients with kidney or liver impairment should also use this medication cautiously.

Special Dietary and Lifestyle Recommendations

• To manage symptoms of gastrointestinal discomfort such as bloating and indigestion, consider eating smaller, more frequent meals instead of three large meals a day.

• Avoid foods that are known to increase gas production like beans, cabbage, and onions.

• Staying hydrated by drinking plenty of water can aid digestion and help manage symptoms of indigestion.