Citric Acid + Potassium is used primarily for long-term management of conditions requiring alkaline urine, such as uric acid and cystine kidney stones, gout, renal tubular acidosis, and chronic metabolic acidosis caused by kidney disease. This medicine belongs to the group of urinary alkalinizers.
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Citric Acid + Potassium is a urinary alkalinizer combination.
Citric Acid, upon administration, dissociates to release citrate ions. The citrate ions are filtered by the kidneys and act to increase the urine pH by accepting protons. This leads to alkaline urine, which helps in preventing the crystallisation of uric acid and cystine, thereby inhibiting stone formation.
Potassium also dissociates after administration to release potassium ions. These ions serve to correct any potassium deficits in the body, and also help to avoid sodium overload. The overall effect is a maintained balance of bodily electrolytes, further contributing to the prevention of stone formation.
Thus, the combination of Citric Acid + Potassium effectively increases the pH of urine, helping to prevent conditions like uric acid and cystine kidney stones, gout and certain forms of metabolic acidosis associated with kidney disease.
Doctor of Medicine
BMS, FMC, MD Resident
Citric Acid + Potassium is available for oral use in the form of a liquid solution or as capsules or tablets.
This combination is intended for use by adults and children, although specific paediatric dosage adjustments and precautions may apply.
This combination is contraindicated for patients with known allergic reactions to any of its components.
The medicine is also contraindicated in severe renal failure, untreated Addison's disease, severe dehydration, active peptic ulcers, gastrointestinal bleeding, hypoparathyroidism, osteomalacia, and hypercalciuria.
This combination may interact with medications like lithium, digoxin, and anti-arrhythmics (such as amiodarone and sotalol), affecting their toxicity. It may also reduce the effect of uricosuric medications like probenecid and increase potassium retention when used with potassium-sparing diuretics (such as spironolactone), ACE inhibitors (like lisinopril), or ARBs (such as losartan). Additionally, it can increase the risk of milk-alkali syndrome when taken with calcium supplements and absorbable antacids.
Overdosage of this combination may lead to symptoms such as confusion, muscle weakness, irregular heartbeat, irritability, twitching and tetany. If you observe any of these symptoms, consult your doctor immediately.
If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to catch up.
Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Taking the combination after meals can help manage gastrointestinal intolerances like abdominal discomfort, nausea, diarrhoea and vomiting.
Drinking plenty of fluids can help manage side effects like gastro-oesophageal reflux.
This combination does not typically affect your ability to drive or operate machinery. However, if you experience side effects like confusion, muscle weakness or an irregular heartbeat, avoid such activities and consult your doctor.
The safety of Citric Acid + Potassium during pregnancy or lactation has not been fully established. Therefore, it should only be used if clearly needed and prescribed by a doctor.
Patients with renal impairment need to exercise caution when using Citric Acid + Potassium due to its effects on electrolyte balance and potential for altering kidney function.
Individuals with heart conditions should also be cautious because of the potential for inducing hyperkalaemia.
Regularly check your body weight, as sudden weight gain may indicate water retention.
Increase fluid intake to help dilute urine and prevent stone formation.
Adopt a diet low in sodium and animal proteins while increasing intake of fruits and vegetables to help maintain an alkaline urine pH.
Avoid foods high in oxalates, such as spinach, rhubarb, nuts, and tea, if prone to oxalate stones.
Frequently asked questions
No, it is not a steroid. It is a medication that belongs to the class of urinary alkalinizers used primarily to manage conditions that require a long-term alkaline urine pH.
There is no evidence to suggest that it directly affects sleep patterns. However, if you experience sleep disturbances, consult your doctor, as it could be related to underlying conditions or other medications.
There are no known direct effects of this combination on fertility. However, it is always advisable to discuss any concerns regarding fertility with your doctor before starting any new medication.
There are no specific dietary restrictions while taking this combination unless advised by your doctor. A balanced and nutritious diet is generally beneficial for overall health.
The safety of daily use of this combination depends on the individual's health condition and the dose prescribed by the doctor. Follow your doctor's advice regarding the duration of therapy.
It starts working soon after intake, but the overall effect depends on the individual’s health condition and the underlying problem being managed. Always consult with your doctor for more information.
It can be taken at any time of the day, as advised by your doctor. However, doses are often taken after meals to minimise gastrointestinal discomfort.
Citric Acid + Potassium in other salts
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