Clotrimazole + Tinidazole

Dosage Forms Available

• Clotrimazole + Tinidazole is available for use via vaginal route in the form of cream and tablet (usually inserted into the vagina using an applicator), composition suppositories.

Age and Dose Restrictions

• This combination medication is intended for use in adults aged 18 and above.

• Use in children is generally not recommended without medical advice.

Contraindications

• The use of Clotrimazole + Tinidazole is contraindicated in patients with known hypersensitivity to either clotrimazole or tinidazole.

• It is also contraindicated in patients with a history of hypersensitivity to other azole antifungals or nitroimidazole antibiotics.

Other Medications to Avoid

• This combination may interact with anticoagulants (such as warfarin), immunosuppressants (like cyclosporine and tacrolimus), anti-seizure medications (including phenytoin), and antacid (like cimetidine).

Overdose and Missed Dose

• An overdose may cause severe nausea, vomiting, stomach pain, an irregular heartbeat, and seizures. If you suspect an overdose, contact a healthcare professional immediately.

• If you forget a dose of this medicine, use it as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Resting or sleeping in a dark, quiet room can help alleviate headaches.

• Avoiding spicy or fatty foods may help manage an upset stomach or diarrhoea.

Use in Driving and Operating Machinery

• Clotrimazole + Tinidazole may cause dizziness or sleepiness. If you experience these side effects, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• The use of Clotrimazole + Tinidazole during pregnancy or lactation should only be done under the advice and supervision of a doctor.

Caution in Other Conditions

• Patients with liver disease should exercise caution when using Clotrimazole + Tinidazole as it can cause liver damage. Regular monitoring of liver function may be necessary.

• Caution is advised in patients with blood disorders as this medication can cause a decrease in white blood cells, leading to a higher risk of infections.

Special Dietary and Lifestyle Recommendations

• Maintain good hygiene to prevent the recurrence of vaginal infections.

• Wear cotton underwear and avoid tight-fitting pants or jeans to allow air circulation.

• Avoid using scented soaps, lotions, or other products in the vaginal area that can disrupt the natural balance of bacteria and fungi.