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Conjugated Estrogen

Uses of Conjugated Estrogen

  • Conjugated Estrogen is primarily used to manage symptoms of menopause, such as hot flashes and vaginal dryness, and it is part of the group of oestrogen hormone replacement therapies.

  • This medicine is also used to prevent osteoporosis after menopause, treat certain types of prostate and breast cancer, and manage conditions like hypogonadism and certain cases of primary ovarian failure where there is a deficiency of oestrogen.

Side effects of Conjugated Estrogen

  • Breast tenderness or enlargement

  • Headaches

  • Nausea and vomiting

  • Bloating and abdominal cramps

  • Mood changes and irritability

How Conjugated Estrogen works

  • Conjugated Estrogen is an oestrogen hormone replacement medicine.

  • It works by replenishing the reduced levels of oestrogen in the body, primarily mimicking the role of estradiol.

  • Conjugated Estrogen binds to estrogen receptors when administered, promoting the growth and maintenance of the female reproductive system and other tissues that respond to oestrogen.

  • In bones, it reduces bone resorption, increasing bone mineral density.

  • At high doses, it can suppress the growth of hormone-sensitive breast and prostate cancers by decreasing hormone receptors.

Certified content

Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • Conjugated Estrogen is available in the form of oral tablets that are taken by mouth.

  • It is also available as a topical vaginal cream, which is applied directly inside the vagina.

Age and Dose Restrictions

  • This medicine is meant for use by adult women, particularly those who are post-menopausal.

  • It is also used in men of adult age for specific conditions as prescribed by a doctor.

Contraindications

  • Conjugated Estrogen should not be used for any of its components in patients with known allergies.

  • It is also contraindicated in individuals with active or recent thromboembolic disease and those with active or chronic liver dysfunction or disease.

Other Medications to Avoid

  • Conjugated Estrogen may interact with CYP3A4 inhibitors (such as clarithromycin), CYP3A4 inducers (such as carbamazepine), thyroid hormone replacement therapy, and corticosteroids (like prednisone and dexamethasone).

  • Always consult your doctor before starting any new medication while on Conjugated Estrogen treatment.

Overdose and Missed Dose

  • Overdose of Conjugated Estrogen can lead to severe nausea, vomiting, or tenderness in the abdominal region. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, please consult your doctor if you experience severe side effects or worsening symptoms.

  • Drinking plenty of water can help manage nausea and bloating.

  • Rest can help manage headaches or mood changes.

  • Wearing loose, comfortable clothing can help manage breast tenderness or enlargement.

Use in Driving and Operating Machinery

  • Conjugated Estrogen may cause dizziness or blurred vision. If you experience these effects, avoid driving or operating heavy machinery until the effects have worn off.

Use in Pregnancy and Lactation

  • Conjugated Estrogen is not recommended for use during pregnancy. If you are breastfeeding, consult your doctor before starting this medicine.

Caution in Other Conditions

  • Patients with a history of thromboembolic disorders, breast or uterine cancer, liver problems, or high levels of triglycerides should exercise caution when taking Conjugated Estrogen.

Special Dietary and Lifestyle Recommendations

  • Maintain a balanced diet of calcium and vitamin D to support bone health.

  • Regular mild to moderate exercise can help maintain overall health and reduce menopausal symptoms such as hot flashes.

  • Avoid smoking, as it increases the risk of serious cardiovascular side effects when using Conjugated Estrogen.

  • Regular check-ups are essential when using this medication, including breast exams and mammograms for early detection of potential complications.

Frequently asked questions

Weight changes, which could include either weight gain or weight loss, are one potential side effect of taking Conjugated Estrogen. However, this effect may not be experienced by everyone using the medicine.

Yes, Conjugated Estrogen is derived from the urine of pregnant mares or horses. The oestrogen hormones found in horse urine closely mimic the hormones naturally produced by humans.

There is no mention of withdrawal symptoms in the available research data. However, it is best to consult your doctor before stopping any medication to understand and manage potential effects.

Yes, online consultations with a qualified doctor can enable you to get a prescription for medicines like Conjugated Estrogen. However, it is important to have an in-person consultation with your doctor whenever possible for thorough health evaluations.

While some natural supplements may not interfere with Conjugated Estrogen, there could be potential interactions with others, and it is best to consult your doctor before starting any new supplement regimen.

In specific cases, doctors may prescribe Conjugated Estrogen to men for managing certain advanced prostate cancers. However, this should only be done under strict medical supervision.

Smoking while taking medicines like Conjugated Estrogen can increase the risk of serious cardiovascular side effects and could also potentially affect the effectiveness of the medicine.

Terms & Conditions

Available medicines for CONJUGATED ESTROGEN
Estrin Tablet 10
Estrin Tablet 10
Cipla Ltd.
Pack of 10 Units
₹57.40
MRP ₹70.00
18.00% OFF
Premarin Vaginal Cream 14gm
Premarin Vaginal Cream 14gm
Pfizer Ltd
Pack of 14 GM
₹426.10
MRP ₹519.64
18.00% OFF
Conjya 0.625 MG Tablet 28
Conjya 0.625 MG Tablet 28
West-coast Pharmaceutical Works Ltd
Pack of 28 Units
₹401.80
MRP ₹490.00
18.00% OFF
Conjya 1.25 MG Tablet 28
Conjya 1.25 MG Tablet 28
West-coast Pharmaceutical Works Ltd
Pack of 28 Units
₹697.00
MRP ₹850.00
18.00% OFF
Premarin 0.3mg Tablet 28
Premarin 0.3mg Tablet 28
Pfizer Ltd
Pack of 28 Units
₹797.29
MRP ₹972.31
18.00% OFF
Premarin 0.625mg Tablet 28
Premarin 0.625mg Tablet 28
Pfizer Ltd
Pack of 28 Units
₹1029.95
MRP ₹1256.04
18.00% OFF
Premarin 1.25 MG Tablet 28
Premarin 1.25 MG Tablet 28
Pfizer Ltd
Pack of 28 Units
₹218.70
MRP ₹266.71
18.00% OFF
Conjumed 5 MG Tablet 28
Conjumed 5 MG Tablet 28
West-coast Pharmaceutical Works Ltd
Pack of 28 Units
₹491.18
MRP ₹599.00
18.00% OFF

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