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Cyproterone + Ethinyl Estradiol

Uses of Cyproterone + Ethinyl Estradiol

  • Cyproterone + Ethinyl Estradiol is primarily used to manage moderate to severe acne related to androgen sensitivity and excessive hair growth (hirsutism) in women of reproductive age. It belongs to the class of anti-androgen and estrogen combination medicines.

  • It can also be prescribed to manage symptoms of polycystic ovary syndrome (PCOS) such as irregular periods, acne, and excess hair growth, and as a contraceptive.

Side effects of Cyproterone + Ethinyl Estradiol

  • Nausea

  • Headaches

  • Breast tenderness

  • Weight changes

  • Mood changes

How Cyproterone + Ethinyl Estradiol works

  • Cyproterone + Ethinyl Estradiol is a hormonal combination medicine.

  • Cyproterone is an anti-androgen. It works by attaching itself to androgen receptors in the body, blocking the effect of androgens. This decreases symptoms like acne and excessive hair growth which are related to high levels of androgens.

  • Ethinyl Estradiol is a synthetic form of the hormone oestrogen. It enhances the effectiveness of Cyproterone by increasing the production of a certain protein that binds to androgens, further reducing their activity. In addition, it prevents ovulation, providing contraceptive effects.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Cyproterone + Ethinyl Estradiol is available for use as oral tablets.

Age and Dose Restrictions

  • This medicine is prescribed for women of reproductive age and is not recommended for use in children or men.

Contraindications

  • Cyproterone + Ethinyl Estradiol is contraindicated in women who are pregnant or breastfeeding, smoke and are over 35 years old, have a history of blood clots, stroke, or heart attack, have severe liver disease, have certain types of migraine, have or have had breast cancer or other estrogen-sensitive cancers, and have undiagnosed vaginal bleeding.

Other Medications to Avoid

  • Cyproterone + Ethinyl Estradiol may interact with certain antibiotics (such as rifampicin and griseofulvin), anticonvulsants (like phenytoin, carbamazepine and phenobarbital), and HIV medications (such as ritonavir), and herbal supplements like St. John's Wort.

Overdose and Missed Dose

  • An overdose of Cyproterone + Ethinyl Estradiol may result in nausea, vomiting, breast tenderness, dizziness, fatigue and withdrawal bleeding. If you experience any of these symptoms, consult your doctor immediately.

  • If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for a missed one.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of fluids can help manage side effects such as nausea.

  • To manage headaches, try resting and taking a break from your regular activities.

  • If you experience mood changes, try to rest and relax.

Use in Driving and Operating Machinery

  • Cyproterone + Ethinyl Estradiol may cause dizziness or fatigue. If you experience these side effects, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • Cyproterone + Ethinyl Estradiol is not recommended during pregnancy or breastfeeding. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medication.

Caution in Other Conditions

  • Women with a history of liver disease or cancer should use Cyproterone + Ethinyl Estradiol with caution. Also, women with a history of blood clots or stroke should consult their doctor before using this medication.

Special Dietary and Lifestyle Recommendations

  • Aim to maintain a healthy weight as being overweight can increase the risk of side effects.

  • Include plenty of fruits and vegetables in your diet to keep your skin healthy.

  • Limit alcohol consumption as it can increase the risk of side effects.

Frequently asked questions

Yes, Cyproterone + Ethinyl Estradiol is a combination of two hormones-cyproterone, an anti-androgen, and ethinyl estradiol, a form of oestrogen, both of which are types of steroids.

There is no direct evidence to suggest that Cyproterone + Ethinyl Estradiol impacts sleep. However, changes in hormone levels can sometimes indirectly influence sleep patterns. If you notice any significant changes in your sleep, consult your doctor.

Cyproterone + Ethinyl Estradiol has contraceptive effects and prevents ovulation. Thus, it can affect fertility during its use. However, normal fertility is expected to return after discontinuation of the medication.

No specific dietary restrictions are mentioned in conjunction with the use of Cyproterone + Ethinyl Estradiol. However, maintaining a balanced diet is always beneficial for overall health.

Yes, it is safe to take Cyproterone + Ethinyl Estradiol daily as prescribed by your doctor for the treatment of conditions like acne or hirsutism or as a contraceptive.

Improvements in conditions like acne are usually seen after about 3 months of consistent use. Maximum benefits are seen after about 6 months.

Cyproterone + Ethinyl Estradiol is a prescription medication and is not available over the counter.

Terms & Conditions


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