Dapagliflozin + Linagliptin + Metformin

Expert Advice

Dosage Forms Available

• Dapagliflozin + Linagliptin + Metformin is available in tablet form for oral administration.

Age and Dose Restrictions

• This medicine is meant for use in adults only.

Contraindications

• Dapagliflozin + Linagliptin + Metformin is contraindicated in patients with severe renal impairment or end-stage renal disease.

• It is also contraindicated for individuals undergoing dialysis or with a history of serious hypersensitivity reactions to any of its components.

• Patients with acute or chronic metabolic acidosis, including diabetic ketoacidosis, should not take this medicine.

Other Medications to Avoid

• This medicine may interact with diuretics (eg., furosemide and hydrochlorothiazide), antihypertensive medicines (eg., lisinopril and amlodipine), strong P-glycoprotein or CYP3A4 inducers (eg., rifampin and carbamazepine), cationic medicines (eg., amiloride and digoxin), and iodinated contrast agent.

Overdose and Missed Dose

• An overdose of Dapagliflozin + Linagliptin + Metformin may lead to lactic acidosis, characterised by nausea, vomiting, respiratory distress, and abdominal pain. Immediate medical attention is needed if you suspect an overdose.

• If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Avoid repeating the doses.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage gastrointestinal side effects like nausea or abdominal discomfort, consider taking your medication with a substantial meal.

• Ensure adequate hydration to help manage possible urinary tract infections or dehydration-related effects.

Use in Driving and Operating Machinery

• Dapagliflozin + Linagliptin + Metformin generally does not impact the ability to drive or operate machinery. However, be cautious of potential dizziness due to fluctuations in blood glucose levels.

Use in Pregnancy and Lactation

• The safety of Dapagliflozin + Linagliptin + Metformin during pregnancy and lactation has not been established. Use of this medicine during these periods is not recommended unless directed by a doctor. Consult your doctor for advice on managing diabetes if you are pregnant or breastfeeding.

Caution in Other Conditions

• Caution should be exercised when using Dapagliflozin + Linagliptin + Metformin in patients with liver conditions as it may affect medicine metabolism and efficacy.

• Patients at risk for volume depletion or hypotension should be monitored closely due to the diuretic effect of dapagliflozin.

Special Dietary and Lifestyle Recommendations

• Adhere to a balanced diet low in simple sugars and high in fibre to help manage blood glucose levels effectively while taking Dapagliflozin + Linagliptin + Metformin.

• Regular physical activity can help enhance the effectiveness of this medication in managing type 2 diabetes.

• Monitoring carbohydrate intake is crucial; consider consulting a dietician for personalised advice.

• Stay hydrated especially since dapagliflozin can increase urination which may lead to dehydration.

• Regular monitoring of blood sugar levels is recommended to adjust dietary intake and medication doses accurately.

Frequently asked questions

Terms & Conditions