Diclofenac + Nimesulide

Dosage Forms Available

• Diclofenac + Nimesulide can be taken orally (tablet and oral suspension).

Age and Dose Restrictions

• Diclofenac + Nimesulide is primarily intended for use in adults aged 18 and older.

Contraindications

• Diclofenac + Nimesulide is contraindicated in individuals who have previously had allergic reactions to either diclofenac, nimesulide or any other NSAIDs. It should not be taken by individuals who have active peptic ulcer disease or gastrointestinal bleeding. People with severe heart failure, significant hepatic impairment or renal impairment should also avoid this medication.

Other Medications to Avoid

• This combination may interact with anticoagulants (such as warfarin), other NSAIDs (like ibuprofen), diuretics (such as furosemide), and ACE inhibitors (like ramipril).

Overdose and Missed Dose

• Overdosing on Diclofenac + Nimesulide may lead to nausea, vomiting, abdominal pain, dizziness or even more serious conditions. If you think you may have overdosed, it is important to contact your doctor immediately.

• If you miss a dose of Diclofenac + Nimesulide, take it as soon as you remember. However, skip the missed dose if it is nearly time for your next dose. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For nausea or upset stomach, try taking this medicine with food.

• Sipping on water more often may help manage dry mouth.

• Dizziness or light-headedness may be managed by getting up slowly when rising from a sitting or lying position.

Use in Driving and Operating Machinery

• Diclofenac + Nimesulide may cause dizziness or drowsiness in some individuals. If you feel dizzy or drowsy after taking this medication, it is advised to avoid driving or operating heavy machinery until these effects subside.

Use in Pregnancy and Lactation

• Always consult your doctor before taking this medication if you are pregnant, planning to become pregnant or are breastfeeding.

Caution in Other Conditions

• Individuals with mild to moderate hepatic impairment or renal impairment should use Diclofenac + Nimesulide with caution and under a doctor's supervision.

• Patients with cardiovascular disease also need to exercise caution while using this medication due to the increased risk of thrombotic events.

Special Dietary and Lifestyle Recommendations

• Regularly monitor your blood pressure as NSAIDs can lead to elevated blood pressure.

• Practise good dental hygiene as this medicine may cause dry mouth which can lead to dental problems.