Diclofenac + Trypsin-chymotrypsin

Dosage Forms Available

• Diclofenac + Trypsin-Chymotrypsin is available for oral administration as enteric-coated tablets, which should be swallowed whole with water.

Age and Dose Restrictions

• This combination medication is primarily intended for adult usage. It is not generally recommended for children unless specifically prescribed by a doctor.

Contraindications

• Diclofenac + Trypsin-Chymotrypsin is contraindicated in patients with known hypersensitivity to any of its ingredients, active peptic ulcers or gastrointestinal bleeding, severe liver or kidney impairment, and those with a history of asthma or allergic reactions triggered by nonsteroidal anti-inflammatory drugs (NSAIDs).

Other Medications to Avoid

• This combination may interact with anticoagulants (such as warfarin), antiplatelet medicines (like aspirin and clopidogrel), diuretics (like furosemide), mood stabilisers (lithium), immunosuppressants (such as methotrexate and cyclosporine), and other NSAIDs (naproxen) and antihypertensive medicines (like atenolol). Interaction with these medications can alter their effects or increase the risk of side effects. Always consult your doctor before starting any new medications.

Overdose and Missed Dose

• An overdose of Diclofenac + Trypsin-Chymotrypsin can lead to severe gastrointestinal symptoms, drowsiness, dizziness, tinnitus, and hypotension. Immediate medical attention should be sought in case of a suspected overdose.
• If you forget to take a dose of this medication, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose entirely. Do not double the dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

• Drinking plenty of water can help alleviate some common side effects such as dizziness and headaches.
• Taking the medication with food or milk can reduce gastrointestinal side effects like abdominal pain and nausea.

Use in Driving and Operating Machinery

• Diclofenac + Trypsin-Chymotrypsin may cause dizziness and affect your ability to concentrate. Therefore, it is advised to avoid driving and operating heavy machinery until you know how the medication affects you.

Use in Pregnancy and Lactation

• This medication should be used during pregnancy only if the potential benefits justify the potential risks to the foetus. It is contraindicated in the third trimester as it may delay labour and cause foetal harm. Breastfeeding mothers should also consult their doctor before using this medicine.

Caution in Other Conditions

• Patients with liver, kidney, or heart diseases should exercise caution while taking Diclofenac + Trypsin-Chymotrypsin. It may increase the risk of gastrointestinal ulceration and bleeding, cause fluid retention, oedema, and hypertension, and increase the risk of cardiovascular thrombotic events.

Special Dietary and Lifestyle Recommendations

• A balanced diet rich in fruits, vegetables, lean proteins, whole grains, and low-fat dairy can help manage inflammatory conditions like arthritis.
• Regular physical activity can also help manage inflammatory conditions and improve joint health. However, it is important to avoid strenuous exercises that can worsen joint pain.
• Reducing stress through activities like meditation, yoga, or deep breathing exercises can also be beneficial.
• Avoid smoking and limit alcohol consumption as they can exacerbate inflammation.