Difluprednate

Dosage Forms Available

• Difluprednate can be applied topically (ophthalmic emulsion).

Age and Dose Restrictions

• This medicine is primarily prescribed for adults.

Contraindications

• Difluprednate is contraindicated in individuals with most active viral diseases of the cornea and conjunctiva, such as epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, and mycobacterial or fungal infections of the eye. Patients with known hypersensitivity to Difluprednate or any other components of the formulation should avoid using this medication.

Other Medications to Avoid

• Difluprednate may interact with other corticosteroids (e.g., prednisolone, hydrocortisone), antiglaucoma medications (e.g., timolol, brimonidine) and nonsteroidal anti-inflammatory medicines (NSAIDs) (e.g., ibuprofen, naproxen).

Overdose and Missed Dose

• In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.
• If you miss a dose, administer it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage dryness or irritation in the eyes, apply a warm compress and stay away from smoke, dust, and other potential irritants.
• Taking rest and avoiding activities that strain the eyes may help manage eye pain or discomfort.

Use in Driving and Operating Machinery

• Difluprednate can cause blurred vision temporarily. If you experience this side effect, avoid driving or operating heavy machinery until your vision clears.

Use in Pregnancy and Lactation

• Difluprednate should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. Consult your doctor before using this medicine while breastfeeding.

Caution in Other Conditions

• Regular monitoring of intraocular pressure is necessary, if Difluprednate is used for 10 days or longer, due to the risk of glaucoma from prolonged use.
• Patients with a history of ocular herpes simplex should exercise caution when using Difluprednate as it may prolong and exacerbate the severity of many viral eye infections.

Special Dietary and Lifestyle Recommendations

• Wearing protective sunglasses can aid in reducing discomfort caused by light sensitivity.
• Follow the 20-20-20 rule by taking a break every 20 minutes to look at something 20 feet away for 20 seconds, especially if you use screens frequently.
• Do not wear contact lenses while using Difluprednate unless your doctor advises otherwise.