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Dipyridamole

Uses of Dipyridamole

  • The main use of Dipyridamole is to prevent blood clots and reduce the risk of stroke. It belongs to the group of antiplatelet medicines.

  • Additionally, it is used in patients with prosthetic heart valves or those who have undergone cardiac surgery to prevent thromboembolism. It is also used in conjunction with aspirin for patients with a history of transient ischemic attack (TIA) or ischemic stroke and as an adjunct to warfarin therapy to prevent thrombosis.

Side effects of Dipyridamole

  • Headache

  • Dizziness

  • Nausea and vomiting

  • Abdominal pain

  • Rash

How Dipyridamole works

  • Dipyridamole is an antiplatelet medication.

  • It works primarily by inhibiting adenosine reuptake, leading to an increase in extracellular adenosine levels. This results in the activation of adenosine receptors, which helps to inhibit platelet aggregation and vasodilation. Additionally, dipyridamole has vasodilatory effects by inhibiting the enzyme phosphodiesterase, leading to increased levels of cyclic AMP in platelets and endothelial cells, further contributing to its antiplatelet and vasodilatory actions.

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Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Dipyridamole is available for use orally in the form of tablets.

Age and Dose Restrictions

  • This medicine is meant for use by adults and is not typically prescribed for children.

Contraindications

  • Dipyridamole is contraindicated in patients with known hypersensitivity to any of its components.

  • It is also contraindicated in individuals with active peptic ulcer disease and in those who have severe coronary artery disease or have recently suffered a myocardial infarction.

Other Medications to Avoid

  • Dipyridamole may interact with anticoagulants (such as warfarin, dabigatran), antiplatelet medications (such as clopidogrel, aspirin), blood pressure-lowering medicines (such as amlodipine, lisinopril), and medications affecting liver enzymes (such as rifampin, ketoconazole). It can also interact with vasodilators (such as nitroglycerin, hydralazine).

Overdose and Missed Dose

  • An overdose of Dipyridamole may lead to severe hypotension, tachycardia, flushing, sweating, and dizziness. Immediate medical attention is necessary, focusing on supportive measures such as fluid replacement and possibly vasopressor therapy if required.

  • If you forget to take a dose of this medicine, take it as soon as you remember unless it is nearly time for your next dose. In that case, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For headaches, consider taking the medication at a different time of day.

  • Ensure adequate hydration by drinking plenty of water, which might help ease nausea.

Use in Driving and Operating Machinery

  • This medication may impair your ability to drive or operate machinery. If you experience dizziness or light-headedness after taking Dipyridamole, avoid engaging in such activities.

Use in Pregnancy and Lactation

  • Consult your doctor before using Dipyridamole during pregnancy and lactation. The safety of this medicine for use during pregnancy or while breastfeeding has not been fully established.

Caution in Other Conditions

  • Individuals with severe liver or kidney impairment should use Dipyridamole with caution due to potential alterations in medicinal metabolism and elimination.

  • Those with unstable angina or other acute cardiac conditions should be closely monitored due to the risk of exacerbating their condition.

Special Dietary and Lifestyle Recommendations

  • Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins to support overall cardiovascular health.

  • Limit intake of foods high in saturated fats and cholesterol to help manage blood lipid levels.

  • Regular moderate-intensity exercise like brisk walking or cycling is recommended unless otherwise advised by your doctor.

  • Avoid excessive caffeine consumption as it may interfere with the effects of Dipyridamole.

  • Smoking cessation is crucial; seek support groups or cessation programs if needed.

  • Maintain regular follow-ups with your doctor to monitor your health condition and the effectiveness of the treatment with Dipyridamole.

Frequently asked questions

No, Dipyridamole is not a steroid. It is an antiplatelet medicine that helps prevent blood clots.

There is no reported evidence to suggest that Dipyridamole directly impacts your sleep. However, if you experience any unusual sleep-related symptoms, consult your doctor.

There are no known effects of Dipyridamole on fertility. If you have concerns regarding this, it is recommended to consult your doctor.

No specific diet restrictions are known while taking Dipyridamole. As always, a balanced diet is recommended when taking any medicine.

Dipyridamole should be taken as prescribed by your doctor. It is typically safe for daily use when taken as directed.

The time taken for Dipyridamole to show its effect can vary depending on the individual and the condition being managed.

Dipyridamole usually requires a prescription and is not typically available over the counter.

Terms & Conditions


Dipyridamole in other salts

Available medicines for DIPYRIDAMOLE
Thrombonil 100 MG Tablet 10
Thrombonil 100 MG Tablet 10
Ranbaxy Laboratories Ltd
Pack of 10 Units
₹9.36
MRP ₹11.42
18.00% OFF
Persantin 25 MG Tablet 10
Persantin 25 MG Tablet 10
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Pack of 10 Units
₹10.46
MRP ₹12.75
18.00% OFF
Cardiwell 75 MG Tablet 10
Cardiwell 75 MG Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹6.48
MRP ₹7.90
18.00% OFF
Cardiwell 100 MG Tablet 10
Cardiwell 100 MG Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹8.00
MRP ₹9.76
18.00% OFF
Persantin 100 MG Tablet 10
Persantin 100 MG Tablet 10
Zydus Cadila
Pack of 10 Units
₹31.09
MRP ₹37.92
18.00% OFF

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