Domperidone + Lansoprazole

Dosage Forms Available

• Domperidone + Lansoprazole is available for oral administration in the form of tablets, capsules and oral suspension.

Age and Dose Restrictions

• This combination medicine is meant for use in adults and children aged over 12 years.

Contraindications

• Domperidone + Lansoprazole is contraindicated in patients with known allergies to either domperidone or lansoprazole.

• It is also contraindicated for patients with a history of gastrointestinal bleeding, mechanical intestinal obstruction, severe liver disease, pheochromocytoma, or cardiac disorders such as QT prolongation or ventricular arrhythmia.

Other Medications to Avoid

• This combination can interact with antifungal medications (such as ketoconazole), macrolide antibiotics (like erythromycin) and certain antiviral medications used to treat HIV/AIDS (such as ritonavir).

Overdose and Missed Dose

• An overdose may result in symptoms such as diarrhoea, muscle spasms, irregular heartbeat, and seizures. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take double doses to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing Domperidone + Lansoprazole. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

• Drinking plenty of fluids may help manage the side effects of diarrhoea and dry mouth.

• Taking the medication with meals can help minimise stomach-related side effects like nausea and stomach pain.

Use in Driving and Operating Machinery

• This combination may cause dizziness or sleepiness in some individuals. If you experience these side effects, avoid driving or operating heavy machinery until you are sure it does not affect your ability to do so safely.

Use in Pregnancy and Lactation

• The safety of Domperidone + Lansoprazole during pregnancy and lactation is not well established. It's advised to consult your doctor before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Caution in Other Conditions

• Patients with liver disease or heart conditions should exercise caution while taking Domperidone + Lansoprazole. Regular monitoring by a doctor may be necessary in such cases.

• This medication should be used with caution in patients with underlying electrolyte imbalances as it can cause changes in potassium and magnesium levels in the blood.

Special Dietary and Lifestyle Recommendations

• Regularly drinking water throughout the day can aid digestion and alleviate some gastrointestinal symptoms associated with this medication.

• Incorporating regular physical activity into your daily routine could potentially help improve gastrointestinal motility.