Domperidone + Lansoprazole
Uses of Domperidone + Lansoprazole
Domperidone + Lansoprazole is primarily used to manage various gastrointestinal conditions and belongs to the class of anti-nausea, gastric motility medicines, and proton pump inhibitors.
Secondary uses include the management of symptoms like heartburn, acid reflux, nausea, vomiting, and stomach pain associated with conditions such as Gastroesophageal reflux disease (GERD), Peptic ulcers, Gastrointestinal motility disorders, and Zollinger-Ellison syndrome.
Side effects of Domperidone + Lansoprazole
Headache
Dizziness
Diarrhoea
Stomach pain
Dry mouth
How Domperidone + Lansoprazole works
Domperidone is a dopamine antagonist. It works by blocking the action of dopamine, a natural substance in your body. This helps speed up the process of moving food through your stomach and gut, which can help prevent you from feeling sick or being sick.
Lansoprazole is a proton pump inhibitor. It reduces the amount of acid produced in your stomach by blocking an enzyme, found on the stomach lining, that 'pumps' acid into the stomach. Together, these medicines work synergistically to manage symptoms associated with certain gastrointestinal disorders such as gastroesophageal reflux disease (GERD) and peptic ulcers.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Domperidone + Lansoprazole is available for oral administration in the form of tablets, capsules and oral suspension.
Age and Dose Restrictions
This combination medicine is meant for use in adults and children aged over 12 years.
Contraindications
Domperidone + Lansoprazole is contraindicated in patients with known allergies to either domperidone or lansoprazole.
It is also contraindicated for patients with a history of gastrointestinal bleeding, mechanical intestinal obstruction, severe liver disease, pheochromocytoma, or cardiac disorders such as QT prolongation or ventricular arrhythmia.
Other Medications to Avoid
This combination can interact with antifungal medications (such as ketoconazole), macrolide antibiotics (like erythromycin) and certain antiviral medications used to treat HIV/AIDS (such as ritonavir).
Overdose and Missed Dose
An overdose may result in symptoms such as diarrhoea, muscle spasms, irregular heartbeat, and seizures. If you suspect an overdose, seek immediate medical attention.
If you miss a dose take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take double doses to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing Domperidone + Lansoprazole. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.
Drinking plenty of fluids may help manage the side effects of diarrhoea and dry mouth.
Taking the medication with meals can help minimise stomach-related side effects like nausea and stomach pain.
Use in Driving and Operating Machinery
This combination may cause dizziness or sleepiness in some individuals. If you experience these side effects, avoid driving or operating heavy machinery until you are sure it does not affect your ability to do so safely.
Use in Pregnancy and Lactation
The safety of Domperidone + Lansoprazole during pregnancy and lactation is not well established. It's advised to consult your doctor before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.
Caution in Other Conditions
Patients with liver disease or heart conditions should exercise caution while taking Domperidone + Lansoprazole. Regular monitoring by a doctor may be necessary in such cases.
This medication should be used with caution in patients with underlying electrolyte imbalances as it can cause changes in potassium and magnesium levels in the blood.
Special Dietary and Lifestyle Recommendations
Regularly drinking water throughout the day can aid digestion and alleviate some gastrointestinal symptoms associated with this medication.
Incorporating regular physical activity into your daily routine could potentially help improve gastrointestinal motility.
Frequently asked questions
Does Domperidone + Lansoprazole cause drowsiness?
Domperidone + Lansoprazole may cause drowsiness in some individuals. If you experience this side effect, you should avoid activities that require mental alertness such as driving or operating machinery.
Can I stop taking Domperidone + Lansoprazole suddenly?
One should not stop taking Domperidone + Lansoprazole without consulting their doctor. Abruptly stopping the medication can lead to adverse effects, such as a resurgence of symptoms.
Can Domperidone + Lansoprazole cause weight gain?
Domperidone + Lansoprazole is not typically associated with significant weight gain. Domperidone is used to relieve nausea and improve gastric motility, while Lansoprazole is a proton pump inhibitor that reduces stomach acid. If you have concerns about weight gain, consult your doctor.
Is Domperidone + Lansoprazole available over the counter, or do I need a prescription?
Domperidone + Lansoprazole usually requires a prescription and is not available over the counter.
Is Domperidone + Lansoprazole a steroid?
No, Domperidone + Lansoprazole is not a steroid. This combination belongs to the group of gastroprokinetic and antiulcer agents, used primarily for managing conditions like gastroesophageal reflux disease and peptic ulcers.
How long does Domperidone + Lansoprazole take to work?
Domperidone + Lansoprazole can start providing symptom relief within a few days, but it may take several weeks for conditions like GERD and ulcers to fully heal.
Can I take Domperidone + Lansoprazole daily?
Domperidone + Lansoprazole can be taken daily as per your doctor's recommendation, often 30 minutes before meals.
Domperidone + Lansoprazole in other salts
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