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Dosulepin

Uses of Dosulepin

  • The primary use of Dosulepin is for the management of major depressive disorder (MDD). This medicine falls under the category of tricyclic antidepressants.

  • In addition to managing depression, Dosulepin may also be prescribed off-label for other conditions like neuropathic pain, fibromyalgia, migraine prevention, and insomnia.

Side effects of Dosulepin

  • Drowsiness

  • Dizziness

  • Increased appetite

  • Dry mouth

  • Constipation

How Dosulepin works

  • Dosulepin is a Tricyclic Antidepressant.

  • It works by increasing the levels of certain neurotransmitters, such as serotonin and norepinephrine, in the brain to help improve mood and relieve symptoms of depression.

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Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Dosulepin is available for use via the oral route in the form of tablets and capsules, providing a way for the medicine to be taken through the mouth.

Age and Dose Restrictions

  • This medicine is meant for use by adults. It is generally not prescribed for children due to a lack of established safety and efficacy data for paediatric populations.

Contraindications

  • Dosulepin is contraindicated in patients with known hypersensitivity to this medicine.

  • It should not be used by individuals who have recently had a myocardial infarction.

  • It is contraindicated in patients with arrhythmias, seizure disorders, bipolar disorder, urinary retention, or untreated narrow-angle glaucoma.

  • Patients with severe liver or kidney impairment should not use Dosulepin.

Other Medications to Avoid

  • This medicine may interact with monoamine oxidase inhibitors (such as phenelzine and tranylcypromine), other antidepressants (like sertraline, and fluoxetine), anticholinergic medicines (such as atropine, and scopolamine), antipsychotics (like risperidone), opioids (such as morphine, fentanyl), sedatives (like diazepam, lorazepam), and medicines like cimetidine and sympathomimetics (such as epinephrine).

Overdose and Missed Dose

  • An overdose of Dosulepin may lead to severe health issues including extreme drowsiness, loss of consciousness, seizures, abnormal heart rhythms, respiratory depression, hypotension, or hypothermia. Immediate medical attention is required.

  • If you miss a dose of Dosulepin, take it as soon as you remember unless it is close to the time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing drowsiness or dizziness, try taking Dosulepin at a time when these would be least disruptive, such as closer to bedtime.

  • For dry mouth or constipation, increase your intake of water throughout the day.

Use in Driving and Operating Machinery

  • Dosulepin may affect your ability to drive or operate heavy machinery. If you experience side effects such as drowsiness or blurred vision, it is advised that you avoid these activities.

Use in Pregnancy and Lactation

  • Dosulepin is not recommended during pregnancy or while breastfeeding. The benefits must clearly outweigh the risks before this medicine is used in these situations. Consult your doctor for advice on taking Dosulepin during these periods.

Caution in Other Conditions

  • Individuals with heart problems or those who have a history of seizures should use this medicine with caution.

  • Caution is advised for patients with liver or kidney conditions when using Dosulepin due to potentially altered metabolism and excretion rates which could increase side effects.

Special Dietary and Lifestyle Recommendations

  • Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins to support overall health while managing depression.

  • Regular physical activity can help improve mood and energy levels which is beneficial for individuals managing depression.

  • Ensure consistent sleep patterns by going to bed and waking up at the same time each day; adequate sleep supports mental health.

  • Avoid caffeine and high sugar foods which can lead to mood swings and exacerbate anxiety symptoms.

  • Practice relaxation techniques such as yoga or meditation to help manage stress and symptoms of anxiety disorders.

Frequently asked questions

No, Dosulepin is not a steroid. It is an antidepressant medication belonging to the tricyclic antidepressant (TCA) class, primarily used for managing major depressive disorder and anxiety disorders.

Yes, Dosulepin can have an effect on sleep due to its sedating properties. It can sometimes be prescribed in lower doses for managing insomnia.

There is no known impact of Dosulepin on fertility. However, it is recommended that you consult your doctor for personalised advice based on your health condition and history.

There are no known dietary restrictions while taking Dosulepin. However, maintaining a balanced diet is generally recommended while undergoing any kind of medical treatment.

Dosulepin is safe to take daily as long as it is taken according to the prescribed dosage and duration given by your doctor.

Dosulepin may take several weeks of consistent use to reach its full therapeutic effect. While improvements in sleep and appetite might be noticed within 1-2 weeks, significant mood improvement usually takes 4-6 weeks or longer.

The best time to take Dosulepin depends on the specific prescription given by your doctor. The research data provided suggests that the medicine is usually divided into smaller doses taken 2-3 times throughout the day.

Terms & Conditions


Dosulepin in other salts

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