Dutasteride + Silodosin
URINARY BLADDER RELAXANTUses of Dutasteride + Silodosin
- Dutasteride + Silodosin is used in the treatment of benign prostatic hyperplasia (BPH) (enlarged prostate) in men, a condition characterised by a noncancerous enlargement of the prostate gland due to excessive dihydrotestosterone hormone production.
- It also improves urine flow and reduces the feeling of incomplete bladder emptying.
- Additionally, it can slow the progression of BPH and reduce the need for surgical intervention.
Side effects of Dutasteride + Silodosin
- Nausea
- Low sexual desire
- Impotence
- Allergic reaction
- Decreased sperm count
- Abdominal Pain
How Dutasteride + Silodosin works
- Dutasteride is in a class of medications called 5-alpha reductase inhibitors. It blocks the conversion of testosterone into dihydrotestosterone (DHT), a hormone that causes the prostate gland to grow. This conversion is done by the enzyme 5-alpha-reductase, which has two types: type 1 and type 2. Type 2 is mainly active in the prostate, while type 1 works in the skin and liver. By inhibiting both types, dutasteride lowers DHT levels, helping to manage benign prostatic hyperplasia (BPH).
- Silodosin is an alpha-blocker. It targets specific alpha-1 receptors in the prostate, bladder, and surrounding areas. By blocking these receptors, it relaxes the smooth muscles in these tissues. This relaxation improves urine flow and helps reduce symptoms of benign prostatic hyperplasia (BPH).
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Dutasteride + Silodosin is available for use via the oral route (capsules and tablet).
Age and Dose Restrictions
- This combination is meant for adults and children above 18 years of age.
Contraindications
- Dutasteride + Silodosin is contraindicated in patients with known allergies to dutasteride or silodosin or who have severe liver or kidney disease.
Other Medications To Avoid With This Medicine
- It is advised against using any medications for hypertension (such as prazosin, terazosin), erectile dysfunction (sildenafil, tadalafil), fungal infections (itraconazole, ketoconazole), and HIV protease inhibitors (lopinavir, ritonavir) in conjunction with this combination. Before utilising any prescription or over-the-counter medications, consultation with your doctor is essential.
Overdose and Missed Dose
- Overdose of this combination can cause postural hypotension. Inform your doctor regarding these effects and follow the advice accordingly.
- If you forget to take this combination, take it as soon as you remember, but avoid repeating the dose.
Use In Driving And Operating Machinery
- This combination may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking this combination.
Use in Pregnancy and Lactation
- Pregnant or breastfeeding women should not take this combination.
Special Dietary & Lifestyle Recommendation
- Avoid alcohol when you are taking this combination.
Frequently asked questions
1. How much time does Dutasteride + Silodosin take to work?
This combination starts showing its effect within a few hours after consumption.
2. What warnings and precautions should I take while taking Dutasteride + Silodosin?
Avoid taking this combination if you experience an allergic reaction (hypersensitivity) to any of its components. Additionally, refrain from consuming alcohol while using this combination, as it may lead to a potential interaction, raising the risk of serious adverse effects. It is strongly advised to seek prompt medical consultation from a doctor.
3. Can I stop taking Dutasteride + Silodosin if I feel healthy?
Do not stop taking this combination without consulting your doctor, even if you feel healthy.
4. Is it safe for patients with kidney or liver issues?
Consult your doctor before taking this combination if you have kidney or liver issues to ensure its safety and proper dosage.
Dutasteride + Silodosin in other salts
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