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Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate

Uses of Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate

Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate is primarily used to manage HIV-1 infection in adults and children who weigh at least 40kg. It is part of the antiretroviral therapy (ART) class of medicines.

Side effects of Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate

  • Headache

  • Dizziness

  • Diarrhoea

  • Nausea

  • Fatigue

How Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate works

  • Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate is an antiretroviral combination.

  • Efavirenz (EFV) is a component that directly clings to a certain enzyme involved in the replication of the HIV virus and blocks its action, thereby disrupting the multiplication of the virus within the body.

  • Lamivudine (3TC) is another component that transforms into an active form inside your cells, and this active form interferes with the copying process of the HIV virus. It does so by incorporating itself into the viral DNA, leading to a premature halt in its replication.

  • Tenofovir Disoproxil Fumarate (TDF) is also a component that transforms into an active form inside your body's cells. This active form competes with a natural substance that the HIV virus needs to replicate, causing a stop in the production of viral DNA.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate is available for use via the oral route in the form of tablets. The combined medication provides a simplified dosing regimen that may assist in improving treatment adherence.

Age and Dose Restrictions

  • This medication is meant for adults and paediatric patients who weigh at least 40 kg.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to any of the active ingredients: Efavirenz, Lamivudine, or Tenofovir Disoproxil Fumarate.

Other Medications to Avoid

  • Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate can interact with antibiotics (such as rifampin), macrolide antibiotics (like clarithromycin), sedatives (such as midazolam), hormonal contraceptives (including the pill), opioids (like methadone), cholesterol-lowering medications (statins), and herbal supplements (such as St. John's Wort).

  • It's crucial to consult a doctor before starting any other prescription or over-the-counter medications.

Overdose and Missed Dose

  • If you accidentally take too much of this medicine, you may experience symptoms such as dizziness, sleepiness, or mental confusion. If you observe these symptoms, consult your doctor immediately.

  • If you forget to take a dose of this medicine, take it as soon as you remember, unless it is close to the time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage dizziness or lightheadedness, avoid sudden changes in posture, such as standing up quickly from a sitting or lying position.

  • If you experience diarrhoea, drink plenty of water to replace lost fluids.

Use in Driving and Operating Machinery

  • This medication may affect your ability to drive or operate heavy machinery. Avoid such activities if you feel dizzy or sleepy after taking this medication.

Use in Pregnancy and Lactation

  • The use of Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate during pregnancy (especially the first trimester) and lactation should be avoided unless specifically recommended by a doctor.

Caution in Other Conditions

  • Patients with hepatic (liver) impairment or renal (kidney) dysfunction should exercise caution when taking Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate.

  • Also, those with a history of mental illness, or seizures should consult their doctor before starting this medicine.

Special Dietary and Lifestyle Recommendations

  • Regular check-ups and blood tests to monitor your viral load and immune function are crucial.

  • Follow safe practices to prevent HIV transmission to others.

  • Maintain a healthy, balanced diet to support your immune system.

  • Regular physical activity can help maintain overall health.

  • Rest and reduce stress as much as possible.

Frequently asked questions

No, Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate is not a cure for HIV. It is an antiretroviral medication that helps manage HIV-1 infection by reducing the amount of the virus in your body and allowing your immune system to work better.

Yes, one of the possible side effects of Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate is mood changes. It may cause symptoms such as depression or abnormal dreams. If you experience any mood changes or other mental health problems while taking this medication, please report it to your doctor.

It is generally recommended to take Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate on an empty stomach, preferably at bedtime. However, always follow your doctor's advice on how and when to take your medication.

It is usually recommended to take this combination as per your doctor’s instructions regarding the timing.

While the combination works to reduce HIV levels quickly, it may take several weeks to months of consistent use for viral load reductions to be fully evident. Regular monitoring by your doctor is essential.

No, it is important to continue taking your antiretroviral therapy as prescribed by your doctor, even if your HIV levels are under control. Stopping your medication can lead to the virus becoming resistant to treatment, making it harder to manage in the future.

Yes, this combination is often used as part of a long-term treatment plan for managing HIV. Regular follow-ups with your doctor are necessary to monitor effectiveness and manage any potential side effects.

Terms & Conditions


Available medicines for EFAVIRENZ + LAMIVUDINE + TENOFOVIR DISOPROXIL FUMARATE
Dinmek 300/300/600 MG Tablet 30
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Telura Tablet 30
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Tenolam E Tablet 30
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Vonaday Tablet 30
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Avonza Tablet 30
Avonza Tablet 30
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T Lamirenz Tablet 30
T Lamirenz Tablet 30
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₹2337.00
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Trioday Tablet 30
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₹2833.17
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