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Enalapril + Hydrochlorothiazide

Uses of Enalapril + Hydrochlorothiazide

  • Enalapril + Hydrochlorothiazide is primarily used for the management of high blood pressure (hypertension). It belongs to the group of medications combining angiotensin-converting enzyme inhibitors with thiazide diuretics.

Side effects of Enalapril + Hydrochlorothiazide

  • Dizziness

  • Headache

  • Fatigue

  • Cough

  • Nausea

How Enalapril + Hydrochlorothiazide works

  • Enalapril + Hydrochlorothiazide is a combination of an ACE inhibitor and a diuretic used to manage high blood pressure.

  • Enalapril is a ACE inhibitor, blocks a particular enzyme in the body known as the angiotensin-converting enzyme. This prevents the body from producing a substance called angiotensin II which typically narrows blood vessels. When angiotensin II is blocked, blood vessels can relax and widen, allowing blood to flow more easily.

  • Hydrochlorothiazide, a thiazide diuretic, works by aiding the kidneys in removing extra water and salt from the body through urination. This helps in reducing the amount of fluid flowing through the blood vessels. The combined effect of these two components results in lowered blood pressure and reduced strain on the heart.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage forms available

  • Enalapril + Hydrochlorothiazide is available as an oral medication in the form of tablets.

Age and dose restrictions

  • This medicine is intended for use in adults and children above the age of 18 years.

Contraindications

  • This combination is contraindicated in patients with known allergies to enalapril or hydrochlorothiazide.

  • It is also contraindicated in individuals who have experienced angioedema (swelling under the skin) due to previous treatment with ACE inhibitors.

Other medications to avoid

  • Enalapril + Hydrochlorothiazide can interact with diuretics (such as furosemide and spironolactone), potassium supplements (like potassium chloride), mood stabilisers (such as lithium), nonsteroidal anti-inflammatory medicines (like ibuprofen and naproxen), insulin or diabetes medications (such as metformin), steroids (like prednisone) and narcotics (like codeine).

Overdose and missed dose

  • An overdose of Enalapril + Hydrochlorothiazide can cause severe dizziness, fainting, or kidney failure. If an overdose is suspected, seek immediate medical attention.

  • If you miss a dose of this medicine, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not double up on doses.

Management of side effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage side effects such as dizziness and headache.

  • Eating small, frequent meals can help manage nausea and diarrhoea.

  • Rest and avoid strenuous activities if you feel fatigued.

Use in driving and operating machinery

  • This medication may cause dizziness or fatigue. If you experience these side effects, refrain from driving or operating machinery until you are sure you can perform these activities safely.

Use in pregnancy and lactation

  • Enalapril + Hydrochlorothiazide is not recommended during pregnancy or while breastfeeding. It is advised to consult your doctor for advice before using this medicine if you are pregnant or planning a pregnancy, or if you are breastfeeding.

Caution in other conditions

  • Patients with kidney or liver disease should exercise caution when taking Enalapril + Hydrochlorothiazide. Regular monitoring of kidney and liver function may be required.

  • Patients with electrolyte imbalances should also exercise caution, as this combination can affect potassium levels in the blood.

Special dietary and lifestyle recommendations

  • Maintain a low-sodium diet as high sodium levels can increase blood pressure and counteract the benefits of the medication.

  • Regular physical activity can help in managing high blood pressure.

  • Reduce stress as much as possible as stress can raise your blood pressure.

Frequently asked questions

No, Enalapril + Hydrochlorothiazide is not steroids. Enalapril is an ACE inhibitor used to lower blood pressure and Hydrochlorothiazide is a diuretic that helps remove excess fluid from the body.

Enalapril + Hydrochlorothiazide is not directly associated with affecting sleep. However, if you experience any unusual symptoms such as sleep disorders, consult your doctor.

Enalapril + Hydrochlorothiazide is not associated with affecting fertility in men or women. However, if you have concerns about this, please discuss it with your doctor.

Enalapril + Hydrochlorothiazide is usually taken as advised by your doctor.

Most people begin to see a decrease in their blood pressure within a few hours after taking the first dose of Enalapril + Hydrochlorothiazide.

This medicine should be taken as advised by your doctor. The tablets should be swallowed whole with a glass of water.

While lifestyle changes such as regular exercise and a healthy diet can help manage high blood pressure, they should not replace the medication prescribed by your doctor.

Terms & Conditions


Available medicines for ENALAPRIL + HYDROCHLOROTHIAZIDE
Envas H Tablet 10
Envas H Tablet 10
Cadila Pharmaceuticals Ltd
Pack of 10 Units
₹85.28
MRP ₹104.00
18.00% OFF
Enalros H 5/12.5 MG Tablet 10
Enalros H 5/12.5 MG Tablet 10
Roussel Laboratories Pvt Ltd
Pack of 10 Units
₹42.41
MRP ₹85.00
50.10% OFF
Tenam Ht 10/25mg Tablet 20
Tenam Ht 10/25mg Tablet 20
Caplet India Private Limited
Pack of 20 Units
₹74.19
MRP ₹90.48
18.00% OFF
Enapril Ht Tablet 15
Enapril Ht Tablet 15
Intas Pharmaceuticals Ltd
Pack of 15 Units
₹140.22
MRP ₹171.00
18.00% OFF
Enzide 10/25 MG Tablet 10
Enzide 10/25 MG Tablet 10
Cadila Pharmaceuticals Ltd
Pack of 10 Units
₹26.24
MRP ₹32.00
18.00% OFF
Enace D 5 Tablet 30
Enace D 5 Tablet 30
Abbott Healthcare Pvt. Ltd
Pack of 30 Units
₹198.09
MRP ₹241.57
18.00% OFF
Enace D 10 Tablet 30
Enace D 10 Tablet 30
Abbott Healthcare Pvt. Ltd
Pack of 30 Units
₹328.78
MRP ₹400.95
18.00% OFF
Tenam Ht 10/25mg Tablet 10
Tenam Ht 10/25mg Tablet 10
Caplet India Private Limited
Pack of 10 Units
₹74.19
MRP ₹90.48
18.00% OFF

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