Enzalutamide

Dosage Forms Available

• Enzalutamide can be taken orally (capsules).

Age and Dose Restrictions

• This medicine is meant for adult men only.

Contraindications

• Enzalutamide is contraindicated in patients who have known hypersensitivity to Enzalutamide or any of the ingredients in the capsules.

Other Medications to Avoid

• Enzalutamide may interact with antibiotics (such as rifampin and clarithromycin), seizure medicines (like carbamazepine and phenytoin), and antifungal medicines (including itraconazole and ketoconazole).

Overdose and Missed Dose

• An overdose of Enzalutamide may cause severe side effects, such as seizures and a brain disorder known as posterior reversible encephalopathy syndrome (PRES). Obtain immediate medical help if you suspect an overdose.

• If you miss a dose of Enzalutamide, take it as soon as you remember. But if it is nearly time for your next dose, skip the missed one. Do not take a double dose to compensate for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of fluids may help manage constipation.

• Resting or doing light physical activity can help manage fatigue.

• If the medicine causes dizziness, avoid fast movements and stand up slowly from a sitting or lying position.

Use in Driving and Operating Machinery

• Enzalutamide may affect your ability to drive or operate heavy machinery, as this medication can cause fatigue, dizziness, and seizures.

Use in Pregnancy and Lactation

• Enzalutamide is not indicated for females; it may cause harm during pregnancy and has been found to pass into animal milk.

Caution in Other Conditions

• Patients with a history of seizures, brain injury, stroke, or brain tumours should exercise caution when taking this medicine.

• Patients with heart disease, diabetes, high blood pressure, high cholesterol, or osteoporosis should also consult their doctor before starting this medicine.

Special Dietary and Lifestyle Recommendations

• Drinking plenty of fluids can help minimise the risk of constipation associated with Enzalutamide.

• Limiting salt intake can help control high blood pressure caused by this medicine.

• Regular monitoring of blood glucose levels is advised for those with diabetes.

• Regular heart check-ups are advised for those with heart conditions.