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Esomeprazole

ANTACID

Uses of Esomeprazole

  • Esomeprazole is primarily used to manage gastro-oesophageal reflux diseases (GERD). 
  • It is also used to reduce the risk of occurrence of NSAID associated gastric ulcers, H.Pylori associated duodenal ulcers, and Zollinger-Ellison syndrome.
  • It Heals inflammation and damage to the esophagus caused by acid reflux.
  • It  protects the stomach lining from damage caused by long-term use of NSAIDs.

Side effects of Esomeprazole

  • Flatulence
  • Constipation
  • Diarrhoea
  • Nausea
  • Headache
  • Dry mouth 
  • Drowsiness
  • Abdominal pain

How Esomeprazole works

  • Esomeprazole is a proton pump inhibitor (PPI), which means it works by inhibiting the proton pumps in the stomach lining.
  • By inhibiting the proton pumps, esomeprazole significantly reduces the production of gastric acid. This reduction in acid helps to decrease the acidity of the stomach contents.
  • Lowering stomach acid levels allows for the healing of acid-related damage to the esophagus, stomach, and duodenum. It also helps to alleviate symptoms such as heartburn, acid reflux, and indigestion.
  • With less acid being secreted, the pH level in the stomach rises (becomes less acidic). This higher pH environment reduces the potential for acid damage to the gastrointestinal tract and helps in managing conditions like GERD, erosive esophagitis, and peptic ulcers.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Esomeprazole is available for use via oral route (tablet, capsules, granules for suspension).

Age and Dose Restrictions

  • It can be used by adults and children above 12 years of age as per appropriate dose calculations.

Overdose and Missed Dose

  • If you miss a dose of Esomeprazole, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.
  • Long term use of Esomeprazole carries the risk of Vitamin B12 deficiency,hypomagnesemia, risk of Hip fractures.

Use In Driving And Operating Machinery

  • It is prudent to avoid driving or operating heavy machinery while on Esomeprazole, as it has been reported to cause drowsiness.

Use in Pregnancy and Lactation

  • Esomeprazole should be used with caution in Pregnant females, while its use is not recommended in Lactating females.

Special Dietary & Lifestyle Recommendation

  • It's essential to maintain a healthy weight by following a balanced diet. Avoid consuming foods that can exacerbate your symptoms, such as spicy and fat rich food. 
  • Reducing your intake of caffeinated drinks like tea, coffee, and cola, avoiding alcohol and quitting smoking help in enhancing the benefit obtained by the use of Esomeprazole.
  • Elevating your head and shoulders while sleeping can prevent stomach acid from refluxing during the night, providing relief.

Frequently asked questions

Esomeprazole reduces the production of acid in the stomach.

You may start feeling better within a few hours of taking it, but it may take several weeks to see significant improvement for some conditions.

Long-term use of Esomeprazole may be associated with some side effects such as Vitamin B12 deficiency, increased risk of Hip fractures, Hypomagnesemia, etc.

 Esomeprazole should only be stopped after completion of a prescribed course or after consultation with a doctor.

Esomeprazole is an effective medicine for indigestion. Your doctor will decide if other medications are needed for your condition. 

It's better to avoid taking Esomeprazole with antacids as they may interfere with its absorption. Consult your doctor regarding their simultaneous use.

Esomeprazole is not known to affect contraception methods like birth control pills.

Before you begin taking esomeprazole, it's crucial to inform your healthcare provider if you are currently using medications like digoxin, cilostazol, itraconazole, ketoconazole, posaconazole or voriconazole, methotrexate, phenytoin, rifampicin, clopidogrel or warfarin and HIV medicines.

No. Alcohol consumption should be avoided while taking Esomeprazole.

The best time to take Esomeprazole is at least one hour before meals, preferably in the morning or as your doctor directs. This allows the medication to effectively reduce stomach acid production and maximize its therapeutic benefits.

Yes, you can take antacids along with Esomeprazole if you need additional relief from heartburn or indigestion. However, it's best to take them at different times to avoid potential interactions. It always good to discuss such situations with your doctor.

Yes, Esomeprazole can be taken with domperidone. This combination is often used to manage symptoms of gastroesophageal reflux disease (GERD) and other gastrointestinal disorders, as they work together to reduce acid and improve motility.

Esomeprazole is not commonly associated with weight gain. However, some individuals might experience changes in appetite or weight as a side effect, although this is relatively rare.

It's generally not recommended to take Esomeprazole with ranitidine as both medications reduce stomach acid, and using them together may not provide additional benefit and could increase the risk of side effects. Consult your healthcare provider for appropriate treatment options.

Terms & Conditions


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