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Etodolac + Tolperisone

Uses of Etodolac + Tolperisone

  • Etodolac + Tolperisone is primarily used in the management of acute musculoskeletal pain conditions and muscle spasms and belongs to the group of NSAIDs and muscle relaxants.

  • It is also indicated for conditions that involve pain and inflammation along with muscle spasms, such as osteoarthritis with muscle spasms.

Side effects of Etodolac + Tolperisone

  • Dyspepsia

  • Abdominal pain

  • Nausea

  • Diarrhoea

  • Dizziness

How Etodolac + Tolperisone works

  • Etodolac + Tolperisone is a combination of a nonsteroidal anti-inflammatory medicine and a muscle relaxant.

  • Etodolac is a nonsteroidal anti-inflammatory medicine (NSAID). It works by blocking an enzyme called cyclooxygenase which makes prostaglandins. Prostaglandins are substances that the body produces in response to injury and cause pain, swelling, and fever. By reducing the production of prostaglandins, Etodolac relieves these symptoms.

  • Tolperisone is a muscle relaxant. It is thought to work primarily by acting in the spinal cord and brain stem to reduce muscle spasms. This helps to relieve pain and improve mobility in conditions where muscle spasm is an issue.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Etodolac + Tolperisone is available for use as oral tablets.

  • This combination medicine is taken by mouth.

Age and Dose Restrictions

  • This medicine is meant for adult use.

Contraindications

  • Etodolac + Tolperisone is contraindicated in patients known to have hypersensitivity to etodolac, tolperisone, or other NSAIDs.

  • It is also contraindicated in individuals with a history of asthma, urticaria, or allergic reactions following aspirin or other NSAID use.

  • Not suitable for use in the treatment of perioperative pain from coronary artery bypass graft surgery.

  • Contraindicated in patients with active gastrointestinal bleeding or peptic ulcer disease.

Other Medications to Avoid

  • This combination may interact with anticoagulants (like warfarin), muscle relaxants (such as baclofen), NSAIDs (like ibuprofen), anticholinergic agents (such as atropine), and antihypertensives (like atenolol). These interactions could increase the risk of gastrointestinal side effects, including irritation or ulcers, and amplify the muscle relaxant effects, potentially causing excessive drowsiness, weakness, or reduced blood pressure.

Overdose and Missed Dose

  • An overdose of Etodolac + Tolperisone may result in severe gastrointestinal problems, significant dizziness, severe headaches, or an increase in blood pressure. Immediate medical attention is advised if an overdose is suspected.

  • If you miss a dose of this medicine, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose; do not double the dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For nausea, try taking this medicine with food or a glass of milk.

  • If experiencing dizziness, ensure to move slowly from lying down or sitting to a standing position.

  • Drinking adequate water can help manage mild dehydration symptoms if experiencing diarrhoea.

Use in Driving and Operating Machinery

  • This medication can cause dizziness and somnolence. You should avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

  • The safety of Etodolac + Tolperisone during pregnancy and lactation has not been fully established. Therefore, it should only be used when clearly needed and directed by a doctor.

Caution in Other Conditions

  • Caution is advised in patients with cardiovascular disease or risk factors for cardiovascular events.

  • People with kidney or liver impairment should use this medicine cautiously and under strict medical supervision due to potential alterations in medicine metabolism and excretion.

Special Dietary and Lifestyle Recommendations

For individuals managing acute musculoskeletal conditions:

  • Maintain a balanced diet rich in calcium and vitamin D to support bone health.

  • Incorporate anti-inflammatory foods like turmeric, ginger, and omega-3 fatty acids which may help reduce inflammation naturally.

  • Regular gentle exercise such as walking or swimming can help maintain joint function and reduce stiffness.

  • Adequate rest is crucial during acute pain episodes; however, prolonged immobility should be avoided as it may worsen muscle stiffness.

  • Weight management can be crucial in reducing stress on weight-bearing joints thus improving symptoms.

Frequently asked questions

No, Etodolac + Tolperisone is not a steroid. It is a combination of an NSAID and a muscle relaxant.

There might be some cases where Etodolac + Tolperisone could lead to drowsiness or somnolence, but these are not very common. If you experience excessive drowsiness or changes in your sleep patterns after consuming this medicine, consult your doctor.

There is no evidence to suggest that the use of Etodolac + Tolperisone affects fertility in men or women. However, if you are planning a pregnancy or have concerns about fertility, you should discuss this with your doctor.

There are no specific diet restrictions while taking Etodolac + Tolperisone. However, it is advisable to maintain a healthy diet as poor nutrition can delay recovery from painful musculoskeletal conditions.

It should be taken as per the doctor's advice. The medication should be used at the lowest effective dose for the shortest duration consistent with treatment goals.

After oral dosing, both etodolac and tolperisone are rapidly absorbed from the gastrointestinal tract. Peak plasma levels occur within 1-2 hours.

Etodolac + Tolperisone can be taken at any time of the day, but it is often recommended to take it with meals. The exact timing would depend on your doctor's advice.

Terms & Conditions


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