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Ezetimibe + Pitavastatin

Uses of Ezetimibe + Pitavastatin

  • The main use of Ezetimibe + Pitavastatin is to manage high levels of cholesterol in the blood. This medication belongs to the group of lipid-regulating medicines.

  • Additionally, it is used to manage conditions such as primary hyperlipidemia or mixed dyslipidemia and to lower cholesterol in patients with homozygous familial hypercholesterolemia. It is also used to reduce high blood levels of plant-based sterols in people with homozygous sitosterolemia.

Side effects of Ezetimibe + Pitavastatin

  • Headache

  • Diarrhoea

  • Joint pain

  • Muscle pain and weakness

  • Pain in extremities

How Ezetimibe + Pitavastatin works

  • Ezetimibe + Pitavastatin is a combination medication designed to manage high cholesterol levels.

  • Ezetimibe works by reducing the absorption of cholesterol from your intestines. It achieves this by blocking a specific transport protein that transfers cholesterol from your intestines into your bloodstream.

  • Pitavastatin is part of the statin group of medicines. It functions by inhibiting an enzyme called HMG-CoA reductase, which plays a crucial role in producing cholesterol in your liver. This leads to a reduction in the synthesis of cholesterol within the liver itself.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ezetimibe + Pitavastatin is available for use as an oral tablet. This formulation allows for the medicine to be taken by mouth, facilitating ease of administration.

Age and Dose Restrictions

  • This medicine is intended for use in adults.

  • It is not typically prescribed for children or adolescents.

Contraindications

  • Ezetimibe + Pitavastatin is contraindicated in patients with active liver disease or unexplained persistent elevations in liver enzymes.

  • It is also contraindicated in patients who have shown hypersensitivity to any component of the formulation.

Other Medications to Avoid

  • This combination may interact with immunosuppressants (such as cyclosporine), antibiotics (like erythromycin), lipid-modifying agents (such as fibrates), and anticoagulants (like warfarin).

  • These interactions can increase the risk of side effects or reduce the effectiveness of Ezetimibe + Pitavastatin.

Overdose and Missed Dose

  • In the event of an overdose, no specific antidote is available. Supportive and symptomatic treatment should be initiated. Hemodialysis may not be beneficial due to the high plasma binding of both components.

  • If you miss a dose, take it as soon as you remember. If it is near the time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For mild digestive issues, consider taking your medication with food if not contraindicated.

  • Stay well-hydrated especially if experiencing diarrhoea, as it helps manage dehydration risks.

Use in Driving and Operating Machinery

  • This medication may impair your ability to drive or operate machinery. If you experience dizziness or muscle weakness after taking this medication, avoid engaging in such activities until these effects subside.

Use in Pregnancy and Lactation

  • Ezetimibe + Pitavastatin is contraindicated during pregnancy and breastfeeding. The potential risks associated with its use in these conditions have not been fully established.

  • If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medication.

Caution in Other Conditions

  • Patients with kidney or liver function impairment should use Ezetimibe + Pitavastatin with caution. Regular monitoring of liver enzymes and kidney function might be necessary.

  • Caution is advised for older adults and those of Asian descent due to increased sensitivity and risk of side effects.

Special Dietary and Lifestyle Recommendations

  • Maintain a low-cholesterol and low-fat diet to help manage cholesterol levels effectively while using Ezetimibe + Pitavastatin.

  • Regular physical activity such as 30 minutes of brisk walking most days can help improve cardiovascular health.

  • Limit alcohol consumption as it can exacerbate liver issues and reduce the effectiveness of lipid management strategies.

  • Ensure adequate hydration throughout the day, which supports overall health and helps mitigate some potential side effects like muscle cramps or constipation caused by the medication.

Frequently asked questions

No, Ezetimibe + Pitavastatin is not a steroid. It is a combination medicine used to manage high cholesterol levels in the blood.

Ezetimibe + Pitavastatin does not typically affect sleep patterns. However, individual responses can vary. If you notice any changes to your sleep, speak to your doctor.

There is no evidence suggesting that Ezetimibe + Pitavastatin affects fertility. If you are trying to conceive or have concerns about fertility, consult your doctor.

You should avoid grapefruit and grapefruit juice while taking this medication, as they can increase the risk of side effects.

Yes, it is generally safe to take Ezetimibe + Pitavastatin daily as prescribed by your doctor.

The time taken for Ezetimibe + Pitavastatin to start working can vary depending on individual health conditions and the severity of the disease. Your doctor will be able to give you a more precise timeline.

Ezetimibe + Pitavastatin usually requires a doctor's prescription and is not readily available over the counter.

Terms & Conditions


Available medicines for EZETIMIBE + PITAVASTATIN
Ezenon P4 Tablet 10
Ezenon P4 Tablet 10
Indinon Pharma
Pack of 10 Units
₹241.90
MRP ₹295.00
18.00% OFF
Ptvs Fb Tablet 10
Ptvs Fb Tablet 10
Druto Laboratories
Pack of 10 Units
₹210.25
MRP ₹256.40
18.00% OFF
Ptvs Plus Tablet 10
Ptvs Plus Tablet 10
Druto Laboratories
Pack of 10 Units
₹217.90
MRP ₹265.73
18.00% OFF
Livastat Ez Tablet 10
Livastat Ez Tablet 10
Novazen Pharmaceuticals
Pack of 10 Units
₹262.40
MRP ₹320.00
18.00% OFF

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