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Ezetimibe + Rosuvastatin

Uses of Ezetimibe + Rosuvastatin

  • The primary use of Ezetimibe + Rosuvastatin is to manage high cholesterol levels in the blood. This combination medicine belongs to the group of cholesterol absorption inhibitors and statins.

  • It is also used to manage conditions such as primary hypercholesterolemia, mixed dyslipidemia, homozygous familial hypercholesterolemia, and homozygous sitosterolemia. The medicine can be used alone or with other lipid-lowering treatments.

Side effects of Ezetimibe + Rosuvastatin

  • Headache

  • Abdominal pain

  • Fatigue

  • Nausea

  • Joint pain

How Ezetimibe + Rosuvastatin works

  • Ezetimibe + Rosuvastatin is a cholesterol-lowering combination.

  • Ezetimibe falls into the category of cholesterol absorption inhibitors. It reduces the absorption of dietary cholesterol in the intestines by blocking a specific transport protein. This leads to a decrease in the level of bad cholesterol in your blood.

  • Rosuvastatin, an HMG-CoA reductase inhibitor, is a statin. It works by reducing cholesterol production in the liver and increasing the number of LDL receptors on liver cells to enhance the uptake and catabolism of bad cholesterol.

  • Together, these medicines work in synergy to manage high cholesterol levels by both reducing the absorption and production of cholesterol.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ezetimibe + Rosuvastatin is available for oral administration via tablets.

Age and Dose Restrictions

  • This medicine is primarily meant for adults.

  • However, it can also be given to children above the age of 10 years only under a doctor's supervision.

Contraindications

  • Ezetimibe + Rosuvastatin is contraindicated in patients with known hypersensitivity to Ezetimibe, Rosuvastatin, or any other components of the formulation.

  • It is also contraindicated in patients with active liver disease or unexplained persistent elevations in liver enzyme levels.

Other Medications to Avoid

  • This combination may interact with immunosuppresants (like cyclosporine), fibric acid derivatives (such as gemfibrozil and fenofibrate), niacin, coumarin anticoagulants (like warfarin), protease inhibitors used to treat HIV infection (like amprenavir and atazanavir) azole antifungals (such as itraconazole and ketoconazole), and macrolide antibiotics (like erythromycin and clarithromycin).

  • It is important to consult your doctor before starting any new medications while you are taking Ezetimibe + Rosuvastatin.

Overdose and Missed Dose

  • Overdosing on Ezetimibe + Rosuvastatin may lead to severe muscle problems and liver damage. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage headaches, try to rest and keep yourself well-hydrated.

  • If you have diarrhoea, drink plenty of fluids to avoid dehydration.

  • Simple painkillers can help with joint pain.

Use in Driving and Operating Machinery

  • Ezetimibe + Rosuvastatin may cause dizziness or sleepiness in some people. If you experience these side effects, avoid driving or operating heavy machinery until you feel better.

Use in Pregnancy and Lactation

  • Ezetimibe + Rosuvastatin is not recommended during pregnancy or breastfeeding unless advised by your doctor.

  • Always consult with your doctor before taking any medication during pregnancy or breastfeeding.

Caution in Other Conditions

  • Patients with a history of liver disease should use Ezetimibe + Rosuvastatin with caution.

  • Also, patients at an increased risk of muscle problems (myopathy/rhabdomyolysis) should be cautious while using this medicine.

Special Dietary and Lifestyle Recommendations

  • Maintain a healthy diet low in saturated fats and cholesterol.

  • Engage in regular physical activity as recommended by your doctor.

  • Limit alcohol consumption as it can increase your triglyceride levels and possibly damage your liver.

  • Regularly monitor your cholesterol levels as directed by your doctor.

Frequently asked questions

No, Ezetimibe + Rosuvastatin is not a steroid. It is a combination medicine used to manage high cholesterol levels in the blood.

Ezetimibe + Rosuvastatin does not typically affect sleep. However, individual reactions can vary. If you experience sleep disturbances, consult your doctor

There is no evidence to suggest that Ezetimibe + Rosuvastatin negatively impacts fertility. However, if you have concerns about fertility, speak with your doctor.

No, never stop your medication without talking to your doctor.

Yes, Ezetimibe + Rosuvastatin is usually taken as directed by your doctor.

Significant reductions in cholesterol levels may be seen within two weeks of starting treatment. However, it may take four weeks or more to see the maximal effect.

Ezetimibe + Rosuvastatin can be taken at any time of the day, with or without food.

Terms & Conditions


Available medicines for EZETIMIBE + ROSUVASTATIN
Crevast Ez 20 Tablet 10
Crevast Ez 20 Tablet 10
Eris Lifesciences Ltd
Pack of 10 Units
₹160.56
MRP ₹195.80
18.00% OFF
Razel Ez 20 Tablet 10
Razel Ez 20 Tablet 10
Glenmark Pharmaceuticals Ltd.
Pack of 10 Units
₹198.35
MRP ₹241.89
18.00% OFF
Roseday Ez Tablet 10
Roseday Ez Tablet 10
Usv Pvt Ltd
Pack of 10 Units
₹229.11
MRP ₹279.40
18.00% OFF
Rozavel Ez Tablet 10
Rozavel Ez Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹193.52
MRP ₹236.00
18.00% OFF
Rosuvas Ez 10 Tablet 10
Rosuvas Ez 10 Tablet 10
Emcure Pharmaceuticals Ltd
Pack of 10 Units
₹322.96
MRP ₹393.85
18.00% OFF
Roseday Ez 20 Tablet 10
Roseday Ez 20 Tablet 10
Usv Pvt Ltd
Pack of 10 Units
₹288.64
MRP ₹352.00
18.00% OFF
Rozucor Ez Tablet 10
Rozucor Ez Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹216.07
MRP ₹263.50
18.00% OFF
Razel Ez 10 Tablet 10
Razel Ez 10 Tablet 10
J B Chemicals And Pharmaceuticals Ltd
Pack of 10 Units
₹140.33
MRP ₹171.13
18.00% OFF

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