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Favipiravir

ANTIVIRAL

Uses of Favipiravir

  • Favipiravir has been used in the treatment of COVID-19, particularly in cases with mild to moderate symptoms.
  • Originally developed for influenza, favipiravir can be used to treat flu infections, especially those resistant to other antiviral medications.
  • Favipiravir has shown activity against a range of other viruses, including certain RNA viruses like Ebola and Lassa fever. 

Side effects of Favipiravir

The side effects of Favipiravir are:

  • Increased uric acid level in blood
  • Diarrhea
  • Decreased white blood cell count (neutrophils)
  • Increased liver enzymes
  • Increased triglyceride level in blood

How Favipiravir works

Favipiravir works as an antiviral medication primarily by inhibiting viral RNA polymerase, which is crucial for the replication of RNA virus. Here’s Favipiravir’s mechanism of action:

  • Favipiravir is classified as an antiviral medication.
  • It inhibits viral transcription and replication by binding to RNA-dependent RNA polymerase (RdRp).
  • By targeting RdRp, favipiravir prevents the replication of the SARS-CoV-2 virus, which is responsible for COVID-19.
  • This action reduces the viral load in the body, helps prevent the spread of infection, and can improve the healing process.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Doctors recommend Favipiravir to treat mild to moderate symptoms of covid-19. Consult your doctor if you suffer from gout, uric acid, liver, or kidney disease. This medication should be taken with precaution by elderly patients during their overall health must be maintained. If you have symptoms of an allergic reaction, like a red or blistering rash, difficulty swallowing or breathing, or swelling of the eyelids, lips, face, throat, or tongue, you should consult a doctor immediately. Favipiravir medication may be taken with or without food. However, it may help to prevent nausea and vomiting by taken with meals. It is recommended to use a birth control method while taking this medication and for seven days after the treatment stops. Do not use the remaining Favipiravir medication to treat any future symptoms. Before taking any antiviral medication, it is important to consult your doctor. You should notify your doctor if you are pregnant, planning to become pregnant, or already breastfeeding.

Dosage Forms Available

  • Favipiravir can be combined orally (tablet).

Age And Dose Restrictions

  • Favipiravir is intended for adults and is not recommended for children and adolescents under the age of 18.

Contraindications

  • Favipiravir is contraindicated in pregnant women due to the risk of fetal harm and should not be used by women who are breastfeeding. It is also contraindicated for patients with a known hypersensitivity to Favipiravir or any of its components.

Medications To Avoid With This Drug 

  • Avoid taking antiviral medicines (ribavirin), anticoagulants (warfarin), anticonvulsants (phenytoin), immunosuppressants and certain antibiotics (Pyrazinamide). It may interact with Favipiravir and reduce its effectiveness.

Frequently asked questions

No, it is not safe to take this medication during pregnancy because there is clear evidence that the drug causes a risk to the growing fetus. Consult your doctor before taking any medications because research on animals and pregnant women has shown serious harmful effects on the developing baby.

Within 24 hours, you must experience the benefit of Favipiravir.

No, it's likely unsafe to take this medication during breastfeeding. According to human data, the medicine may enter the breast milk and damage the unborn baby.

Yes, patients with kidney problems should take precautions while using Favipiravir. Some patients may need a dosage modification. If you have any problems, you should consult your doctor.

Yes, Diarrhoea is a risk after taking this medication. Therefore, drink lots of fluids and take probiotics to avoid excessive fluid loss (dehydration). Do not use anti-Diarrhoea medication on your own. If the disease worsens, consult your doctor.

Yes, patients with liver problems should take precautions while using Favipiravir. Some patients may need a dosage modification. If you have any problems, you should consult your doctor.

Do not use Favipiravir if you have an allergic reaction (hypersensitivity) to any of its components. We recommend that you consult a doctor as soon as possible.

No, please do not stop taking Favipiravir without first consulting your doctor. There is a chance that viral symptoms may return if this medication is suddenly stopped.

Yes, an allergic reaction may be caused by taking Favipiravir. You should consult a doctor if you have symptoms of an allergic response, such as red or blistering rash, difficulty swallowing or breathing, or swelling of the eyelids, lips, face, throat, or tongue.

It is not recommended to use any anti-TB agents (like pyrazinamide), hyperglycemic agents (like repaglinide), methylxanthines (like theophylline), anti-viral agents (like famciclovir, acyclovir), and nonsteroidal anti-inflammatory drugs (like sulindac). Before using any prescription or over-the-counter medications, you must consult with your doctor.

No, there is no evidence that this medication is addictive, but it is important to take the medication according to the directions. However, if you are not feeling well, you should make an appointment with your doctor.

No, avoid consuming alcohol while taking Favipiravir because it could increase dizziness and drowsiness.

No, this medication is unlikely to affect fertility in either men or women. However, there is currently insufficient evidence to justify any clear conclusion. Consult your doctor for the most accurate information.

Favipiravir is effective for treating COVID-19, especially in patients with mild-to-moderate illness. The best time to start treatment with Favipiravir is as soon as possible after the onset of COVID-19 symptoms, ideally within the first few days. It induces viral clearance within 7 days and contributes to clinical improvement within 14 days.

Favipiravir is usually taken for 5 to 14 days, starting with an initial higher dose followed by a maintenance dose, as prescribed by a doctor.

Patients with diabetes and hypertension can take Favipiravir, but they should do so under close medical supervision to manage potential interactions and side effects.

Terms & Conditions

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