Flupenthixol

Dosage Forms Available

• Flupenthixol can be taken orally (tablet and oral solution) and administered intramuscularly (long-acting injectable depot formulations).

Age and Dose Restrictions

• Flupenthixol is generally prescribed for adults and adolescents above the age of 12.

Contraindications

• Flupenthixol is contraindicated in patients with known hypersensitivity to thioxanthene antipsychotics. It should not be administered to those suffering from severe CNS depression, blood dyscrasias, or severe hepatic impairment.

Other Medications to Avoid

• Flupenthixol may interact with antihypertensives (e.g., beta-blockers such as atenolol or propanalol), diuretics (e.g., furosemide and toresimide), antiepileptics (e.g., carbamazepine and brivaracetam), and CYP2D6 inhibitors (e.g., fluoxetine, paroxetine).

Overdose and Missed Dose

• Overdose of Flupenthixol may lead to symptoms like nervous system depression or stimulation. If you've taken more than the prescribed dose and observe these symptoms, consult your doctor immediately.

• If you forget a dose of Flupenthixol, take it as soon as you remember it. However, do not double the dose to make up for a missed one.

Management of Side Effects

Most side effects of Flupenthixol are temporary and generally harmless and resolve once the medication is discontinued. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor immediately.

• Drinking plenty of water may help alleviate some common side effects like dry mouth and constipation.

• Resting and avoiding heavy physical activity may help cope with drowsiness or fatigue caused by the medication.

Use in Driving and Operating Machinery

• Flupenthixol may make you feel drowsy or dizzy, which could impair your ability to drive or operate heavy machinery. Refrain from such activities if you experience these side effects.

Use in Pregnancy and Lactation

• The safety of Flupenthixol during pregnancy and lactation is not well established. It should only be used if the doctor suggests that the benefits outweigh the risks.

Caution in Other Conditions

• Patients with pre-existing cardiovascular disease, seizure disorders, diabetes, glaucoma, or prostatic hypertrophy should exercise caution when taking Flupenthixol. Caution is advised for patients with pheochromocytoma. Regular monitoring and dose adjustments may be necessary in these cases.

Special Dietary and Lifestyle Recommendations

• Ensure a consistent sleep schedule for adequate rest.