Flurbiprofen is used for the relief of pain, tenderness, swelling, and stiffness associated with osteoarthritis and rheumatoid arthritis. It belongs to the propionic acid derivative class of non-steroidal anti-inflammatory drugs (NSAIDs).
Additionally, Flurbiprofen manages symptoms of ankylosing spondylitis, a type of arthritis that primarily affects the spine. Also, its ophthalmic solution is used to control eye inflammation before and after eye surgery or laser surgery in patients who cannot use steroids.
Stomach upset
Nausea or vomiting
Diarrhoea or constipation
Headache, dizziness, or drowsiness
Eye redness and itching (ophthalmic use)
Flurbiprofen is a non-steroidal anti-inflammatory drug (NSAID).
It works by inhibiting the action of cyclooxygenase (COX) enzymes in the body. These enzymes are responsible for the production of prostaglandins, which are chemical messengers that play a role in inflammation, pain, and fever. By blocking COX enzymes, Flurbiprofen reduces the production of prostaglandins, thereby relieving symptoms of pain and inflammation.
Doctor of Medicine
BMS, FMC, MD Resident
Flurbiprofen is available for use via oral route in the form of tablets. It is taken by mouth, swallowed with a liquid.
This medicine is also available as an ophthalmic solution, which is applied directly to the eye.
Flurbiprofen is intended for use in adults and children above 12 years of age.
The dosage and duration of treatment are determined by the patient's overall health condition, severity of symptoms, and response to treatment.
This medicine is contraindicated in patients with known hypersensitivity to Flurbiprofen or other NSAIDs.
It should not be used in patients with active gastrointestinal bleeding or ulceration, severe renal impairment or renal failure, and severe hepatic impairment or liver failure.
Flurbiprofen may interact with anticoagulants (e.g., apixaban and warfarin), antiplatelet agents (e.g., prasugrel and clopidogrel), other NSAIDs or aspirin, selective serotonin reuptake inhibitors (e.g., citalopram and dapoxetine), diuretics (e.g., spironolactone and torsemide), ACE inhibitors (e.g., moexipril and perindopril), and angiotensin II receptor blockers (azilsartan andcandesartan), antimanic drug (e.g., lithium and valproate), and antimetabolites (e.g., methotrexate and aminopterin).
In case of an overdose of Flurbiprofen, immediate medical attention is required as it can cause symptoms like severe stomach pain, vomiting, drowsiness, fainting, or even coma.
If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not double your dose to make up for the missed one.
Most side effects of Flurbiprofen are temporary and generally resolve when the medication is discontinued. However, if any severe side effects are experienced or if symptoms worsen, consult your doctor.
Drinking plenty of fluids can help manage side effects like dizziness and upset stomach.
In case of constipation, include more fibre in your diet from sources like fresh fruits, vegetables, and whole grains.
Flurbiprofen may cause drowsiness, dizziness or blurred vision. If you experience any of these effects, avoid driving or operating heavy machinery until you feel well again.
The use of Flurbiprofen is not recommended during pregnancy and while breastfeeding unless deemed necessary by your doctor. Always consult your doctor before using this medicine if you are pregnant or nursing.
Patients with a history of ulcers, gastrointestinal bleeding, liver or kidney disease, heart failure, hypertension, or asthma should exercise caution when taking Flurbiprofen. Always consult your doctor before starting this medication.
Maintain a balanced diet rich in fruits, vegetables, and whole grains to support overall health and well-being.
Regular physical activity can help manage symptoms of osteoarthritis and rheumatoid arthritis.
Avoid smoking and limit alcohol consumption, as these can worsen inflammation and pain.
Adequate rest and stress management techniques such as meditation or yoga can also be beneficial.
Frequently asked questions
No, Flurbiprofen is not a steroid. It is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the propionic acid derivative class.
Flurbiprofen does not typically affect sleep. However, individual reactions to medication may vary, and it is always recommended to monitor your body's responses to a new medicine.
Flurbiprofen should be taken as per your doctor's recommendation. Long-term use can increase the risk of gastrointestinal, cardiovascular, and renal side effects.
Flurbiprofen typically starts to work within a few hours after oral intake. However, the exact time may vary depending on the individual and the condition being managed.
The best time to take Flurbiprofen should be decided in consultation with your doctor, who will consider the severity of your symptoms and other personal health factors.
There are no reported cases of weight gain directly associated with Flurbiprofen use. However, if you experience sudden weight gain, consult your doctor.
Flurbiprofen should be used with caution in patients with hypertension as it might lead to increased blood pressure. It is advised to consult your doctor before starting this medicine.
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