Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 / Pyridoxine is primarily used to manage neuropathic pain. It belongs to a class of medications that blend anticonvulsants with vitamins for nerve support.
Additionally, this combination may be prescribed for specific neuropathic conditions such as diabetic neuropathy, post-herpetic neuralgia, trigeminal neuralgia, and sciatica.
Dizziness
Dry mouth
Weight gain
Edema (swelling)
Difficulty concentrating
Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 / Pyridoxine is a combination of nutritional supplements.
Pregabalin, as an anticonvulsant, disrupts the transmission of pain signals by lessening the release of neurotransmitters that send out pain signals. This results in significant pain relief.
Methylcobalamin, an active form of Vitamin B12, aids in the repair of damaged nerves by supporting the regeneration of myelin, a protective sheath that insulates nerves. It may also have pain-relieving effects by stimulating certain pathways that inhibit pain.
Folic Acid plays a significant role in maintaining the health of the nervous system. It aids in the production of serotonin, dopamine, and norepinephrine, neurotransmitters that modulate pain. Thus, Folic Acid might help improve nerve conduction and reduce neuropathic pain.
Pyridoxine, commonly known as Vitamin B6, is involved in many metabolic processes. It plays a crucial role in the synthesis of neurotransmitters like serotonin and GABA and offers neuroprotective effects.
Doctor of Medicine
BMS, FMC, MD Resident
Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 / Pyridoxine is available in the form of oral capsules and tablets.
This combination is typically prescribed for adults and children over the age of 12 years.
This medicine is contraindicated in people with hypersensitivity to any of the ingredients.
It is also contraindicated in individuals with end-stage renal disease undergoing haemodialysis.
This medicine may interact with CNS depressants like benzodiazepines (such as diazepam), opioids (such as morphine) and anticonvulsants (such as phenytoin, phenobarbital and primidone).
An overdose of this medication can lead to symptoms such as increased drowsiness, blurred vision, unsteady movement or decreased coordination. If these symptoms occur, consult your doctor immediately.
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Most side effects will disappear once you stop taking the medicine. However, if any side effect persists or worsens, consult your doctor immediately.
For dizziness or drowsiness, try resting and avoid driving or operating machinery until these effects have worn off.
If dry mouth occurs, suck on sugarless gum or hard candy.
This medication may cause dizziness and drowsiness which can affect your ability to drive or operate heavy machinery. It is advised to avoid such activities if you feel these effects after taking the medication.
There is insufficient data on the safety of this medicine during pregnancy and breastfeeding. It is advised to consult your doctor before using this medicine during these periods.
Individuals with kidney disease should exercise caution when taking this medication, as the medicine is excreted by the kidneys and may accumulate leading to toxicity.
People with a history of depression or mood disorders should also be monitored closely as this medication can cause suicidal thoughts and behaviours.
Maintain a healthy diet rich in vitamins, especially B vitamins, to support nerve health.
Regular exercise can help manage neuropathic pain.
Good sleep hygiene can help manage sleep disturbances associated with neuropathic pain.
Frequently asked questions
Weight gain may occur as a side effect of Pregabalin, one of the components in this combination. If you experience significant weight changes while taking this medicine, it is advisable to consult your doctor.
Pregabalin, an ingredient in this combination, can occasionally cause mood swings or depressive symptoms in some individuals. If you experience these or any other unusual emotional changes while taking this medicine, please consult your doctor immediately.
No. This medicine should not be taken if you have known hypersensitivity or allergic reactions to any of its ingredients.
The duration of therapy varies according to your specific condition and response to treatment. It is crucial to follow your doctor's instructions regarding the duration of treatment.
Generally, this combination requires a prescription from a doctor, as it is used to manage specific medical conditions. It is not usually available over the counter.
No, Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 / Pyridoxine is not a steroid. It is a combination of vitamins and an anticonvulsant medicine which is used primarily to manage neuropathic pain.
The absorption of pregabalin is not affected by food, so it can be taken with or without food. However, the B-vitamin components are best absorbed with food. To avoid stomach upset, it is preferable to take this medication with food.
Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 / Pyridoxine in other salts
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