Fradiomycin Sulphate is used for managing various bacterial infections and belongs to the class of aminoglycoside antibiotics. It is primarily used to manage intestinal infections (such as intestinal amebiasis), bacterial skin infections when applied as a topical ointment or cream, surgical prophylaxis, and hepatic encephalopathy or hepatic coma.
Nausea
Vomiting
Diarrhoea
Mouth sores or swelling of the tongue
Hearing loss or ringing in the ears
Fradiomycin Sulphate is an aminoglycoside antibiotic.
It works by entering the bacterial cells and attaching irreversibly to a structure called the 30S ribosomal subunit. This attachment disrupts protein synthesis, causing errors and premature termination in the decoding of the bacterial genetic material. This process results in faulty proteins being produced, which cannot perform their normal functions and lead to bacterial cell death.
Additionally, it modifies the bacterial cell membrane permeability, leading to leakage of vital intracellular components. Consequently, this weakens the bacteria and leads to their death.
These combined actions impede bacterial growth and ultimately lead to bacterial cell death, effectively managing the bacterial infection.
BDS, MDS
BMS, FMC, MD Resident
Fradiomycin Sulphate is available for oral use in the form of tablets, capsules, and liquid suspensions.
For topical application, Fradiomycin Sulphate is available in creams and ointments.
It is also used in eye drops or ointments for treating bacterial eye infections.
Dilute solutions of Fradiomycin Sulphate are used for wound irrigation or bladder irrigation to prevent infection.
Fradiomycin Sulphate is suitable for use in adults and children. Specific age restrictions may vary depending on the formulation and medical condition being addressed.
It is contraindicated in individuals with a known allergy to Fradiomycin or other aminoglycosides.
It is also contraindicated in individuals with myasthenia gravis, due to the potential worsening of muscle weakness.
Individuals with intestinal obstruction should also avoid this medicine, as it is poorly absorbed orally under these conditions.
This medicine may interact with diuretics (such as Furosemide and Ethacrynic acid), neuromuscular blocking agents (like Vecuronium and Rocuronium), medications that affect kidney function (such as Cisplatin), and other ototoxic medications (including Aspirin, Ibuprofen).
Overdosing can lead to serious side effects like kidney damage, nerve damage, or hearing loss. If you suspect an overdose, urgent medical intervention is crucial.
If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage nausea or vomiting, consider taking the medication with food or at bedtime.
Increase fluid intake to help manage dry mouth or mild diarrhoea.
It may cause dizziness or drowsiness in some individuals. It is advisable to avoid driving or operating heavy machinery if you experience these side effects.
Fradiomycin Sulphate is generally advised against during pregnancy and breastfeeding unless deemed necessary by a doctor. Consulting a doctor before using this medication during these periods is crucial.
Individuals with pre-existing kidney disease should use this medicine with caution as it can potentially lead to kidney damage.
Those with hearing impairments should also be cautious as this medication can exacerbate hearing loss.
Increase intake of fluids to stay hydrated, especially if experiencing diarrhoea.
Consider a low-residue diet during active intestinal infection to reduce bowel movements and discomfort.
Maintain good personal hygiene, especially handwashing, to prevent the spread of bacteria.
Maintaining adequate hydration is crucial while on this medicine to help manage potential nephrotoxicity and ensure proper renal function.
Frequently asked questions
No, it is not a steroid. It is an antibiotic belonging to the aminoglycoside class known for its potency against various bacterial infections.
No evidence or scientific data suggests that it has any direct effect on sleep. However, side effects like nausea or vomiting might indirectly affect sleep.
While aminoglycoside antibiotics can potentially cause kidney damage in high doses, there is no specific data linking Fradiomycin Sulphate directly to fertility issues. However, it is recommended to discuss your concerns with a doctor.
There are no specific dietary restrictions while you are taking this medicine unless your doctor advises otherwise.
The safety of taking this medicine daily depends on the specific medical condition being managed and the overall health status of the patient. Always follow the dosage guidelines provided by your doctor.
Improvement in symptoms is generally seen within 48-72 hours. However, it is crucial to complete the full course of antibiotic treatment as prescribed by your doctor.
The best time will depend on the specific health conditions being managed and your doctor's recommendations.
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