Gliclazide + Metformin + Pioglitazone

Dosage Forms Available

• Gliclazide + Metformin + Pioglitazone is available for use via the oral route in the form of tablets.

Age and Dose Restrictions

• This combination medicine is intended for use in adults only. It is not meant for children or adolescents under 18 years of age.

Contraindications

• Gliclazide + Metformin + Pioglitazone is contraindicated in patients with hypersensitivity to any of the individual components.

• It should not be used by patients with type 1 diabetes, severe renal or hepatic impairment, or congestive heart failure requiring pharmacologic treatment.

Other Medications to Avoid

• This combination may interact with medicines that induce hyperglycemia (such as corticosteroids and thyroid hormones) and cationic medicines (such as amiloride and digoxin).

Overdose and Missed Dose

• Overdose of Gliclazide + Metformin + Pioglitazone may result in hypoglycemia and lactic acidosis. In such cases, immediate medical attention should be sought.

• If a dose is missed, it should be taken as soon as remembered. However, if it is close to the time for the next dose, the missed dose should be skipped and the regular schedule resumed. Double dosing should be avoided.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help reduce the risk of dehydration and help manage side effects like dry mouth and thirst.

• Taking the medicine with meals can help manage gastrointestinal side effects like nausea and diarrhoea.

Use in Driving and Operating Machinery

• Gliclazide + Metformin + Pioglitazone may cause dizziness or blurred vision. Therefore, caution is advised when driving or operating machinery until you know how the medicine affects you.

Use in Pregnancy and Lactation

• The use of Gliclazide + Metformin + Pioglitazone during pregnancy or while breastfeeding should only be if the potential benefit justifies the potential risk to the foetus or infant. Consult your doctor before using this medicine in pregnancy and breastfeeding.

Caution in Other Conditions

• Patients with moderate renal or hepatic impairment, heart disease, or bladder cancer should exercise caution when taking this medicine.

Special Dietary and Lifestyle Recommendations

• Regular physical activity can help manage blood sugar levels and enhance the effectiveness of this medication.

• A balanced diet low in refined sugars and rich in whole grains, fruits, vegetables, lean proteins, and healthy fats can also support diabetes management.