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Gliclazide + Metformin + Pioglitazone

Uses of Gliclazide + Metformin + Pioglitazone

  • Gliclazide + Metformin + Pioglitazone is primarily used to manage type 2 diabetes mellitus. It belongs to the class of antidiabetic medicines.

  • Besides, it is also used as an adjunctive therapy to diet and exercise in patients who are already treated with a combination of gliclazide and metformin, or whose diabetes is not adequately controlled with metformin alone.

Side effects of Gliclazide + Metformin + Pioglitazone

  • Upper respiratory tract infection

  • Headache

  • Diarrhoea

  • Nausea

How Gliclazide + Metformin + Pioglitazone works

  • Gliclazide + Metformin + Pioglitazone falls under the category of anti-diabetic medicines.

  • Gliclazide is a sulfonylurea class of medicine. It works by stimulating the pancreas to produce more insulin, a hormone that helps control blood sugar levels.

  • Metformin is a biguanide type of medicine. It works by reducing the amount of glucose produced by the liver, slowing down glucose absorption in the intestines, and increasing the body's response to insulin, thus boosting its efficiency in controlling blood sugar levels.

  • Pioglitazone is a thiazolidinedione class of medicine. It improves the body's ability to use insulin by increasing the sensitivity of muscle, fat, and liver cells to insulin.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Gliclazide + Metformin + Pioglitazone is available for use via the oral route in the form of tablets.

Age and Dose Restrictions

  • This combination medicine is intended for use in adults only. It is not meant for children or adolescents under 18 years of age.

Contraindications

  • Gliclazide + Metformin + Pioglitazone is contraindicated in patients with hypersensitivity to any of the individual components.

  • It should not be used by patients with type 1 diabetes, severe renal or hepatic impairment, or congestive heart failure requiring pharmacologic treatment.

Other Medications to Avoid

  • This combination may interact with medicines that induce hyperglycemia (such as corticosteroids and thyroid hormones) and cationic medicines (such as amiloride and digoxin).

Overdose and Missed Dose

  • Overdose of Gliclazide + Metformin + Pioglitazone may result in hypoglycemia and lactic acidosis. In such cases, immediate medical attention should be sought.

  • If a dose is missed, it should be taken as soon as remembered. However, if it is close to the time for the next dose, the missed dose should be skipped and the regular schedule resumed. Double dosing should be avoided.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help reduce the risk of dehydration and help manage side effects like dry mouth and thirst.

  • Taking the medicine with meals can help manage gastrointestinal side effects like nausea and diarrhoea.

Use in Driving and Operating Machinery

  • Gliclazide + Metformin + Pioglitazone may cause dizziness or blurred vision. Therefore, caution is advised when driving or operating machinery until you know how the medicine affects you.

Use in Pregnancy and Lactation

  • The use of Gliclazide + Metformin + Pioglitazone during pregnancy or while breastfeeding should only be if the potential benefit justifies the potential risk to the foetus or infant. Consult your doctor before using this medicine in pregnancy and breastfeeding.

Caution in Other Conditions

  • Patients with moderate renal or hepatic impairment, heart disease, or bladder cancer should exercise caution when taking this medicine.

Special Dietary and Lifestyle Recommendations

  • Regular physical activity can help manage blood sugar levels and enhance the effectiveness of this medication.

  • A balanced diet low in refined sugars and rich in whole grains, fruits, vegetables, lean proteins, and healthy fats can also support diabetes management.

Frequently asked questions

Yes, one of the potential side effects of this medicine is weight gain. If you experience significant weight changes while on this medication, it is recommended to consult your doctor.

The onset of action for this medication varies for each individual and depends on several factors including the severity of the condition and individual response to the medicine. Consult your doctor for more specific information.

No, Gliclazide + Metformin + Pioglitazone is not a steroid. This combination is made up of three different antidiabetic medicines: Gliclazide, which belongs to the sulfonylurea class; Metformin, which is a biguanide; and Pioglitazone, which belongs to the thiazolidinedione class.

Gliclazide + Metformin + Pioglitazone is not commonly associated with sleep disturbances, but some individuals may experience insomnia or altered sleep patterns as side effects.

Gliclazide + Metformin + Pioglitazone is not typically known to affect fertility directly, though Metformin can sometimes improve fertility in women with polycystic ovary syndrome (PCOS).

Yes, it is usually safe to take Gliclazide + Metformin + Pioglitazone daily as prescribed by your doctor. The medicine is designed for long-term use in the management of type 2 diabetes.

This combination medication is usually taken daily as per your doctor's instructions. The exact timing can depend on your schedule and meal times. It is best to take the medication at the same time each day for the most consistent effect.

Terms & Conditions


Available medicines for GLICLAZIDE + METFORMIN + PIOGLITAZONE
Glizid Total P 15 Tablet 10
Glizid Total P 15 Tablet 10
Mankind Pharmaceuticals Ltd.
Pack of 10 Units
â‚ą97.60
MRP â‚ą119.02
18.00% OFF
Aim7 60 Xr Tablet 15
Aim7 60 Xr Tablet 15
Eris Lifesciences Ltd
Pack of 15 Units
â‚ą183.56
MRP â‚ą223.85
18.00% OFF
Glycinorm Total 30 Tablet 15
Glycinorm Total 30 Tablet 15
Ipca Laboratories Pvt Ltd.
Pack of 15 Units
â‚ą141.16
MRP â‚ą172.15
18.00% OFF
Dianorm Total 60 Tablet 10
Dianorm Total 60 Tablet 10
Micro Labs Ltd
Pack of 10 Units
â‚ą115.62
MRP â‚ą141.00
18.00% OFF
Reclimet Pg 60 Tablet 10
Reclimet Pg 60 Tablet 10
Dr. Reddys Laboratories Ltd
Pack of 10 Units
â‚ą111.11
MRP â‚ą135.50
18.00% OFF
New Triclazone 80 Tablet 10
New Triclazone 80 Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
â‚ą129.56
MRP â‚ą158.00
18.00% OFF
Dianorm Total 30 Tablet 10
Dianorm Total 30 Tablet 10
Micro Labs Ltd
Pack of 10 Units
â‚ą76.26
MRP â‚ą93.00
18.00% OFF
Glycinorm Total 60 Tablet 15
Glycinorm Total 60 Tablet 15
Ipca Laboratories Pvt Ltd.
Pack of 15 Units
â‚ą193.19
MRP â‚ą235.60
18.00% OFF

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