Glipizide

Dosage Forms Available

• Glipizide can be taken orally (regular and extended-release tablets).

Age and Dose Restrictions

• Glipizide is intended for use in adults.

Contraindications

• Glipizide is contraindicated in patients with known hypersensitivity to Glipizide or other sulfonylureas. It is also not indicated for patients with type 1 diabetes, diabetic ketoacidosis or severe kidney or liver disease.

Other Medications to Avoid

• Glipizide may interact with antidiabetic medicines (such as insulin, and metformin), beta-blockers (such as propranolol, and metoprolol), corticosteroids (like prednisone), diuretics (like hydrochlorothiazide), anticoagulants (like warfarin) and antifungals (such as fluconazole, and miconazole).

Overdose and Missed Dose

• An overdose of Glipizide may cause symptoms like nausea, vomiting, stomach pain, drowsiness, seizures or unconsciousness. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of Glipizide, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double up the dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage some common side effects like dizziness and headache.

• Taking the medicine with meals helps reduce the risk of stomach upset.

Use in Driving and Operating Machinery

• Glipizide may cause dizziness and blurred vision. Therefore, caution is advised while driving or operating machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

• Glipizide should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Because it is not known whether Glipizide is excreted in human milk, caution should be exercised when Glipizide is administered to a nursing woman.

Caution in Other Conditions

• Patients with G6PD deficiency should use Glipizide with caution as it may cause hemolytic anaemia.

• Patients with kidney or liver impairment may require dose adjustments due to the slower clearance of Glipizide from the body.

Special Dietary and Lifestyle Recommendations

• Avoid high-sugar foods and beverages to prevent blood sugar spikes.

• Regular monitoring of blood glucose levels is recommended for optimal diabetes management.