Glycine
Uses of Glycine
Glycine is primarily used for various health purposes including the management of symptoms in some schizophrenia patients who do not respond to conventional medicines. It belongs to the group of amino acids.
Aside from its main use, Glycine is also explored for potential benefits in improving sleep quality, managing metabolic disorders related to obesity, diabetes, and heart disease, and enhancing memory and cognitive function. Its potential in stroke recovery, muscle growth, and cancer prevention is also under investigation.
Side effects of Glycine
Stomach upset
Nausea
Vomiting
How Glycine works
Glycine is a non-essential amino acid.
It functions as a fundamental building block for proteins, contributing to the structural support of tissues and organs. As an inhibitory neurotransmitter in the central nervous system, it helps regulate brain activity and might play a role in managing conditions like schizophrenia. Glycine is involved in the synthesis of essential biomolecules such as creatine, heme, glutathione, and bile salts. It may also possess anti-inflammatory and antioxidant properties, potentially underpinning its proposed metabolic and neuroprotective benefits.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Glycine is typically available for oral administration in various forms including tablets, capsules, powder, or liquid solutions.
It can also be used as an injectable solution, which is usually administered intravenously.
Age and Dose Restrictions
Glycine may be used by both adults and children over the age of 12 years.
Contraindications
Glycine is contraindicated in individuals with known allergies to the substance itself.
Patients with severe liver or kidney disease should take Glycine with caution.
Other Medications to Avoid
Glycine may interact with antipsychotics (such as clozapine), antidepressants (like fluoxetine), and antiepileptics (such as valproic acid). These interactions could potentially alter the efficacy of these medications or increase the risk of side effects, such as sedation, dizziness, or gastrointestinal discomfort. Additionally, it may interact with muscle relaxants (like baclofen), potentially enhancing their sedative effects.
Overdose and Missed Dose
Overdose of Glycine can lead to symptoms such as nausea, vomiting, stomach upset, and in severe cases, neurological issues. If you suspect an overdose, inform your doctor at once.
In case a dose of Glycine is missed, it should be taken as soon as possible. However, if it is close to the time for the next dose, the missed dose should be skipped.
Management of Side Effects
Most side effects from taking Glycine are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water may help reduce some gastrointestinal side effects such as nausea or upset stomach.
Use in Driving and Operating Machinery
If you feel dizzy or drowsy after taking it, avoid driving or operating machinery.
Use in Pregnancy and Lactation
Always consult your doctor before using this medicine while pregnant or breastfeeding.
Caution in Other Conditions
Patients with kidney or liver disease should take Glycine with caution as they may require dose adjustments.
Special Dietary and Lifestyle Recommendations
Maintain a balanced diet with adequate protein intake, as Glycine is found in substantial amounts in protein-rich foods like meat, fish, dairy, and legumes.
A regular sleep schedule may enhance the potential benefits of Glycine on sleep quality.
Frequently asked questions
Can Glycine aid in improving sleep quality?
Yes, some studies suggest that Glycine may help improve sleep quality and reduce daytime sleepiness and fatigue. However, more research is needed to confirm this.
Is Glycine a type of protein?
No, Glycine is not a type of protein. It is an amino acid which acts as a building block for proteins.
Will Glycine affect fertility?
Glycine is not associated with affecting fertility in any way. It is always safer to consult your doctor for guidance on this topic.
Is it safe to take Glycine daily?
The safety of taking Glycine daily would depend on the individual's health condition and the dose recommended by the doctor.
Does Glycine work immediately or does it take time?
The time taken for Glycine to show its effects can vary depending on the individual and the specific health condition it is being used to manage.
What is the best time to take Glycine?
The best time to take Glycine would depend on the specific instructions given by your doctor.
Is Glycine beneficial for brain function?
Glycine plays a role in transmitting chemical signals in the brain which may enhance memory and cognitive function. However, these potential benefits are still under investigation and more evidence is required to confirm them.
Glycine in other salts
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