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Haloperidol + Trihexyphenidyl

Uses of Haloperidol + Trihexyphenidyl

  • Haloperidol + Trihexyphenidyl is primarily used to manage schizophrenia and belongs to the group of antipsychotic and anticholinergic medicines.

  • There are secondary uses for this combination as well, such as managing severe behavioural disorders in children when other treatments have been ineffective.

Side effects of Haloperidol + Trihexyphenidyl

  • Dry mouth

  • Constipation

  • Blurred vision

  • Drowsiness

  • Difficulty urinating

How Haloperidol + Trihexyphenidyl works

  • Haloperidol + Trihexyphenidyl is a combination of an antipsychotic and an anticholinergic agent.

  • Haloperidol, the antipsychotic component, works by blocking dopamine receptors in the brain, especially the D2 receptors. Dopamine is a neurotransmitter that plays a key role in controlling our mood, thinking patterns, and behaviours. By impeding the activity of dopamine, haloperidol helps manage symptoms of psychosis such as hallucinations and delusions, but can also lead to extrapyramidal side effects.

  • Trihexyphenidyl, the anticholinergic component, obstructs the action of acetylcholine, another neurotransmitter. This counteracts the extrapyramidal side effects caused by haloperidol, including muscle spasms and restlessness.

  • The combined action of both of these ingredients aids in managing schizophrenia and reducing the side effects associated with antipsychotic medicine use.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Haloperidol + Trihexyphenidyl is available in the form of tablets and oral solutions, which are to be taken orally.

Age and Dose Restrictions

  • This medication is typically recommended for adults and children over the age of 12 years.

Contraindications

  • Haloperidol + Trihexyphenidyl should not be given to patients suffering from severe central nervous system depression.

  • It is also contraindicated in patients with a history of QT prolongation or other heart rhythm disorders and in those diagnosed with Parkinson's disease.

Other Medications to Avoid

  • This combination may interact with other anticholinergics (such as benztropine and oxybutynin), antidepressants (such as fluoxetine and paroxetine), antihistamines (such as diphenhydramine and levocetirizine), antihypertensives (such as propranolol and atenolol), and Parkinson's disease medications (such as levodopa and carbidopa).

Overdose and Missed Dose

  • Overdose symptoms can include severe drowsiness, confusion, agitation, irregular heartbeat, and muscle stiffness. Seek emergency medical attention immediately if you suspect an overdose.

  • If a dose is missed, take the medicine as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water can help manage side effects like dry mouth and constipation.

  • Rest and avoiding sudden movements can help manage dizziness.

  • Make sure to take this medicine with food to help reduce any potential stomach upset.

Use in Driving and Operating Machinery

  • Haloperidol + Trihexyphenidyl may cause drowsiness and dizziness. If affected, you should not drive or operate machinery until these symptoms subside.

Use in Pregnancy and Lactation

  • The safety of Haloperidol + Trihexyphenidyl during pregnancy has not been established. It is advised to consult a doctor before using this combination during pregnancy or breastfeeding.

Caution in Other Conditions

  • Patients with a history of seizures, heart problems, liver or kidney disease, glaucoma, or urinary retention should use Haloperidol + Trihexyphenidyl with caution.

Special Dietary and Lifestyle Recommendations

  • Practising good sleep hygiene can also help manage any potential sleep disturbances caused by this medication.

  • Regular, light physical activity like walking or stretching can be beneficial in managing restlessness that could potentially be caused by this medicine.

Frequently asked questions

No, Haloperidol + Trihexyphenidyl is not a steroid. It is a combination of an antipsychotic agent and an anticholinergic agent used to manage schizophrenia and extrapyramidal symptoms.

Haloperidol + Trihexyphenidyl may cause drowsiness as one of its side effects, which can impact your sleep. If you feel excessively sleepy after taking this medication, consult your doctor.

There is no clear evidence that Haloperidol + Trihexyphenidyl directly affects fertility in humans. However, if you have concerns about fertility, it is best to discuss them with your doctor.

There are no specific diet restrictions for taking Haloperidol + Trihexyphenidyl unless your doctor advises otherwise. However, maintaining a balanced diet while on medication can contribute to overall well-being.

Haloperidol + Trihexyphenidyl should be taken exactly as prescribed by your doctor. The frequency and duration of the medicine are determined based on your condition and response to treatment.

The onset of action varies, but some effects may be seen within a few days of starting the treatment. Full benefits may take several weeks to appear.

The best time to take Haloperidol + Trihexyphenidyl is as advised by your doctor. It is generally recommended to take it at the same time every day for maximum efficacy.

Terms & Conditions


Available medicines for HALOPERIDOL + TRIHEXYPHENIDYL
Trinorm 10/2 MG Tablet 8
Trinorm 10/2 MG Tablet 8
Sun Pharma Laboratories Ltd.
Pack of 8 Units
₹21.80
MRP ₹26.58
18.00% OFF
Cizoren Plus 5/2 MG Tablet 10
Cizoren Plus 5/2 MG Tablet 10
Stadmed Pvt. Ltd
Pack of 10 Units
₹14.92
MRP ₹18.20
18.00% OFF
Talendol-t 10/2 MG Tablet 10
Talendol-t 10/2 MG Tablet 10
Talent India
Pack of 10 Units
₹12.30
MRP ₹15.00
18.00% OFF
Trinorm 1.5/2 MG Tablet 10
Trinorm 1.5/2 MG Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹200.90
MRP ₹245.00
18.00% OFF
Trinorm 5/2 MG Tablet 10
Trinorm 5/2 MG Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹200.90
MRP ₹245.00
18.00% OFF
Erifol H 5/2 MG Tablet 10
Erifol H 5/2 MG Tablet 10
Eridanus Healthcare
Pack of 10 Units
₹32.80
MRP ₹40.00
18.00% OFF
Trinorm 1.5/2 MG Tablet 8
Trinorm 1.5/2 MG Tablet 8
Sun Pharma Laboratories Ltd.
Pack of 8 Units
₹6.56
MRP ₹8.00
18.00% OFF
Trinorm 10/2 MG Tablet 10
Trinorm 10/2 MG Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹200.90
MRP ₹245.00
18.00% OFF

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