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Hydrochlorothiazide + Irbesartan

Uses of Hydrochlorothiazide + Irbesartan

  • The primary use of Hydrochlorothiazide + Irbesartan is to manage high blood pressure (hypertension). This medicine belongs to the group of angiotensin II receptor blockers (ARBs) and thiazide diuretics.

  • In certain instances, Hydrochlorothiazide + Irbesartan may be used to reduce the risk of death following a heart attack.

Side effects of Hydrochlorothiazide + Irbesartan

  • Dizziness

  • Fatigue

  • Headache

  • Nausea

  • Muscle pain

How Hydrochlorothiazide + Irbesartan works

  • Hydrochlorothiazide + Irbesartan is a combination medicine used to manage high blood pressure.

  • Hydrochlorothiazide, classified as a thiazide diuretic, functions by increasing urine output. This process helps the body eliminate excessive salt and water, resulting in lower blood volume and consequently decreased blood pressure.

  • Irbesartan is an angiotensin II receptor blocker, which acts by relaxing and widening blood vessels. It does so by inhibiting the action of angiotensin II, a hormone that usually narrows blood vessels. This action improves blood flow and reduces blood pressure.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Hydrochlorothiazide + Irbesartan is accessible for oral administration in the form of tablets.

Age and Dose Restrictions

  • This medication is intended for use in adults only.

Contraindications

  • Hydrochlorothiazide + Irbesartan is contraindicated in patients with known hypersensitivity to sulfa-derived medicines.

  • It is also contraindicated in individuals with severe renal impairment or anuria (non-production of urine).

Other Medications to Avoid

  • This combination may interact with other blood pressure medications (such as beta-blockers like atenolol and metoprolol), diuretics (including furosemide and spironolactone), NSAIDs (such as ibuprofen and naproxen), lithium, potassium supplements, and insulin or oral diabetes medications (like metformin and glibenclamide).

Overdose and Missed Dose

  • An overdose of Hydrochlorothiazide + Irbesartan may lead to symptoms such as extreme dizziness, dehydration, electrolyte imbalance, or low blood pressure. Immediate medical attention is required in cases of suspected overdose.

  • If you miss a dose of Hydrochlorothiazide + Irbesartan, take it as soon as you remember unless it is almost time for your next dose. In that scenario, skip the missed dose; do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Dizziness can be managed by rising slowly from sitting or lying positions.

  • For dehydration risk due to increased urination, maintain adequate fluid intake.

Use in Driving and Operating Machinery

  • Hydrochlorothiazide + Irbesartan can cause dizziness. It is advisable to avoid driving or operating heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

  • Hydrochlorothiazide + Irbesartan is not recommended during pregnancy or while breastfeeding due to potential risks to the baby. Women who are pregnant or planning to become pregnant should consult their doctor before using this medication.

Caution in Other Conditions

  • Caution is advised when using Hydrochlorothiazide + Irbesartan in patients with kidney disease or liver disease as it may require dose adjustments or specific monitoring.

  • Individuals with congestive heart failure should also use this medicine cautiously.

Special Dietary and Lifestyle Recommendations

  • For effective management of hypertension, adopt a diet low in salt and sodium. Prefer fresh fruits, vegetables, whole grains, and lean proteins over processed foods high in sodium.

  • Engage in regular physical activity such as brisk walking or cycling for at least 150 minutes per week to help lower and control blood pressure.

  • Monitor your blood pressure regularly to assess the effectiveness of the medication combined with lifestyle changes.

  • Limit alcohol consumption as it can raise blood pressure and reduce the effectiveness of this medication.

  • Manage stress through relaxation techniques such as deep breathing, meditation, or yoga which can positively affect blood pressure levels.

  • Maintain a healthy body weight; even a small amount of weight loss can significantly lower high blood pressure.

Frequently asked questions

No, Hydrochlorothiazide + Irbesartan does not usually cause weight gain. However, if you notice unusual weight gain, consult your doctor.

Hydrochlorothiazide + Irbesartan is generally safe for long-term use if taken under the supervision of your doctor.

If you have diabetes, you should consult your doctor before taking Hydrochlorothiazide + Irbesartan as it may affect your blood sugar levels.

While some patients report hair loss, this side effect is not commonly associated with Hydrochlorothiazide + Irbesartan. If you notice hair loss, consult your doctor.

There are no reports of Hydrochlorothiazide + Irbesartan affecting mood or mental health. However, if you experience mood changes or mental health issues while on this medication, consult your doctor.

Hydrochlorothiazide + Irbesartan can be taken with or without food. However, it is usually recommended to take it at the same time each day.

There is no common evidence to suggest that Hydrochlorothiazide + Irbesartan impacts the menstrual cycle. If you notice changes in your cycle, consult your doctor.

Terms & Conditions


Available medicines for HYDROCHLOROTHIAZIDE + IRBESARTAN
Coaprovel 300/12.5 MG Tablet 14
Coaprovel 300/12.5 MG Tablet 14
Sanofi India Ltd.
Pack of 14 Units
₹262.89
MRP ₹320.60
18.00% OFF
Irbetag H Tablet 10
Irbetag H Tablet 10
Ikon Remedies Pvt Ltd
Pack of 10 Units
₹97.30
MRP ₹195.00
50.10% OFF
Xarb H 150/12.5 MG Tablet 10
Xarb H 150/12.5 MG Tablet 10
Abbott Healthcare Pvt. Ltd
Pack of 10 Units
₹184.66
MRP ₹225.20
18.00% OFF
Insat H Tablet 10
Insat H Tablet 10
East West Pharma
Pack of 10 Units
₹86.92
MRP ₹106.00
18.00% OFF
Irovel H Tablet 10
Irovel H Tablet 10
Sun Pharma Laboratories Ltd.
Pack of 10 Units
₹139.40
MRP ₹170.00
18.00% OFF
Coaprovel 150/12.5 MG Tablet 14
Coaprovel 150/12.5 MG Tablet 14
Sanofi India Ltd.
Pack of 14 Units
₹213.20
MRP ₹260.00
18.00% OFF

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