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Hydrochlorothiazide + Quinapril

Uses of Hydrochlorothiazide + Quinapril

  • The chief use of Hydrochlorothiazide + Quinapril is to manage high blood pressure (hypertension). It belongs to the group of antihypertensive medicines.

  • Occasionally, doctors may prescribe this medicine to address fluid retention (edema) associated with conditions such as heart failure, liver cirrhosis, or kidney disorders. In these cases, it assists in reducing excess fluid build-up in the body.

Side effects of Hydrochlorothiazide + Quinapril

  • Dizziness or lightheadedness

  • Fatigue or weakness

  • Dry cough

  • Nausea or vomiting

  • Increased urination

How Hydrochlorothiazide + Quinapril works

  • Hydrochlorothiazide + Quinapril is a combination used to manage hypertension.

  • Hydrochlorothiazide is a thiazide diuretic. It increases urine production by encouraging the kidneys to remove more sodium and water from the body. This reduces the fluid volume in the blood vessels, thereby lowering blood pressure.

  • Quinapril is an angiotensin-converting enzyme (ACE) inhibitor. It relaxes blood vessels and decreases blood volume by blocking the action of an enzyme that produces a substance that narrows blood vessels. This makes it easier for the heart to pump blood.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Hydrochlorothiazide + Quinapril is available for use as tablets, which are taken orally.

Age and Dose Restrictions

  • This medicine is meant for adults only.

Contraindications

  • This medicine is contraindicated in patients with known allergies to quinapril, hydrochlorothiazide, or other ACE inhibitors or sulfa medicines.

  • This medicine is contraindicated in patients with severe kidney or liver disease and in those with anuria (complete absence of urine production).

Other Medications to Avoid

  • This combination may interact with potassium supplements or potassium-sparing diuretics (such as spironolactone and triamterene), lithium, nonsteroidal anti-inflammatory drugs (NSAIDs like ibuprofen and naproxen), insulin, or oral diabetes medications (such as metformin and glyburide).

Overdose and Missed Dose

  • Symptoms of overdose may include severe dizziness, fainting, or a rapid heartbeat. If an overdose is suspected, seek emergency medical attention promptly.

  • If you miss a dose of Hydrochlorothiazide + Quinapril, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing dizziness or lightheadedness, try sitting or lying down until the feeling passes.

  • Stay well hydrated to help manage minor side effects such as dry mouth or thirst.

Use in Driving and Operating Machinery

  • This medication may impair your ability to drive or operate machinery. Avoid such activities until you know how Hydrochlorothiazide + Quinapril affects you, especially if you feel dizzy or sleepy.

Use in Pregnancy and Lactation

  • Hydrochlorothiazide + Quinapril is not recommended during pregnancy or while breastfeeding. It could potentially cause harm to the baby. It is crucial to consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before using this medication.

Caution in Other Conditions

  • Patients with renal (kidney) conditions should approach the use of Hydrochlorothiazide + Quinapril with caution due to potential worsening of kidney function.

  • Patients with liver conditions should also be cautious, as dose adjustments might be needed due to slow medicine metabolism.

  • Regular monitoring of electrolytes is important due to potential imbalances caused by the diuretic effect.

Special Dietary and Lifestyle Recommendations

  • Maintain a diet low in sodium. Aim for less than 2 grams of sodium per day.

  • Include potassium-rich foods like bananas, oranges, and spinach, but do so under guidance from your doctor since potassium levels need careful management when taking this medication.

  • Engage in regular physical activity such as walking, jogging, or swimming for at least 30 minutes most days of the week.

  • Limit intake of alcohol as it can increase blood pressure and may reduce the effectiveness of this medicine.

Frequently asked questions

No, Hydrochlorothiazide + Quinapril is not a steroid. It is a combination medication that includes a diuretic (hydrochlorothiazide) and an angiotensin-converting enzyme (ACE) inhibitor (quinapril).

The side effects of Hydrochlorothiazide + Quinapril can vary from person to person. Some people might experience dizziness or lightheadedness, which could potentially affect sleep. However, this is not a commonly reported effect.

Hydrochlorothiazide + Quinapril is generally safe for long-term use if taken as directed by your doctor. It is important to monitor your health and consult your doctor regularly while on this medication.

If you have kidney disease, Hydrochlorothiazide + Quinapril should be used with caution. This is because the medication can potentially worsen kidney function. Always consult your doctor before starting any new medication.

Weight gain is not a common side effect of Hydrochlorothiazide + Quinapril. However, if you experience sudden weight gain or swelling in the hands, ankles, or feet, it could be a sign of fluid retention, and you should contact your doctor.

You should only take potassium supplements while on Hydrochlorothiazide + Quinapril under the direction of your doctor, as this combination can lead to dangerously high levels of potassium.

While it's uncommon, Hydrochlorothiazide + Quinapril could potentially cause mood changes in some individuals. If you experience any unusual changes in mood or behavior, contact your doctor immediately.

Terms & Conditions


Available medicines for HYDROCHLOROTHIAZIDE + QUINAPRIL
Acupil H 10/12.5 MG Tablet 10
Acupil H 10/12.5 MG Tablet 10
Pfizer Ltd
Pack of 10 Units
₹61.50
MRP ₹75.00
18.00% OFF
Qpril H 10/12.5 MG Tablet 10
Qpril H 10/12.5 MG Tablet 10
Macleods Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹53.96
MRP ₹65.81
18.00% OFF
Acupil H 20/12.5 MG Tablet 10
Acupil H 20/12.5 MG Tablet 10
Pfizer Ltd
Pack of 10 Units
₹98.70
MRP ₹120.36
18.00% OFF
Q Press H 20/12.5 MG Tablet 10
Q Press H 20/12.5 MG Tablet 10
Aristo Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹70.69
MRP ₹86.21
18.00% OFF

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