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Hydrochlorothiazide + Ramipril

Uses of Hydrochlorothiazide + Ramipril

  • Hydrochlorothiazide + Ramipril is primarily used to manage hypertension, and it falls under the group of antihypertensive medications.

  • Besides managing hypertension, this medicine also helps in reducing the risk of associated cardiovascular events like heart attack and stroke.

Side effects of Hydrochlorothiazide + Ramipril

  • Dizziness

  • Lightheadedness (common feeling of dizziness)

  • Headache

  • Fatigue

  • Nausea, vomiting, diarrhoea

How Hydrochlorothiazide + Ramipril works

  • Hydrochlorothiazide + Ramipril is a potent combination of antihypertensive medicines.

  • Hydrochlorothiazide, classified as a thiazide diuretic, operates by assisting the kidneys in eliminating excess salt and water from your body. This process decreases blood volume, resulting in reduced blood pressure.

  • Ramipril falls under the category of medicines known as angiotensin-converting enzyme (ACE) inhibitors. It hampers the production of a substance called angiotensin II that causes blood vessels to constrict. By reducing levels of this substance, Ramipril enables blood vessels to relax and widen, further helping to lower blood pressure.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Hydrochlorothiazide + Ramipril is available for use via the oral route in the form of tablets.

Age and Dose Restrictions

  • This medicine is primarily meant for adults. It may also be prescribed for adolescents aged 16 years and above under the close supervision of a doctor.

Contraindications

  • Hydrochlorothiazide + Ramipril is contraindicated in patients with known allergies to either Hydrochlorothiazide or Ramipril. It is also contraindicated in patients with a history of angioedema (swelling in the deeper layers of the skin) related to previous ACE inhibitor therapy, as well as in patients with anuria (a condition that occurs when someone produces little to no urine) or renal artery stenosis (narrowing of the one or both of renal arteries).

Other Medications to Avoid

  • This combination may interact with diuretics (e.g, furosemide, spironolactone), nonsteroidal anti-inflammatory medicines (e.g., ibuprofen, naproxen), antihypertensives (e.g., losartan, valsartan) and potassium-supplementing medicines (e.g., spironolactone, triamterene).

Overdose and Missed Dose

  • An overdose of Hydrochlorothiazide + Ramipril may result in severe hypotension (low blood pressure) and kidney failure. If you suspect an overdose, seek immediate medical attention.

  • If you forget to take your dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drink plenty of fluids to counteract dizziness and prevent dehydration.

  • Rise slowly from sitting or lying positions to avoid lightheadedness.

Use in Driving and Operating Machinery

  • Hydrochlorothiazide + Ramipril may cause dizziness or lightheadedness, which could affect your ability to drive or operate heavy machinery. If you experience these side effects, avoid such activities until you feel better.

Use in Pregnancy and Lactation

  • Hydrochlorothiazide + Ramipril is not recommended for use during pregnancy, especially in the 2nd and 3rd trimesters. Breastfeeding women should use this medication with caution and only under a doctor's supervision.

Caution in Other Conditions

  • Patients with kidney disease, liver disease, or diabetes should exercise caution when taking Hydrochlorothiazide + Ramipril. This medication may worsen gout or increase blood glucose levels, so it should be used with caution in patients with these conditions.

Special Dietary and Lifestyle Recommendations

  • Reduce the intake of sodium-rich foods can help manage hypertension.

  • Regular monitoring of blood pressure is necessary to keep track of the condition.

Frequently asked questions

No, Hydrochlorothiazide + Ramipril is not a steroid. It is a combination of two medicines: a thiazide diuretic and an angiotensin-converting enzyme (ACE) inhibitor.

No specific information suggests that Hydrochlorothiazide + Ramipril directly affects fertility in men or women. However, if you are planning a pregnancy or have concerns about fertility, it is advisable to consult your doctor before using this medication.

You should follow your doctor's instructions regarding dosage and frequency of use of Hydrochlorothiazide + Ramipril.

The time it takes for Hydrochlorothiazide + Ramipril to lower blood pressure can vary between individuals. Some people may notice an improvement within a few hours, while for others, it may take several days or even weeks. Consistent use as directed by your doctor is key for this medication to work effectively.

Your doctor will advise you on the best time to take Hydrochlorothiazide + Ramipril based on your specific condition and routine. It is essential to take the medication at the same time each day for it to work effectively.

There is no substantial evidence to suggest that Hydrochlorothiazide + Ramipril directly affects the menstrual cycle. However, if you notice any changes in your menstrual pattern while taking this medication, consult your doctor promptly.

As with most long-term medications used for the management of chronic conditions like hypertension, abrupt discontinuation of Hydrochlorothiazide + Ramipril may lead to a rebound effect, causing your blood pressure to rise. Always consult your doctor before stopping any medication.

Terms & Conditions


Available medicines for HYDROCHLOROTHIAZIDE + RAMIPRIL
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Cardace H 2.5 Tablet 15
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Cardace H 5 Tablet 15
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