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Hydrocortisone + Hydroquinone + Tretinoin

Uses of Hydrocortisone + Hydroquinone + Tretinoin

  • The primary use of Hydrocortisone + Hydroquinone + Tretinoin is to manage moderate to severe melasma of the face in adults. This medication belongs to the group of topical skincare treatments that combine a corticosteroid, a skin-lightening agent, and a retinoid.

Side effects of Hydrocortisone + Hydroquinone + Tretinoin

  • Skin redness

  • Skin peeling

  • Burning sensation

  • Dryness

  • Itching

How Hydrocortisone + Hydroquinone + Tretinoin works

  • Hydrocortisone belongs to the corticosteroids class of medicines. It works by suppressing your body's immune response, thus reducing inflammation, redness, and itching on the skin surface.
  • Hydroquinone is a skin-lightening agent, that works by reducing melanin production, the pigment responsible for darkening the skin.
  • Tretinoin is a retinoid, that promotes the shedding of hyperpigmented skin cells, revealing fresher, lighter skin.
  • Together, these components improve the appearance of melasma (a skin condition characterized by brown patches on the face), making the skin look lighter and brighter.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Hydrocortisone + Hydroquinone + Tretinoin is available as a cream formulation for topical application on the skin.

Age and Dose Restrictions

  • This medicine is meant for adults. It is not recommended for children or adolescents under 18 years of age.

Contraindications

  • This medicine should not be used by individuals with a history of allergic reactions to any of its active ingredients, including hydrocortisone, hydroquinone, or tretinoin.

Other Medications to Avoid

  • This medicine may interact with photosensitizers (e.g., thiazides, tetracyclines, fluoroquinolones, phenothiazines, and sulfonamides).

Overdose and Missed Dose

  • Overdose of this combination is unlikely as it is intended for external use only. Using the prescribed dosage is recommended to avoid any side effects.

  • If you miss an application of this medicine, apply it as soon as you remember. However, if it is close to the time for your next application, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If you experience dryness or a burning sensation at the application site, use a mild moisturizer to soothe the area.

  • Redness or itching in the treated area can be managed by avoiding exposure to hot temperatures and direct sunlight.

  • If skin peeling occurs, do not peel off the loose skin; let it fall off naturally.

Use in Driving and Operating Machinery

  • Hydrocortisone + Hydroquinone + Tretinoin is a topical application and does not generally affect your ability to drive or operate machinery.

Use in Pregnancy and Lactation

  • Hydrocortisone + Hydroquinone + Tretinoin is not recommended for use by pregnant or lactating women due to potential risks associated with Tretinoin. Please consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Individuals with a history of hypersensitive skin reactions or any form of skin cancer should exercise caution when using this medicine.

Special Dietary and Lifestyle Recommendations

  • Regular use of a broad-spectrum sunscreen with an SPF of 30 or higher is recommended while using this medication to prevent further darkening of the skin.

  • Limit sun exposure especially during the peak hours (10 am to 4 pm) when the UV radiation is at its strongest.

  • Wear protective clothing such as hats and long sleeves when going out in the sun.

  • Avoid using harsh skin products (like soaps, shampoos, or cosmetics) that can irritate the skin.

  • Maintain proper hydration to prevent dryness and flaking of the skin.

Frequently asked questions

Hydrocortisone + Hydroquinone + Tretinoin is a combination medication designed to manage melasma, a skin condition characterised by brown or greyish-brown patches, primarily on the face.

The effect of Hydrocortisone + Hydroquinone + Tretinoin may be observed within 4 weeks of consistent usage. For optimal results, it is typically used for 8–12 weeks.

There is no evidence to suggest that this medicine directly affects sleep. However, if you experience unusual symptoms such as insomnia or excessive sleepiness, consult your doctor.

It is recommended to avoid using other potentially irritating skincare products while using this medication. Consult your doctor for guidance on compatible skincare products.

The safety and effectiveness of prolonged use of Hydrocortisone + Hydroquinone + Tretinoin have not been established. It is typically prescribed for short-term use (8–12 weeks).

Melasma may recur after discontinuing the medication. Therefore, it is crucial to consult your doctor before stopping the medication or for any maintenance therapy.

There is no documented data suggesting that this combination affects fertility. Nonetheless, if you are planning for pregnancy, consult your doctor before starting this medicine.

Terms & Conditions


Available medicines for HYDROCORTISONE + HYDROQUINONE + TRETINOIN
Lomela Lite Cream 10gm
Lomela Lite Cream 10gm
Intas Pharmaceuticals Ltd
Pack of 10 GM
₹79.54
MRP ₹97.00
18.00% OFF
Melalite Plus 2/0.05/1 % Cream 15 GM
Melalite Plus 2/0.05/1 % Cream 15 GM
Abbott Healthcare Pvt. Ltd
Pack of 15 GM
₹104.98
MRP ₹128.03
18.00% OFF
Acnon Hq Cream 15 GM
Acnon Hq Cream 15 GM
Gary Pharma Sande
Pack of 15 GM
₹61.50
MRP ₹75.00
18.00% OFF
Melanorm Hc Cream 15gm
Melanorm Hc Cream 15gm
Unimarck Healthcare Ltd
Pack of 15 GM
₹112.34
MRP ₹137.00
18.00% OFF
Melacare Hc Cream 15 GM
Melacare Hc Cream 15 GM
Ajanta Pharma Ltd
Pack of 15 GM
₹78.91
MRP ₹96.23
18.00% OFF
Nolasma Cream 15gm
Nolasma Cream 15gm
Prism Lifescience
Pack of 15 GM
₹141.04
MRP ₹172.00
18.00% OFF
Melanorm Hc Forte Cream 15 GM
Melanorm Hc Forte Cream 15 GM
Unimarck Healthcare Ltd
Pack of 15 GM
₹72.16
MRP ₹88.00
18.00% OFF
A Ret Hc Cream 15gm
A Ret Hc Cream 15gm
Menarini India
Pack of 15 GM
₹147.60
MRP ₹180.00
18.00% OFF

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