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Hydroxyprogesterone Caproate

Uses of Hydroxyprogesterone Caproate

  • Hydroxyprogesterone Caproate is primarily used in pregnant women who have a history of preterm birth to help manage the risk of delivering prematurely again. It belongs to the group of progestin hormones.

Side effects of Hydroxyprogesterone Caproate

  • Injection site reactions

  • Urticaria

  • Pruritus

  • Nausea

  • Diarrhea

How Hydroxyprogesterone Caproate works

  • Hydroxyprogesterone Caproate is a synthetic progestin hormone.

  • It works by supporting the uterine lining and reducing uterine contractions, helping to maintain pregnancy. It is typically administered as an intramuscular injection during the second trimester of pregnancy.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Hydroxyprogesterone Caproate is available as an injection intended for intramuscular administration.

  • The medication is usually administered into the muscle, typically in the upper outer quadrant of the buttocks.

Age and Dose Restrictions

  • This medicine is specifically meant for adult women who are pregnant and have a history of preterm birth.

Contraindications

  • Hydroxyprogesterone Caproate is contraindicated in individuals with a current or past history of thrombosis or thromboembolic disorders. It should not be used in cases of known or suspected hormone-sensitive cancers, such as breast cancer, or individuals with undiagnosed abnormal vaginal bleeding unrelated to pregnancy. Additionally, it is contraindicated in those with cholestatic jaundice of pregnancy, liver tumors or active liver disease, and uncontrolled hypertension.

Other Medications to Avoid

  • Hydroxyprogesterone Caproate may interact with several medications, including corticosteroids (such as prednisone), anticoagulants (like warfarin), and certain anticonvulsants (such as phenytoin or carbamazepine).

Overdose and Missed Dose

  • An overdose of Hydroxyprogesterone Caproate could potentially intensify side effects such as nausea or injection site reactions. It is important to follow all dosing instructions provided by your doctor.

  • If a dose is missed, you should take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose. Do not double doses.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea, try eating smaller, more frequent meals and avoid rich or fatty foods.

  • For injection site reactions such as pain or swelling, applying a cold compress can provide relief.

Use in Driving and Operating Machinery

  • Hydroxyprogesterone Caproate does not typically affect the ability to drive or operate machinery. However, individual reactions can vary.

Use in Pregnancy and Lactation

  • Hydroxyprogesterone Caproate is specifically indicated for use during pregnancy to help prevent preterm births. It is classified under Pregnancy Category B.

  • The medication is minimally excreted in breast milk and has not shown adverse effects on breastfed infants; however, it is advisable to consult your doctor before use during breastfeeding.

Caution in Other Conditions

  • Caution should be used when administering this medicine to women with diabetes, depression, or a history of major mood disorders.

  • Obesity and age over 35 may also require cautious use and close monitoring during treatment with Hydroxyprogesterone Caproate.

Special Dietary and Lifestyle Recommendations

  • Since Hydroxyprogesterone Caproate is used to manage risks associated with preterm birth, maintaining a healthy lifestyle during pregnancy is crucial.

  • Follow a balanced diet rich in fruits, vegetables, whole grains, and lean proteins to support overall health.

  • Adequate hydration is important; aim for at least eight glasses of water per day.

  • Regular prenatal check-ups are vital for monitoring the health of both mother and baby.

Frequently asked questions

Hydroxyprogesterone Caproate is used to manage the risk of preterm birth in women who have had a previous preterm birth.

It is given as an injection by a healthcare provider, typically into the upper outer quadrant of the buttocks.

No, Hydroxyprogesterone Caproate cannot stop preterm labor that has already started. It is used to manage the risk of preterm birth before it begins.

Rare but serious potential adverse effects include thrombotic events (blood clots), allergic reactions, jaundice, and depression. It is important to seek medical attention if you experience symptoms of these conditions while using this medicine.

There is no evidence suggesting it causes harm to the baby. It has been used for many years to help reduce the risk of preterm birth, but always discuss its benefits and risks with your doctor.

If you have a known allergy to progesterone or any ingredients in Hydroxyprogesterone Caproate, you should inform your doctor. They may suggest an alternative treatment.

Yes, weight gain can occur as a side effect due to fluid retention and hormone-related changes in the body. If you experience rapid or significant weight gain, consult your doctor.

Terms & Conditions

Available medicines for HYDROXYPROGESTERONE CAPROATE
Progestone 500 Injection 2ml
Progestone 500 Injection 2ml
Knoll Healthcare Pvt. Ltd.
Pack of 2 ML
₹180.40
MRP ₹220.00
18.00% OFF
Hydroprogress 500 Injection 2ml
Hydroprogress 500 Injection 2ml
Steris Healthcare
Pack of 2 ML
₹122.18
MRP ₹149.00
18.00% OFF
Hydroprogress 250 Injection 2ml
Hydroprogress 250 Injection 2ml
Steris Healthcare
Pack of 2 ML
₹66.01
MRP ₹80.50
18.00% OFF
Xygest 500 Injection 1
Xygest 500 Injection 1
Chemo Health Care Pvt Ltd
Pack of 1 UNITS
₹154.98
MRP ₹189.00
18.00% OFF
Progestone 250 Injection 1ml
Progestone 250 Injection 1ml
Knoll Healthcare Pvt. Ltd.
Pack of 1 ML
₹104.96
MRP ₹128.00
18.00% OFF
Xygest 250 Injection 1
Xygest 250 Injection 1
Chemo Health Care Pvt Ltd
Pack of 1 UNITS
₹122.18
MRP ₹149.00
18.00% OFF

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